LOCUS BC035321 2287 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens gasdermin C, mRNA (cDNA clone MGC:21665
IMAGE:4753282), complete cds.
ACCESSION BC035321
VERSION BC035321.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2287)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2287)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: James Cleaver, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 28 Row: p Column: 22
This clone grew slowly and was rescued by PCR.
FEATURES Location/Qualifiers
source 1..2287
/db_xref="H-InvDB:HIT000093825"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:21665 IMAGE:4753282"
/tissue_type="Skin, squamous cell carcinoma"
/clone_lib="NCI_CGAP_Skn4"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6.1"
gene 1..2287
/gene="GSDMC"
/gene_synonym="MLZE"
/db_xref="GeneID:56169"
/db_xref="HGNC:HGNC:7151"
/db_xref="MIM:608384"
CDS 428..1954
/gene="GSDMC"
/gene_synonym="MLZE"
/codon_start=1
/product="gasdermin C"
/protein_id="AAH35321.1"
/db_xref="GeneID:56169"
/db_xref="HGNC:HGNC:7151"
/db_xref="MIM:608384"
/translation="MPSMLERISKNLVKEIGSKDLTSVKYLLSATKLRQFVILRKKKD
SRSSFWEQSDYVPVEFSLNDILEPSSSVLETVVTGPFHFSDIMIQKHKADMGVNVGIE
VSVSGEASVDHGCSLEFQIVTIPSPNLEDFQKRKLLDPEPSFLKECRRRGDNLYVVTE
AVELINNTVLYDSSSVNILGKIALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRK
QLVIKEKAILISDDDEQRTFQDEYEISEMVGYCAARSEGLLPSFHTISPTLFNASSND
MKLKPELFLTQQFLSGHLPKYEQVHILPVGRIEEPFWQNFKHLQEEVFQKIKTLAQLS
KDVQDVMFYSILAMLRDRGALQDLMNMLELDSSGHLDGPGGAILKKLQQDSNHAWFNP
KDPILYLLEAIMVLSDFQHDLLACSMEKRILLQQQELVRSILEPNFRYPWSIPFTLKP
ELLAPLQSEGLAITYGLLEECGLRTELDNPRSTWDVEAKMPLSALYGTLSLLQQLAEA
"
BASE COUNT 635 a 511 c 547 g 594 t
ORIGIN
1 attgatctgg tcctggagtt tgtctgacaa tttctacttg accgcaggag gtctgaagat
61 tggaaggggc cctactcaat tgtgctattt ttctctcttc tttttttttt ttgagacgga
121 gttgcccagg ctggagtgca gcggcatggt ctcagctcac tgcaacctct gcctcccggg
181 ttcaagcagt tctctgcctc agcctcccaa gtagctggga ttacaggtgc ctgccaccat
241 tcctggctaa tttttgtatt ttcagtagag acagggtttc accatcttgg cctggctgat
301 cttgaactcc tgacctcggg atccaccggc ctcagcctcc caaagtgctg ggattacaga
361 cgtgagccac cgtgcccggc caatcctgct atttctctac aggacaaagg gatatataat
421 ctgcaacatg ccctccatgt tggaacgcat tagcaaaaat ttggtcaaag agattggaag
481 caaagacctg acatctgtca aatacctatt gagtgccacc aaattacgtc agtttgttat
541 attacgaaag aagaaggatt ctcgttcatc attttgggaa caatctgact atgttccagt
601 tgaattctcc ctcaatgaca tcctggagcc aagttcttca gtcctagaaa ctgttgtgac
661 aggaccgttc cacttcagtg acattatgat ccagaagcat aaggctgaca tgggtgtgaa
721 tgttggtata gaagtgagtg tgtcagggga ggcctctgtg gaccatggat gctccctcga
781 gtttcaaatt gttaccatcc catcaccaaa cctggaagac tttcaaaaaa ggaaactgtt
841 ggatccagag ccatcatttc tgaaggagtg ccggaggaga ggggacaacc tgtacgtggt
901 gacagaggct gttgaactga tcaacaatac tgtgctgtac gatagcagta gtgtgaatat
961 tttagggaaa attgctcttt ggattaccta tggcaagggt caaggccaag gagagagtct
1021 cagagtgaag aagaaggcgc tgactcttca gaaaggcatg gtgatggctt ataagagaaa
1081 gcagctggtt atcaaggaga aagccattct catctcagat gatgatgaac agagaacctt
1141 tcaagatgag tacgaaattt ccgaaatggt aggctactgt gctgcgagga gtgaggggtt
1201 gctaccatca tttcatacca tctctccaac cctcttcaat gcctcatcca atgatatgaa
1261 gttaaaacca gagctatttc tgacacagca atttttgagc gggcatttgc caaaatacga
1321 acaagttcac atcctcccag taggaagaat agaggaaccc ttctggcaaa atttcaagca
1381 tctacaagag gaggttttcc agaaaataaa gacactggct cagctctcaa aggatgttca
1441 ggatgtcatg ttctacagta tcctggccat gctcagagac agaggggctc tacaggacct
1501 gatgaacatg ctggaattgg acagctcagg tcatttggat ggccctggtg gtgccatcct
1561 aaagaaactt caacaggatt caaaccatgc atggtttaac ccaaaggacc ccattcttta
1621 tctccttgaa gccataatgg tgctgagtga cttccaacac gatttgctgg cctgttccat
1681 ggagaagagg atcctgcttc agcaacagga gctggtaagg agcatcctgg agccaaactt
1741 cagatacccc tggagcattc ccttcaccct caaacctgag ctcctcgccc cactccagag
1801 tgagggtttg gccatcacct atggcctgct ggaggagtgt ggccttagga cggagctgga
1861 taaccccagg tcaacctggg atgtagaagc aaagatgccc ctgtctgccc tctatgggac
1921 tctctcattg ctgcagcagc tggctgaggc ctaagccctc cctgatgggc agtcagtcca
1981 gagatgctgg ccctcgccca gtctatgctg tgagtgtcct tatgggtgca agagataggg
2041 ctgtgcctct ctgcgtttcc aggtggagta gagacagtaa tgggtagaga ctttaggaaa
2101 tgttttgggg tggtggaata ctctatatat tgacaagagt ttatatattg acaagagttt
2161 atatatttgt caaaactcct caaatagtat gttaaagacg taagcgtttc actatgtata
2221 aattttactt caaaataata aaaacaaata ctgactctaa aaaaaaaaaa aaaaaaaaaa
2281 aaaaaaa
//