LOCUS       AAH35321.1               508 aa    PRT              HUM 04-AUG-2008
DEFINITION  Homo sapiens gasdermin C protein.
ACCESSION   BC035321-1
PROTEIN_ID  AAH35321.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2287)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 2287)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2002) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: James Cleaver, M.D.
            cDNA Library Preparation: Life Technologies, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Baylor College of Medicine Human Genome
            Sequencing Center
            Center code: BCM-HGSC
            Web site: http://www.hgsc.bcm.tmc.edu/cdna/
            Contact: amg@bcm.tmc.edu
            Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
            Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
            A.N., Gibbs, R.A.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 28 Row: p Column: 22
            This clone grew slowly and was rescued by PCR.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000093825"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:21665 IMAGE:4753282"
                     /tissue_type="Skin, squamous cell carcinoma"
                     /clone_lib="NCI_CGAP_Skn4"
                     /lab_host="DH10B"
                     /note="Vector: pCMV-SPORT6.1"
     protein         /gene="GSDMC"
                     /gene_synonym="MLZE"
                     /db_xref="GeneID:56169"
                     /db_xref="HGNC:HGNC:7151"
                     /db_xref="MIM:608384"
BEGIN
        1 MPSMLERISK NLVKEIGSKD LTSVKYLLSA TKLRQFVILR KKKDSRSSFW EQSDYVPVEF
       61 SLNDILEPSS SVLETVVTGP FHFSDIMIQK HKADMGVNVG IEVSVSGEAS VDHGCSLEFQ
      121 IVTIPSPNLE DFQKRKLLDP EPSFLKECRR RGDNLYVVTE AVELINNTVL YDSSSVNILG
      181 KIALWITYGK GQGQGESLRV KKKALTLQKG MVMAYKRKQL VIKEKAILIS DDDEQRTFQD
      241 EYEISEMVGY CAARSEGLLP SFHTISPTLF NASSNDMKLK PELFLTQQFL SGHLPKYEQV
      301 HILPVGRIEE PFWQNFKHLQ EEVFQKIKTL AQLSKDVQDV MFYSILAMLR DRGALQDLMN
      361 MLELDSSGHL DGPGGAILKK LQQDSNHAWF NPKDPILYLL EAIMVLSDFQ HDLLACSMEK
      421 RILLQQQELV RSILEPNFRY PWSIPFTLKP ELLAPLQSEG LAITYGLLEE CGLRTELDNP
      481 RSTWDVEAKM PLSALYGTLS LLQQLAEA
//