LOCUS       BC024272                1155 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens CD74 molecule, major histocompatibility complex, class
            II invariant chain, mRNA (cDNA clone MGC:39144 IMAGE:4763768),
            complete cds.
ACCESSION   BC024272
VERSION     BC024272.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1155)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 1155)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-FEB-2002) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Louis Staudt
            cDNA Library Preparation: Rubin Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Genome Sequence Centre,
            BC Cancer Agency, Vancouver, BC, Canada
            info@bcgsc.bc.ca
            Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
            Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
            Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
            Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
            Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
            Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
            Kim MacDonald,  Mike R. Mayo, Josh Moran, Diana Palmquist, JR
            Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
            Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 42 Row: g Column: 4
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 68448543.
FEATURES             Location/Qualifiers
     source          1..1155
                     /db_xref="H-InvDB:HIT000039801"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:39144 IMAGE:4763768"
                     /tissue_type="Primary B-Cells from Tonsils"
                     /clone_lib="NIH_MGC_48"
                     /lab_host="DH10B-R"
                     /note="Vector: pOTB7"
     gene            1..1155
                     /gene="CD74"
                     /gene_synonym="HLADG"
                     /gene_synonym="Ia-GAMMA"
                     /gene_synonym="protein 41"
                     /db_xref="GeneID:972"
                     /db_xref="HGNC:HGNC:1697"
                     /db_xref="MIM:142790"
     CDS             21..503
                     /gene="CD74"
                     /gene_synonym="HLADG"
                     /gene_synonym="Ia-GAMMA"
                     /gene_synonym="protein 41"
                     /codon_start=1
                     /product="CD74 molecule, major histocompatibility complex,
                     class II invariant chain"
                     /protein_id="AAH24272.1"
                     /db_xref="GeneID:972"
                     /db_xref="HGNC:HGNC:1697"
                     /db_xref="MIM:142790"
                     /translation="MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKC
                     SRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRMKLPKPPK
                     PVSKMRMATPLLMQALPMGALPQGPMQNATKYGNMTEDHVMHLLQSHWNWRTRLLGWV
                     "
BASE COUNT          277 a          383 c          284 g          211 t
ORIGIN      
        1 ccggggggtc agggtcccag atgcacagga ggagaagcag gagctgtcgg gaagatcaga
       61 agccagtcat ggatgaccag cgcgacctta tctccaacaa tgagcaactg cccatgctgg
      121 gccggcgccc tggggccccg gagagcaagt gcagccgcgg agccctgtac acaggctttt
      181 ccatcctggt gactctgctc ctcgctggcc aggccaccac cgcctacttc ctgtaccagc
      241 agcagggccg gctggacaaa ctgacagtca cctcccagaa cctgcagctg gagaacctgc
      301 gcatgaagct tcccaagcct cccaagcctg tgagcaagat gcgcatggcc accccgctgc
      361 tgatgcaggc gctgcccatg ggagccctgc cccaggggcc catgcagaat gccaccaagt
      421 atggcaacat gacagaggac catgtgatgc acctgctcca gagtcactgg aactggagga
      481 cccgtcttct gggctgggtg tgaccaagca ggatctgggc ccagtcccca tgtgagagca
      541 gcagaggcgg tcttcaacat cctgccagcc ccacacagct acagctttct tgctcccttc
      601 agcccccagc ccctccccca tctcccaccc tgtacctcat cccatgagac cctggtgcct
      661 ggctctttcg tcacccttgg acaagacaaa ccaagtcgga acagcagata acaatgcagc
      721 aaggccctgc tgcccaatct ccatctgtca acaggggcgt gaggtcccag gaagtggcca
      781 aaagctagac agatccccgt tcctgacatc acagcagcct ccaacacaag gctccaagac
      841 ctaggctcat ggacgagatg ggaaggcaca gggagaaggg ataaccctac acccagaccc
      901 caggctggac atgctgactg tcctctcccc tccagccttt ggccttggct tttctagcct
      961 atttacctgc aggctgagcc actctcttcc ctttccccag catcactccc caaggaagag
     1021 ccaatgtttt ccacccataa tcctttctgc cgacccctag ttccctctgc tcagccaagc
     1081 ttgttatcag ctttcagggc catggttcac attagaataa aaggtagtaa ttagaacaaa
     1141 aaaaaaaaaa aaaaa
//