LOCUS       BC004147                1498 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens lysozyme (renal amyloidosis), mRNA (cDNA clone
            MGC:2337 IMAGE:2959387), complete cds.
ACCESSION   BC004147
VERSION     BC004147.2
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1498)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 1498)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-MAR-2001) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     On Oct 8, 2003 this sequence version replaced BC004147.1.
            Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: ATCC
            cDNA Library Preparation: Rubin Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Institute for Systems Biology
            http://www.systemsbiology.org
            contact: amadan@systemsbiology.org
            Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
            Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 2 Row: g Column: 16
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 4557893.
FEATURES             Location/Qualifiers
     source          1..1498
                     /db_xref="H-InvDB:HIT000031733"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:2337 IMAGE:2959387"
                     /tissue_type="Colon, adenocarcinoma"
                     /clone_lib="NIH_MGC_15"
                     /lab_host="DH10B-R"
                     /note="Vector: pOTB7"
     gene            1..1498
                     /gene="LYZ"
                     /db_xref="GeneID:4069"
                     /db_xref="HGNC:HGNC:6740"
                     /db_xref="MIM:153450"
     CDS             20..466
                     /gene="LYZ"
                     /codon_start=1
                     /product="lysozyme (renal amyloidosis)"
                     /protein_id="AAH04147.1"
                     /db_xref="GeneID:4069"
                     /db_xref="HGNC:HGNC:6740"
                     /db_xref="MIM:153450"
                     /translation="MKALIVLGLVLLSVTVQGKVFERCELARTLKRLGMDGYRGISLA
                     NWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSAL
                     LQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV"
BASE COUNT          451 a          303 c          307 g          437 t
ORIGIN      
        1 ctctgaccta gcagtcaaca tgaaggctct cattgttctg gggcttgtcc tcctttctgt
       61 tacggtccag ggcaaggtct ttgaaaggtg tgagttggcc agaactctga aaagattggg
      121 aatggatggc tacaggggaa tcagcctagc aaactggatg tgtttggcca aatgggagag
      181 tggttacaac acacgagcta caaactacaa tgctggagac agaagcactg attatgggat
      241 atttcagatc aatagccgct actggtgtaa tgatggcaaa accccaggag cagttaatgc
      301 ctgtcattta tcctgcagtg ctttgctgca agataacatc gctgatgctg tagcttgtgc
      361 aaagagggtt gtccgtgatc cacaaggcat tagagcatgg gtggcatgga gaaatcgttg
      421 tcaaaacaga gatgtccgtc agtatgttca aggttgtgga gtgtaactcc agaattttcc
      481 ttcttcagct cattttgtct ctctcacatt aagggagtag gaattaagtg aaaggtcaca
      541 ctaccattat ttccccttca aacaaataat atttttacag aagcaggagc aaaatatggc
      601 ctttcttcta agagatataa tgttcactaa tgtggttatt ttatattaag cctacaacat
      661 ttttcagttt gcaaatagaa ctaatactgg tgaaaattta cctaaaacct tggttatcaa
      721 atacatctcc agtacattcc gttctttttt tttttgagac agtctcgctc tgtcgcccag
      781 gctggagtgc agtggcgcaa tctcggctca ctgcaacctc cacctcccgg gttcacgcca
      841 ttctcctgcc tcagcctccc gagtagctgg gattacgggc gcccgccacc acgcccggct
      901 aattttttgt atttttagta gagacagggt ttcaccgtgt tagccaggat ggtctcgatc
      961 tcctgacctt gtgatccacc cacctcggcc tcccaaagtg ctgggattac aggcgtgagc
     1021 cactgcgccc ggccacattc agttcttatc aaagaaataa cccagactta atcttgaatg
     1081 atacgattat gcccaatatt aagtaaaaaa tataagaaaa ggttatctta aatagatctt
     1141 aggcaaaata ccagctgatg aaggcatctg atgccttcat ctgttcagtc atctccaaaa
     1201 acagtaaaaa taaccacttt ttgttgggca atatgaaatt tttaaaggag tagaatacca
     1261 aatgatagaa acagactgcc tgaattgaga attttgattt cttaaagtgt gtttctttct
     1321 aaattgctgt tccttaattt gattaattta attcatgtat tatgattaaa tctgaggcag
     1381 atgagcttac aagtattgaa ataattacta attaatcaca aatgtgaagt tatgcatgat
     1441 gtaaaaaata caaacattct aattaaaggc tttgcaacac aaaaaaaaaa aaaaaaaa
//