LOCUS       BC001063                1079 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens high-mobility group box 2, mRNA (cDNA clone MGC:2393
            IMAGE:2963045), complete cds.
ACCESSION   BC001063
VERSION     BC001063.2
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1079)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 1079)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2000) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     On Aug 19, 2003 this sequence version replaced BC001063.1.
            Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: ATCC
            cDNA Library Preparation: Rubin Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Institute for Systems Biology
            http://www.systemsbiology.org
            contact: amadan@systemsbiology.org
            Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
            Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 2 Row: l Column: 16
            This clone was selected for full length sequencing because it
            passed the following selection criteria: Hexamer frequency ORF
            analysis, Similarity but not identity to protein.
FEATURES             Location/Qualifiers
     source          1..1079
                     /db_xref="H-InvDB:HIT000030113"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:2393 IMAGE:2963045"
                     /tissue_type="Placenta, choriocarcinoma"
                     /clone_lib="NIH_MGC_21"
                     /lab_host="DH10B-R"
                     /note="Vector: pOTB7"
     gene            1..1079
                     /gene="HMGB2"
                     /db_xref="GeneID:3148"
                     /db_xref="HGNC:HGNC:5000"
                     /db_xref="MIM:163906"
     CDS             54..683
                     /gene="HMGB2"
                     /codon_start=1
                     /product="high-mobility group box 2"
                     /protein_id="AAH01063.1"
                     /db_xref="GeneID:3148"
                     /db_xref="HGNC:HGNC:5000"
                     /db_xref="MIM:163906"
                     /translation="MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKK
                     CSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAF
                     FLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIA
                     AYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEEEEDEDEEEEDEDEE"
BASE COUNT          373 a          177 c          264 g          265 t
ORIGIN      
        1 ctctgcggga ctctgaggaa aagctcgcac caggtggacg cggatctgtc aacatgggta
       61 aaggagaccc caacaagccg cggggcaaaa tgtcctcgta cgccttcttc gtgcagacct
      121 gccgggaaga gcacaagaag aaacacccgg actcttccgt caatttcgcg gaattctcca
      181 agaagtgttc ggagagatgg aagaccatgt ctgcaaagga gaagtcgaag tttgaagata
      241 tggcaaaaag tgacaaagct cgctatgaca gggagatgaa aaattacgtt cctcccaaag
      301 gtgataagaa ggggaagaaa aaggacccca atgctcctaa aaggccacca tctgccttct
      361 tcctgttttg ctctgaacat cgcccaaaga tcaaaagtga acaccctggc ctatccattg
      421 gggatactgc aaagaaattg ggtgaaatgt ggtctgagca gtcagccaaa gataaacaac
      481 catatgaaca gaaagcagct aagctaaagg agaaatatga aaaggatatt gctgcatatc
      541 gtgccaaggg caaaagtgaa gcaggaaaga agggccctgg caggccaaca ggctcaaaga
      601 agaagaacga accagaagat gaggaggagg aggaggaaga agaagatgaa gatgaggagg
      661 aagaggatga agatgaagaa taaatggcta tcctttaatg atgcgtgtgg aatgtgtgtg
      721 tgtgctcagg caattatttt gctaagaatg tgaattcaag tgcagctcaa tactagcttc
      781 agtataaaaa ctgtacagat ttttgtatag ctgataagat tctctgtaga gaaaatactt
      841 ttaaaaaatg caggttgtag ctttttgatg ggctactcat acagttagat tttacagctt
      901 ctgatgttga atgttcctaa atatttaatg gtttttttaa tttcttgtgt atggtagcac
      961 agcaaacttg taggaattag tatcaatagt aaattttggg ttttttagga tgttgcattt
     1021 cgttttttta aaaaaaattt tgtaataaaa ttatgtatat taaaaaaaaa aaaaaaaaa
//