LOCUS       BC000594                3413 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens lysyl oxidase-like 2, mRNA (cDNA clone MGC:1709
            IMAGE:3347512), complete cds.
ACCESSION   BC000594
VERSION     BC000594.2
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3413)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 3413)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-NOV-2000) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     On Aug 19, 2003 this sequence version replaced BC000594.1.
            Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: DCTD/DTP
            cDNA Library Preparation: Rubin Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: National Institutes of Health Intramural
            Sequencing Center (NISC),
            Gaithersburg, Maryland;
            Web site: http://www.nisc.nih.gov/
            Contact: nisc_mgc@nhgri.nih.gov
            Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
            Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
            Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
            Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
            Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
            McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
            Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
            Young,A., Zhang,L.-H. and Green,E.D.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 5 Row: a Column: 24
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 67782347.
FEATURES             Location/Qualifiers
     source          1..3413
                     /db_xref="H-InvDB:HIT000029761"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:1709 IMAGE:3347512"
                     /tissue_type="Kidney, renal cell adenocarcinoma"
                     /clone_lib="NIH_MGC_14"
                     /lab_host="DH10B-R"
                     /note="Vector: pOTB7"
     gene            1..3413
                     /gene="LOXL2"
                     /gene_synonym="LOR2"
                     /gene_synonym="WS9-14"
                     /db_xref="GeneID:4017"
                     /db_xref="HGNC:HGNC:6666"
                     /db_xref="MIM:606663"
     CDS             210..2534
                     /gene="LOXL2"
                     /gene_synonym="LOR2"
                     /gene_synonym="WS9-14"
                     /codon_start=1
                     /product="lysyl oxidase-like 2"
                     /protein_id="AAH00594.1"
                     /db_xref="GeneID:4017"
                     /db_xref="HGNC:HGNC:6666"
                     /db_xref="MIM:606663"
                     /translation="MERPLCSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEY
                     HQPQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGY
                     VEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSD
                     KRIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQIC
                     DKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCK
                     LGPQVSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYI
                     GEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNE
                     IQCTGNEKSIIDCKFNAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEV
                     LVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSG
                     VKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDR
                     PMFLLQCAMEENCLSASAAQTDPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHD
                     CHRHYHSMEVFTHYDLLNLNGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGIT
                     MGCWDMYRHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHR
                     IWMYNCHIGGSFSEETEKKFEHFSGLLNNQLSPQ"
BASE COUNT          788 a          996 c          974 g          655 t
ORIGIN      
        1 ctccagccat cggagaccag agccgccccc tctgctcgag aaaggggctc agcggcggcg
       61 gaagcggagg gggaccaccg tggagagcgc ggtcccagcc cggccactgc ggatccctga
      121 aaccaaaaag ctcctgctgc ttctgtaccc cgcctgtccc tcccagctgc gcagggcccc
      181 ttcgtgggat catcagcccg aagacaggga tggagaggcc tctgtgctcc cacctctgca
      241 gctgcctggc tatgctggcc ctcctgtccc ccctgagcct ggcacagtat gacagctggc
      301 cccattaccc cgagtacttc cagcaaccgg ctcctgagta tcaccagccc caggcccccg
      361 ccaacgtggc caagattcag ctgcgcctgg ctgggcagaa gaggaagcac agcgagggcc
      421 gggtggaggt gtactatgat ggccagtggg gcaccgtgtg cgatgacgac ttctccatcc
      481 acgctgccca cgtcgtctgc cgggagctgg gctacgtgga ggccaagtcc tggactgcca
      541 gctcctccta cggcaaggga gaagggccca tctggttaga caatctccac tgtactggca
      601 acgaggcgac ccttgcagca tgcacctcca atggctgggg cgtcactgac tgcaagcaca
      661 cggaggatgt cggtgtggtg tgcagcgaca aaaggattcc tgggttcaaa tttgacaatt
      721 cgttgatcaa ccagatagag aacctgaata tccaggtgga ggacattcgg attcgagcca
      781 tcctctcaac ctaccgcaag cgcaccccag tgatggaggg ctacgtggag gtgaaggagg
      841 gcaagacctg gaagcagatc tgtgacaagc actggacggc caagaattcc cgcgtggtct
      901 gcggcatgtt tggcttccct ggggagagga catacaatac caaagtgtac aaaatgtttg
      961 cctcacggag gaagcagcgc tactggccat tctccatgga ctgcaccggc acagaggccc
     1021 acatctccag ctgcaagctg ggcccccagg tgtcactgga ccccatgaag aatgtcacct
     1081 gcgagaatgg gctaccggcc gtggtgagtt gtgtgcctgg gcaggtcttc agccctgacg
     1141 gaccctcgag attccggaaa gcgtacaagc cagagcaacc cctggtgcga ctgagaggcg
     1201 gtgcctacat cggggagggc cgcgtggagg tgctcaaaaa tggagagtgg gggaccgtct
     1261 gcgacgacaa gtgggacctg gtgtcggcca gtgtggtctg cagagagctg ggctttggga
     1321 gtgccaaaga ggcagtcact ggctcccgac tggggcaagg gatcggaccc atccacctca
     1381 acgagatcca gtgcacaggc aatgagaagt ccattataga ctgcaagttc aatgccgagt
     1441 ctcagggctg caaccacgag gaggatgctg gtgtgagatg caacacccct gccatgggct
     1501 tgcagaagaa gctgcgcctg aacggcggcc gcaatcccta cgagggccga gtggaggtgc
     1561 tggtggagag aaacgggtcc cttgtgtggg ggatggtgtg tggccaaaac tggggcatcg
     1621 tggaggccat ggtggtctgc cgccagctgg gcctgggatt cgccagcaac gccttccagg
     1681 agacctggta ttggcacgga gatgtcaaca gcaacaaagt ggtcatgagt ggagtgaagt
     1741 gctcgggaac ggagctgtcc ctggcgcact gccgccacga cggggaggac gtggcctgcc
     1801 cccagggcgg agtgcagtac ggggccggag ttgcctgctc agaaaccgcc cctgacctgg
     1861 tcctcaatgc ggagatggtg cagcagacca cctacctgga ggaccggccc atgttcctgc
     1921 tgcagtgtgc catggaggag aactgcctct cggcctcagc cgcgcagacc gaccccacca
     1981 cgggctaccg ccggctcctg cgcttctcct cccagatcca caacaatggc cagtccgact
     2041 tccggcccaa gaacggccgc cacgcgtgga tctggcacga ctgtcacagg cactaccaca
     2101 gcatggaggt gttcacccac tatgacctgc tgaacctcaa tggcaccaag gtggcagagg
     2161 gccacaaggc cagcttctgc ttggaggaca cagaatgtga aggagacatc cagaagaatt
     2221 acgagtgtgc caacttcggc gatcagggca tcaccatggg ctgctgggac atgtaccgcc
     2281 atgacatcga ctgccagtgg gttgacatca ctgacgtgcc ccctggagac tacctgttcc
     2341 aggttgttat taaccccaac ttcgaggttg cagaatccga ttactccaac aacatcatga
     2401 aatgcaggag ccgctatgac ggccaccgca tctggatgta caactgccac ataggtggtt
     2461 ccttcagcga agagacggaa aaaaagtttg agcacttcag cgggctctta aacaaccagc
     2521 tgtccccgca gtaaagaagc ctgcgtggtc aactcctgtc ttcaggccac accacatctt
     2581 ccatgggact tccccccaac aactgagtct gaacgaatgc cacgtgccct cacccagccc
     2641 ggcccccacc ctgtccagac ccctacagct gtgtctaagc tcaggaggaa agggaccctc
     2701 ccatcattca tggggggctg ctacctgacc cttggggcct gagaaggcct tgggggggtg
     2761 gggtttgtcc acagagctgc tggagcagca ccaagagcca gtcttgaccg ggatgaggcc
     2821 cacagacagg ttgtcatcag cttgtcccat tcaagccacc gagctcacca cagacacagt
     2881 ggagccgcgc tcttctccag tgacacgtgg acaaatgcgg gctcatcagc ccccccagag
     2941 agggtcaggc cgaaccccat ttctcctcct cttaggtcat tttcagcaaa cttgaatatc
     3001 tagacctctc ttccaatgaa accctccagt ctattatagt cacatagata atggtgccac
     3061 gtgttttctg atttggtgag ctcagacttg gtgcttccct ctccacaacc cccacccctt
     3121 gtttttcaag atactattat tatattttca cagacttttg aagcacaaat ttattggcat
     3181 ttaatattgg acatctgggc ccttggaagt acaaatctaa ggaaaaacca acccactgtg
     3241 taagtgactc atcttcctgt tgttccaatt ctgtgggttt ttgattcaac ggtgctataa
     3301 ccagggtcct gggtgacagg gcgctcactg agcaccatgt gtcatcacag acacttacac
     3361 atacttgaaa cttggaataa aagaaagatt tatgaaaaaa aaaaaaaaaa aaa
//