LOCUS       BC067822                1677 bp    mRNA    linear   HUM 17-JUL-2006
DEFINITION  Homo sapiens 3-hydroxyisobutyryl-Coenzyme A hydrolase, mRNA (cDNA
            clone MGC:87353 IMAGE:5266813), complete cds.
ACCESSION   BC067822
VERSION     BC067822.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1677)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 1677)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-MAR-2004) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
            cDNA Library Preparation: Michael J. Brownstein (NHGRI) &  Shiraki
            Toshiyuki and Piero Carninci (RIKEN)
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:       http://www-shgc.stanford.edu
            Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 167 Row: l Column: 5
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 37594468.
FEATURES             Location/Qualifiers
     source          1..1677
                     /db_xref="H-InvDB:HIT000262790"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:87353 IMAGE:5266813"
                     /tissue_type="Testis"
                     /clone_lib="NIH_MGC_97"
                     /lab_host="DH10B"
                     /note="Vector: pBluescriptR"
     gene            1..1677
                     /gene="HIBCH"
                     /gene_synonym="HIBYL-COA-H"
                     /db_xref="GeneID:26275"
                     /db_xref="HGNC:HGNC:4908"
     CDS             25..1185
                     /gene="HIBCH"
                     /gene_synonym="HIBYL-COA-H"
                     /codon_start=1
                     /product="3-hydroxyisobutyryl-Coenzyme A hydrolase"
                     /protein_id="AAH67822.1"
                     /db_xref="GeneID:26275"
                     /db_xref="HGNC:HGNC:4908"
                     /translation="MGQREMWRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLGKKG
                     CTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRV
                     ISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT
                     EKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVD
                     SEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANT
                     VEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQ
                     ACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF"
BASE COUNT          552 a          263 c          376 g          486 t
ORIGIN      
        1 gctttagctt cggagtgttt ggcgatgggg cagcgcgaga tgtggaggct catgtcgagg
       61 tttaatgcat tcaaaaggac taataccata ctgcaccatt tgagaatgtc caagcacaca
      121 gatgcagcag aagaggtgct attgggaaaa aaaggttgca cgggagtcat aacactaaac
      181 agaccaaagt tcctcaatgc actgactctt aatatgattc ggcagattta tccacagcta
      241 aagaagtggg aacaagatcc tgaaactttc ctgatcatta taaagggagc aggaggaaag
      301 gctttctgtg ccgggggtga tatcagagtg atctcggaag ctgaaaaggc aaaacagaag
      361 atagctccag ttttcttcag agaagaatat atgctgaata atgctgttgg ttcttgccag
      421 aaaccttatg ttgcacttat tcatggaatt acaatgggtg ggggagttgg tctctcagtc
      481 catgggcaat ttcgagtggc tacagaaaag tgtctttttg ctatgccaga aactgcaata
      541 ggactgttcc ctgatgtggg tggaggttat ttcttgccac gactccaagg aaaacttggt
      601 tacttccttg cattaacagg attcagacta aaaggaagag atgtgtacag agcaggaatt
      661 gctacacact ttgtagattc tgaaaagttg gccatgttag aggaagattt gttagccttg
      721 aaatctcctt caaaagaaaa tattgcatct gtcttagaaa attaccatac agagtctaag
      781 attgatcgag acaagtcttt tatacttgag gaacacatgg acaaaataaa cagttgtttt
      841 tcagccaata ctgtggaaga aattattgaa aacttacagc aagatggttc atcttttgcc
      901 ctagagcaat tgaaggtaat taataaaatg tctccaacat ctctaaagat cacactaagg
      961 caactcatgg aggggtcttc aaagaccttg caagaagtac taactatgga gtatcggcta
     1021 agtcaagctt gtatgagagg tcatgacttt catgaaggcg ttagagctgt tttaattgat
     1081 aaagaccaga gtccaaaatg gaaaccagct gatctaaaag aagttactga ggaagatttg
     1141 aataatcact ttaagtcttt gggaagcagt gatttgaaat tttgaagtga caggctttta
     1201 aggtatattt tgtagcatgg gttggcaatc tacagcatgt gggccaaatc cagcctgctg
     1261 cctgttttta tataccctgt aagctaagaa tggtttccgc atttttaaat ggttgggaaa
     1321 agaaatcaaa gactaatatt tcatgacgtg aaaattatca gaattcacaa ataaagcttt
     1381 attggaacta gctatactca tctgtttata tattatctgt ggctgctttg aaatgagtag
     1441 ttgcaataga gatggtaaag cctacaaagc ctaattattt actgtctggt ttttgtcaga
     1501 aaaaagtttg tcaatccttg ttttagaaga tggaaaaatg tgaagatctt tagagattct
     1561 cttgagtggt atatctaatt gaaatgggat ctttgtttgg cttgtatgtt gatgaaatca
     1621 acttaggtat acaatataaa aaataaagac cctgaaaatt gaaaaaaaaa aaaaaaa
//