LOCUS BC066876 1349 bp mRNA linear HUM 02-MAR-2004
DEFINITION Homo sapiens UDP-GlcNAc:betaGal
beta-1,3-N-acetylglucosaminyltransferase 3, mRNA (cDNA clone
MGC:79245 IMAGE:6971715), complete cds.
ACCESSION BC066876
VERSION BC066876.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1349)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1349)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Narayan Bhat
cDNA Library Preparation: Bhat Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 172 Row: c Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 15451894.
FEATURES Location/Qualifiers
source 1..1349
/db_xref="H-InvDB:HIT000262297"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:79245 IMAGE:6971715"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_195"
/lab_host="DH10B"
/note="Vector: pDNR-Dual"
gene 1..1349
/gene="B3GNT3"
/gene_synonym="B3GAL-T8"
/gene_synonym="B3GN-T3"
/gene_synonym="B3GNT-3"
/gene_synonym="beta3Gn-T3"
/gene_synonym="HP10328"
/gene_synonym="TMEM3"
/db_xref="GeneID:10331"
/db_xref="MIM:605863"
CDS 120..1238
/gene="B3GNT3"
/gene_synonym="B3GAL-T8"
/gene_synonym="B3GN-T3"
/gene_synonym="B3GNT-3"
/gene_synonym="beta3Gn-T3"
/gene_synonym="HP10328"
/gene_synonym="TMEM3"
/codon_start=1
/product="B3GNT3 protein"
/protein_id="AAH66876.1"
/db_xref="GeneID:10331"
/db_xref="MIM:605863"
/translation="MKYLRHRRPNATLILAIGAFTLLLFSLLVSPPTCKVQEQPPAIP
EALAWPTPPTRPAPAPCHANTSMVTHPDFATQPQHVQNFLLYRHYRHFPLLQDVPPSK
CAQPVFLLLVIKSSPSNYVRRELLRRTWGRERKVRGLQLRLLFLVGTASNPHEARKVN
RLLELEAQTHGDILQWDFHDSFFNLTLKQVLFLQWQETRCANASFVLNGDDDVFAHTD
NMVFYLQDHDPGRHLFVGQLIQNVGPIRAFWSKYYVPEVVTQNERYPPYCGGGGFLLS
RFTAAALRRAAHVLDIFPIDDVFLGMCLELEGLKPASHSGIRTSGVRAPSQHLSSFDP
CFYRDLLLVHRFLPYEMLLMWDALNQPNLTCGNQTQIY"
misc_feature 483..1052
/gene="B3GNT3"
/gene_synonym="B3GAL-T8"
/gene_synonym="B3GN-T3"
/gene_synonym="B3GNT-3"
/gene_synonym="beta3Gn-T3"
/gene_synonym="HP10328"
/gene_synonym="TMEM3"
/note="Galactosyl_T; Region: Galactosyltransferase. This
family includes the galactosyltransferases
UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-
galactosyltransferase and UDP-Gal:beta-GlcNAc beta
1,3-galactosyltranferase. Specific galactosyltransferases
transfer galactose to GlcNAc terminal chains in the
synthesis of the lacto-series oligosaccharides types 1 and
2"
/db_xref="CDD:pfam01762"
BASE COUNT 240 a 463 c 372 g 274 t
ORIGIN
1 cgagctgaga ggagcaggta gaggggcaga ggcgggactg tcgtctgggg tgagttttgt
61 tttccacagg agccgcccag gaggctcctc aggccgaccc cagaccctgg ctggccagga
121 tgaagtatct ccggcaccgg cggcccaatg ccaccctcat tctggccatc ggcgctttca
181 ccctcctcct cttcagtctg ctagtgtcac cacccacctg caaggtccag gagcagccac
241 cggcgatccc cgaggccctg gcctggccca ctccacccac ccgcccagcc ccggccccgt
301 gccatgccaa cacctctatg gtcacccacc cggacttcgc cacgcagccg cagcatgttc
361 agaacttcct cctgtacaga cactaccgcc actttcccct gctgcaggac gtgcccccct
421 ctaagtgcgc gcagccggtc ttcctgctgc tggtgatcaa gtcctcccct agcaactatg
481 tgcgccgcga gctgctgcgg cgcacgtggg gccgcgagcg caaggtacgg ggtttgcagc
541 tgcgcctcct cttcctggtg ggtacagcct ccaacccgca cgaggcccgc aaggtcaacc
601 ggctgctgga gctggaggca cagactcacg gagacatcct gcagtgggac ttccacgact
661 ccttcttcaa cctcacgctc aagcaggtcc tgttcttaca gtggcaggag acaaggtgcg
721 ccaacgccag cttcgtgctc aacggggatg atgacgtctt tgcacacaca gacaacatgg
781 tcttctacct gcaggaccat gaccctggcc gccacctctt cgtggggcaa ctgatccaaa
841 acgtgggccc catccgggct ttttggagca agtactatgt gccagaggtg gtgactcaga
901 atgagcggta cccaccctat tgtgggggtg gtggcttctt gctgtcccgc ttcacggccg
961 ctgccctgcg ccgtgctgcc catgtcttgg acatcttccc cattgatgat gtcttcctgg
1021 gtatgtgtct ggagcttgag ggactgaagc ctgcctccca cagcggcatc cgcacgtctg
1081 gcgtgcgggc tccatcgcaa cacctgtcct cctttgaccc ctgcttctac cgagacctgc
1141 tgctggtgca ccgcttccta ccttatgaga tgctgctcat gtgggatgcg ctgaaccagc
1201 ccaacctcac ctgcggcaat cagacacaga tctactgagt cagcatcagg gtccccagcc
1261 tctgggctcc tgtttccata ggaaggggcg acaccttcct cccaggaaac tgagaccttt
1321 gtggtctgag cataagggag tgccaggga
//