LOCUS       BC066264                 599 bp    mRNA    linear   HUM 08-MAR-2005
DEFINITION  Homo sapiens interleukin 22, mRNA (cDNA clone MGC:79383
            IMAGE:6971855), complete cds.
ACCESSION   BC066264
VERSION     BC066264.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
            Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
            B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
            Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
            GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
            Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
            Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
            SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
            Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
            Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
            Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
            Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
            Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
            Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
            Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 599)
  AUTHORS   Director MGC Project.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-FEB-2004) National Institutes of Health, Mammalian
            Gene Collection (MGC), Cancer Genomics Office, National Cancer
            Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
            USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Narayan Bhat
            cDNA Library Preparation: Bhat Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:       http://www-shgc.stanford.edu
            Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 172 Row: d Column: 9
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 41393566.
FEATURES             Location/Qualifiers
     source          1..599
                     /db_xref="H-InvDB:HIT000262159"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:79383 IMAGE:6971855"
                     /tissue_type="PCR rescued clones"
                     /clone_lib="NIH_MGC_195"
                     /lab_host="DH10B"
                     /note="Vector: pDNR-Dual"
     gene            1..599
                     /gene="IL22"
                     /gene_synonym="IL-21"
                     /gene_synonym="IL-22"
                     /gene_synonym="IL-D110"
                     /gene_synonym="IL-TIF"
                     /gene_synonym="IL21"
                     /gene_synonym="ILTIF"
                     /gene_synonym="TIFa"
                     /gene_synonym="TIFIL-23"
                     /gene_synonym="zcyto18"
                     /db_xref="GeneID:50616"
                     /db_xref="MIM:605330"
     CDS             50..589
                     /gene="IL22"
                     /gene_synonym="IL-21"
                     /gene_synonym="IL-22"
                     /gene_synonym="IL-D110"
                     /gene_synonym="IL-TIF"
                     /gene_synonym="IL21"
                     /gene_synonym="ILTIF"
                     /gene_synonym="TIFa"
                     /gene_synonym="TIFIL-23"
                     /gene_synonym="zcyto18"
                     /codon_start=1
                     /product="interleukin 22"
                     /protein_id="AAH66264.1"
                     /db_xref="GeneID:50616"
                     /db_xref="MIM:605330"
                     /translation="MAALQKSVSSFLMGTLATSCLLLLALLVQGGAAAPISSHCRLDK
                     SNFQQPYITNRTFMLAKEASLADNNTDVRLIGEKLFHGVSMSERCYLMKQVLNFTLEE
                     VLFPQSDRFQPYMQEVVPFLARLSNRLSTCHIEGDDLHIQRNVQKLKDTVKKLEESGE
                     IKAIGELDLLFMSLRNACI"
BASE COUNT          150 a          154 c          152 g          143 t
ORIGIN      
        1 acagttctcc ttccccagtc accagttgct cgagttagaa ttgtctgcaa tggccgccct
       61 gcagaaatct gtgagctctt tccttatggg gaccctggcc accagctgcc tccttctctt
      121 ggccctcttg gtacagggag gagcagctgc gcccatcagc tcccactgca ggcttgacaa
      181 gtccaacttc cagcagccct atatcaccaa ccgcaccttc atgctggcta aggaggctag
      241 cttggctgat aacaacacag acgttcgtct cattggggag aaactgttcc acggagtcag
      301 tatgagtgag cgctgctatc tgatgaagca ggtgctgaac ttcacccttg aagaagtgct
      361 gttccctcaa tctgataggt tccagcctta tatgcaggag gtggtgccct tcctggccag
      421 gctcagcaac aggctaagca catgtcatat tgaaggtgat gacctgcata tccagaggaa
      481 tgtgcaaaag ctgaaggaca cagtgaaaaa gcttgaagag agtggagaga tcaaagcaat
      541 tggagaactg gatttgctgt ttatgtctct gagaaatgcc tgcatttgac cagagcaaa
//