LOCUS BC055428 4263 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens matrix metallopeptidase 15 (membrane-inserted), mRNA
(cDNA clone MGC:51077 IMAGE:4811572), complete cds.
ACCESSION BC055428
VERSION BC055428.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4263)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4263)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 90 Row: c Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 45594662.
FEATURES Location/Qualifiers
source 1..4263
/db_xref="H-InvDB:HIT000054125"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:51077 IMAGE:4811572"
/tissue_type="Brain, hippocampus"
/clone_lib="NIH_MGC_95"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..4263
/gene="MMP15"
/gene_synonym="MT2-MMP"
/gene_synonym="MTMMP2"
/gene_synonym="SMCP-2"
/db_xref="GeneID:4324"
/db_xref="HGNC:HGNC:7161"
/db_xref="MIM:602261"
CDS 787..2796
/gene="MMP15"
/gene_synonym="MT2-MMP"
/gene_synonym="MTMMP2"
/gene_synonym="SMCP-2"
/codon_start=1
/product="matrix metallopeptidase 15 (membrane-inserted)"
/protein_id="AAH55428.1"
/db_xref="GeneID:4324"
/db_xref="HGNC:HGNC:7161"
/db_xref="MIM:602261"
/translation="MGSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLGCLGLGV
AAEDAEVHAENWLRLYGYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEET
KEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHS
MEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGF
LAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAI
MAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRP
PQPPPPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAMLRGEMFVFKGRWF
WRVRHNRVLDNYPMPIGHFWRGLPGDISAAYERQDGRFVFFKGDRYWLFREANLEPGY
PQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPGYPKPISVWQ
GIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGCQEHVEPG
PRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGAGVNKDGGSRVVVQMEEVARTV
NVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLYCKRSLQEWV"
BASE COUNT 708 a 1424 c 1375 g 756 t
ORIGIN
1 ggcgcggggt gggctggaga ggtttcctgc cgtctgggaa gcgtaaacgg accgcccacc
61 tgtcgggcct cggccgcccg cacctgcttg tgagaagcct gcggctgggg caccgccccc
121 ggtccccgcc cgggtccgcg cattgggagc acactggccc tttaagagcg cggcggccgc
181 ggcgcgcggg gaggagggct gggagcgccc ggagccgcgc tgaactcgcc ggggacgtcg
241 ggcgcccgct ccttggctgg ctcgcttgct ctctcgctcg ctctctcggg tcggctccct
301 gcgcctcctc ccgggactgc ttggggaccc gggcccggtc gggcgcggcg gcgagcagaa
361 tccccgtgca ggaggcgcgc gctccgggca gcgcccggcc ccgggcatgg acaggggagc
421 tgggcgcgca gggagcgccg cgggaccggg cggccggagc gctgagccag acaaaggctc
481 cggagttgcg cttgctctcg ggagccgggc cccaggcgct gggcgccgag gctgcggaac
541 ctcgccgggg gcagctccgg tcggccccct ttcccgccgg ctggttccga gctcccggac
601 ctgccctgcc cgcttctcct cgggcttggg aatttgccga ggcgacctag gcggctccgg
661 cggggaccgg gagcccgagg tccgcggcgc gcctgccggg ccaggagcca gggagcgtcg
721 caagtttcca aggcgcgtgc gaggatccgg cgtgcagtgt tccgagctgg gctgggcgcc
781 gagagcatgg gcagcgaccc gagcgcgccc ggacggccgg gctggacggg cagcctcctc
841 ggcgaccggg aggaggcggc gcggccgcga ctgctgccgc tgctcctggt gcttctgggc
901 tgcctgggcc ttggcgtagc ggccgaagac gcggaggtcc atgccgagaa ctggctgcgg
961 ctttatggct acctgcctca gcccagccgc catatgtcca ccatgcgttc cgcccagatc
1021 ttggcctcgg cccttgcaga gatgcagcgc ttctacggga tcccagtcac cggtgtgctc
1081 gacgaagaga ccaaggagtg gatgaagcgg ccccgctgtg gggtgccaga ccagttcggg
1141 gtacgagtga aagccaacct gcggcggcgt cggaagcgct acgccctcac cgggaggaag
1201 tggaacaacc accatctgac ctttagcatc cagaactaca cggagaagtt gggctggtac
1261 cactcgatgg aggcggtgcg cagggccttc cgcgtgtggg agcaggccac gcccctggtc
1321 ttccaggagg tgccctatga ggacatccgg ctgcggcgac agaaggaggc cgacatcatg
1381 gtactctttg cctctggctt ccacggcgac agctcgccgt ttgatggcac cggtggcttt
1441 ctggcccacg cctatttccc tggccccggc ctaggcgggg acacccattt tgacgcagat
1501 gagccctgga ccttctccag cactgacctg catggaaaca acctcttcct ggtggcagtg
1561 catgagctgg gccacgcgct ggggctggag cactccagca accccaatgc catcatggca
1621 ccgttctacc agtggaagga cgttgacaac ttcaagctgc ccgaggacga tctccgtggc
1681 atccagcagc tctacggtac cccagacggt cagccacagc ctacccagcc tctccccact
1741 gtgacgccac ggcggccagg ccggcctgac caccggccgc cccggcctcc ccagccacca
1801 cccccaggtg ggaagccaga gcggccccca aagccgggcc ctccagtcca gccccgagcc
1861 acagagcggc ccgaccagta tggccccaac atctgcgacg gggactttga cacagtggcc
1921 atgcttcgcg gggagatgtt cgtgttcaag ggccgctggt tctggcgagt ccggcacaac
1981 cgcgtcctgg acaactatcc catgcccatc gggcacttct ggcgtggtct gcccggtgac
2041 atcagtgctg cctacgagcg ccaagacggt cgttttgtct ttttcaaagg tgaccgctac
2101 tggctctttc gagaagcgaa cctggagccc ggctacccac agccgctgac cagctatggc
2161 ctgggcatcc cctatgaccg cattgacacg gccatctggt gggagcccac aggccacacc
2221 ttcttcttcc aagaggacag gtactggcgc ttcaacgagg agacacagcg tggagaccct
2281 gggtacccca agcccatcag tgtctggcag gggatccctg cctcccctaa aggggccttc
2341 ctgagcaatg acgcagccta cacctacttc tacaagggca ccaaatactg gaaattcgac
2401 aatgagcgcc tgcggatgga gcccggctac cccaagtcca tcctgcggga cttcatgggc
2461 tgccaggagc acgtggagcc aggcccccga tggcccgacg tggcccggcc gcccttcaac
2521 ccccacgggg gtgcagagcc cggggcggac agcgcagagg gcgacgtggg ggatggggat
2581 ggggactttg gggccggggt caacaaggac gggggcagcc gcgtggtggt gcagatggag
2641 gaggtggcac ggacggtgaa cgtggtgatg gtgctggtgc cactgctgct gctgctctgc
2701 gtcctgggcc tcacctacgc gctggtgcag atgcagcgca agggtgcgcc acgtgtcctg
2761 ctttactgca agcgctcgct gcaggagtgg gtctgaccac ccagcgctcc tgctaacggt
2821 gctcaggggg cgcctgtggt tctgagatgg ctcccagggg ctccctccgc ccccaggtag
2881 gggcccctct cagccctcac acaccctgtc tgccccgccc tcattattta tgtccaggtg
2941 tttgttttgt tttgtttttg gcaccttact tgaccatttg tttctgtttc cccgactggg
3001 gcagggtgtt tagaattttc taaatgtagt tctgctccag acagggaatt aggcccccat
3061 catcctctgg cttggccaca gccaggggag cagaggggca gaggcccaca ttggaagagc
3121 agcacctcct cagcctgaac cccagggctg taactgccag gctctctttg cccagttgga
3181 gactgtctgg cccccctggt cccctccttc ccaagtgagt ctctctgggc cttaggaaga
3241 gccttccacc caggggcagc cccaggccaa aggggacctg gaagggaggt gggccgtggc
3301 ccttgagtcc ccattgaggc ttggttcctt cccaatccag tggacttcgc agtccacttc
3361 tgacagcctc agtgaccctg gctccttgtg ccagagaacc cagcccaccc acggcagcag
3421 cccccagctc ccacctcccc ttgggcccac accttcttcc ctctctggag aaagggccct
3481 gggcctgcct caccacggac caaagggagt ctgccagggc ccctctccca gggaagcagc
3541 agcctcgccc ctggcagaga tgcctccctg agctagaacc ctctgttcct tccctgtgcc
3601 tcctccctcc ctctccgact cacaccacta gcctcagggg tctgagctcc agctcctttg
3661 ggcttcagct gccagtgtcc tgagccccag ggagaggggg ctggtgggtg cctaggcctg
3721 ggcagtggat ggccgtgaat gggtgcccac agtgtcaggc actgggcatg aggggttcct
3781 cccctccagc tccctgtgcc cccagggtcc tgggaggaga gacactggtg gggataggcc
3841 agccgcgcat cagactgtga accccacgaa ggagcccatt gtggcctaag aggctgccct
3901 cctgtgctca gccctgagga cagatgcctc cttcctcttt tccttccaaa agcaagcaag
3961 aggccgtggc tgctgtggga aatggtactg tacagctggc tctacttccc catggccctg
4021 agcgagtgga gtctgccacc caggatcccc aaggcacttg agggggaagg attctgctgg
4081 cctctgcgag tggtttcttg tgcactggca ccaagtgcgg gtccggcagc ttctgccccc
4141 tgcagaaccg gagagccagc taaggggtgg ggctgcgggg gttccgtgtc cacccccata
4201 catttatttc tgtaaataat gtgcactgaa taaattgtac agccggcaaa aaaaaaaaaa
4261 aaa
//