LOCUS BC034554 1584 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 3, mRNA (cDNA clone MGC:18107
IMAGE:4152390), complete cds.
ACCESSION BC034554
VERSION BC034554.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1584)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1584)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-JUL-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 19 Row: a Column: 24.
FEATURES Location/Qualifiers
source 1..1584
/db_xref="H-InvDB:HIT000051183"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:18107 IMAGE:4152390"
/tissue_type="Brain, glioblastoma with EGFR amplification"
/clone_lib="NCI_CGAP_Brn64"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1584
/gene="SERPINA3"
/gene_synonym="ACT"
/gene_synonym="GIG24"
/gene_synonym="GIG25"
/db_xref="GeneID:12"
/db_xref="HGNC:HGNC:16"
/db_xref="MIM:107280"
CDS 44..1315
/gene="SERPINA3"
/gene_synonym="ACT"
/gene_synonym="GIG24"
/gene_synonym="GIG25"
/codon_start=1
/product="serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 3"
/protein_id="AAH34554.1"
/db_xref="GeneID:12"
/db_xref="HGNC:HGNC:16"
/db_xref="MIM:107280"
/translation="MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTH
VDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKG
LKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRL
YGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWE
MPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELRYTGNASALF
ILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIE
EAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTI
VRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA"
BASE COUNT 412 a 428 c 400 g 344 t
ORIGIN
1 ggaatccacc agctacatcc agctccctga ggcagagttg agaatggaga gaatgttacc
61 tctcctggct ctggggctct tggcggctgg gttctgccct gctgtcctct gccaccctaa
121 cagcccactt gacgaggaga atctgaccca ggagaaccaa gaccgaggga cacacgtgga
181 cctcggatta gcctccgcca acgtggactt cgctttcagc ctgtacaagc agttagtcct
241 gaaggcccct gataagaatg tcatcttctc cccactgagc atctccaccg ccttggcctt
301 cctgtctctg ggggcccata ataccaccct gacagagatt ctcaaaggcc tcaagttcaa
361 cctcacggag acttctgagg cagaaattca ccagagcttc cagcacctcc tgcgcaccct
421 caatcagtcc agcgatgagc tgcagctgag tatgggaaat gccatgtttg tcaaagagca
481 actcagtctg ctggacaggt tcacggagga tgccaagagg ctgtatggct ccgaggcctt
541 tgccactgac tttcaggact cagctgcagc taagaagctc atcaacgact acgtgaagaa
601 tggaactagg gggaaaatca cagatctgat caaggacctt gactcgcaga caatgatggt
661 cctggtgaat tacatcttct ttaaagccaa atgggagatg ccctttgacc cccaagatac
721 tcatcagtca aggttctact tgagcaagaa aaagtgggta atggtgccca tgatgagttt
781 gcatcacctg actatacctt acttccggga cgaggagctg tcctgcaccg tggtggagct
841 gaggtacaca ggcaatgcca gcgcactctt catcctccct gatcaagaca agatggagga
901 agtggaagcc atgctgctcc cagagaccct gaagcggtgg agagactctc tggagttcag
961 agagataggt gagctctacc tgccaaagtt ttccatctcg agggactata acctgaacga
1021 catacttctc cagctgggca ttgaggaagc cttcaccagc aaggctgacc tgtcagggat
1081 cacaggggcc aggaacctag cagtctccca ggtggtccat aaggctgtgc ttgatgtatt
1141 tgaggagggc acagaagcat ctgctgccac agcagtcaaa atcaccctcc tttctgcatt
1201 agtggagaca aggaccattg tgcgtttcaa caggcccttc ctgatgatca ttgtccctac
1261 agacacccag aacatcttct tcatgagcaa agtcaccaat cccaagcaag cctagagctt
1321 gccatcaagc agtggggctc tcagtaagga acttggaatg caagctggat gcctgggtct
1381 ctgggcacag cctggcccct gtgcaccgag tggccatggc atgtgtggcc ctgtctgctt
1441 atccttggaa ggtgacagcg attccctgtg tagctctcac atgcacaggg gcccatggac
1501 tcttcagtct ggagggtcct gggcctcctg acagcaataa ataatttcgt tggaaaaaaa
1561 aaaaaaaaaa aaaaaaaaaa aaaa
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