LOCUS BC030607 3506 bp mRNA linear HUM 17-JUL-2006
DEFINITION Homo sapiens leucine rich repeat containing 8 family, member B,
mRNA (cDNA clone MGC:26970 IMAGE:4824652), complete cds.
ACCESSION BC030607
VERSION BC030607.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3506)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3506)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-MAY-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC030607.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
cDNA Library Preparation: Michael J. Brownstein (NHGRI) & Shiraki
Toshiyuki and Piero Carninci (RIKEN)
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 33 Row: j Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21245133.
FEATURES Location/Qualifiers
source 1..3506
/db_xref="H-InvDB:HIT000050996"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:26970 IMAGE:4824652"
/tissue_type="Testis"
/clone_lib="NIH_MGC_97"
/lab_host="DH10B"
/note="Vector: pBluescriptR"
gene 1..3506
/gene="LRRC8B"
/gene_synonym="KIAA0231"
/gene_synonym="TA-LRRP"
/db_xref="GeneID:23507"
/db_xref="HGNC:HGNC:30692"
CDS 744..3155
/gene="LRRC8B"
/gene_synonym="KIAA0231"
/gene_synonym="TA-LRRP"
/codon_start=1
/product="leucine rich repeat containing 8 family, member
B"
/protein_id="AAH30607.1"
/db_xref="GeneID:23507"
/db_xref="HGNC:HGNC:30692"
/translation="MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGA
LQLTQSRVLCCLPCKVEFDNHCAVPWDILKASMNTSSNPGTPLPLPLRIQNDLHRQQY
SYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCF
DSPWTTRALSETVAEQSVRPLKLSKSKILLSSSGCSADIDSGKQSLPYPQPGLESAGI
ESPTSSVLDKKEGEQAKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYV
PYFLTHITLEIDCSVDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSL
WWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVS
ENKLKQINLNNEWTVEKLKSKLVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELI
PEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFH
LKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKL
SLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVE
EIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLH
YLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNL
SPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLNTLPLPVTERLQT
CLDKC"
BASE COUNT 957 a 821 c 786 g 942 t
ORIGIN
1 gctgggcccg cagcctccgg cagccgggaa agtgcgggcg cggggccgca gcctgcccgc
61 ccggagcggc ccaggagcac gccgcgggga gcgcgggcgt ccggggctgg agtcgcgcag
121 ggctccagtt tgtgttttca gctgcctact agacctcact acctggatgg cccacagctc
181 tggagactgg aaggtccaag atcaagatac tacagatttg atttctggac gttgaacatg
241 gtgtaggagt agaaaagcaa cagggacgga aggagagaac ttaccccttc aagccctttt
301 ataaggcact aaatcccatc attgagggca gagtcctcat agcctaatca cctcctaaat
361 gctccatttc ttaatattgt tgcactgagg attaagcttc aacatgaatt ctgaagagga
421 cacaaacatc caaaccatag cagtcaatgc cttagccctt gatgttgcta tcaacctgag
481 attcggggat caaggaagga caggtaatag ttaacctctt ctgtgagaag tcagaaggtg
541 atctctttaa tgctttcttt ttaagaattt ttcaaattga gactaattgc agaggttcca
601 gttgaccagc attcatagga atgaagacaa acacagagat ggtgtgtcta agaaacttca
661 aaaggtgtag acctcctgac tgaagcatat tggatttatt taattttttt cactgtattt
721 ctgtcctcct acaagggaaa gtcatgatta cactaactga gctaaaatgc ttagcagatg
781 ctcagtcatc ttatcacatc ttaaaaccat ggtgggacgt cttctggtat tacatcacac
841 tgatcatgct gctggtggcc gtgctggccg gagctctcca gctgacgcag agcagggttc
901 tgtgctgtct tccatgcaaa gtggaatttg acaatcactg tgccgtgcct tgggacatcc
961 tgaaagccag catgaacaca tcctctaatc ctgggacacc gcttccgctc cccctccgaa
1021 ttcagaatga cctccaccga cagcagtact cctatattga tgccgtctgt tacgagaaac
1081 agctccattg gtttgcaaag tttttcccct atctggtgct cttgcacacg ctcatctttg
1141 cagcctgcag caacttttgg cttcactacc ccagtaccag ttccaggctc gagcattttg
1201 tggccatcct tcacaagtgc ttcgattctc catggaccac ccgcgccctt tcagaaacag
1261 tggctgagca gtcagtgagg cctctgaaac tctccaagtc caagattttg ctttcgtcct
1321 cagggtgttc agctgacata gattccggca aacagtcatt gccctaccca cagccaggtt
1381 tggagtcagc tggcatagaa agcccaactt ccagtgtcct ggacaagaag gagggtgaac
1441 aggccaaagc catctttgaa aaagtgaaaa gattccgcat gcatgtggag cagaaggaca
1501 tcatttatag agtatatctg aaacagataa tagtcaaagt cattttgttt gtgctcatca
1561 taacttatgt tccatatttt ttaacccaca tcactcttga aatcgactgt tcagttgatg
1621 tgcaggcttt tacaggatat aagcgctacc agtgtgtcta ttccttggca gaaatcttta
1681 aggtcctggc ttcattttat gtcattttgg ttatacttta tggtctgacc tcttcctaca
1741 gcctgtggtg gatgctgagg agttccctga agcaatattc ctttgaggcg ttaagagaaa
1801 aaagcaacta cagtgacatc cctgatgtca agaatgactt tgccttcatc cttcatctgg
1861 ctgatcagta tgatcctctt tattccaaac gcttctccat attcctatca gaggtcagtg
1921 agaacaaact gaaacagatc aacctcaata atgaatggac agttgagaaa ctgaaaagta
1981 agcttgtgaa aaatgcccag gacaagatag aactgcatct ttttatgctc aacggtcttc
2041 cagacaatgt ctttgagtta actgaaatgg aagtgctaag cctggagctt atcccagagg
2101 tgaagctgcc ctctgcagtc tcacagctgg tcaacctcaa ggagcttcgt gtgtaccatt
2161 catctctggt cgtagaccat cctgcactgg cctttctaga ggagaattta aaaatcctcc
2221 gcctgaaatt tactgaaatg ggaaaaatcc cacgctgggt atttcacctc aagaatctca
2281 aggaacttta tctttcgggc tgtgttctcc ctgaacagtt gagtactatg cagttggagg
2341 gctttcagga cttaaaaaat ctaaggaccc tgtacttgaa gagcagcctc tcccggatcc
2401 cacaagttgt tacagacctc ctgccttcat tgcagaaact gtcccttgat aatgagggaa
2461 gcaaactggt tgtgttgaac aacttgaaaa agatggtcaa tctgaaaagc ctagaactga
2521 tcagctgtga cctggaacgc atcccacatt ccattttcag cctgaataat ttgcatgagt
2581 tagacctaag ggaaaataac cttaaaactg tggaagagat cattagcttt cagcatcttc
2641 agaatctttc ctgcttaaag ttgtggcaca ataacattgc ttatattcct gcacagattg
2701 gggcattatc taacctagag cagctctctt tggaccataa taatattgag aatctgccct
2761 tgcagctttt cctatgcact aaactacatt atttggatct aagctataac cacttgacct
2821 tcattccaga agaaatccag tatctgagta atttgcagta ctttgctgtg accaacaaca
2881 atattgagat gctaccagat gggctgtttc agtgcaaaaa gctgcagtgt ttacttttgg
2941 ggaaaaatag cttgatgaat ttgtcccctc atgtgggtga gctgtcaaac cttactcatc
3001 tggagctcat tggtaattac ctggaaacac ttcctcctga actagaagga tgtcagtccc
3061 taaaacggaa ctgtctgatt gttgaggaga acttgctcaa tactcttcct ctccctgtaa
3121 cagaacgttt acagacgtgc ttagacaaat gttgacttaa agaaaagaga cccgtgtttc
3181 aaaatcattt ttaaaagtat gctcggccgg gcgtggtggc tcatgcctat aatcccagca
3241 ctttgggagg ccaagatggg cggattgctt gaggtcagga gttcgagacc agtctggcca
3301 acctggtgaa accccatctc tgctaaaact acaaaaaaat tagccaggcg tggtggcgtg
3361 cgcctgtaat cccagctact tgggaggctg acgcagggga attgcttgaa ccagggaggt
3421 ggaggttgca gtgagccgag attgtgccac tgtacaccag cctgggtgac agagcaagac
3481 tcttatctcg aaaaaaaaaa aaaaaa
//