LOCUS BC028067 3160 bp mRNA linear HUM 30-SEP-2003
DEFINITION Homo sapiens selectin P (granule membrane protein 140kDa, antigen
CD62), mRNA (cDNA clone IMAGE:5212431), partial cds.
ACCESSION BC028067
VERSION BC028067.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3160)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3160)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC028067.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Life Technologies, Inc.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 62 Row: g Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6031196.
FEATURES Location/Qualifiers
source 1..3160
/db_xref="H-InvDB:HIT000040420"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5212431"
/tissue_type="Blood, adult leukocytes"
/clone_lib="NIH_MGC_118"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene <1..3160
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/db_xref="GeneID:6403"
/db_xref="MIM:173610"
CDS <1..2370
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/codon_start=1
/product="SELP protein"
/protein_id="AAH28067.2"
/db_xref="GeneID:6403"
/db_xref="MIM:173610"
/translation="ANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYH
YSTKAYSWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTW
VGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTA
SCQDMSCSKQGECLETIGNYTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGN
FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLH
SAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPNEGTM
DCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPV
HGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDL
PVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIP
CTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMC
EAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCNNGFKLEGPNNVECTTSGRWSAT
PPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDST
LSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLN
GSAQTACQENGHWSTTVPTCQDDGKCPLNPHSHLGTYGVFTNAAFDPSP"
misc_feature 142..477
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/note="lectin_c; Region: Lectin C-type domain. This family
includes both long and short form C-type"
/db_xref="CDD:pfam00059"
misc_feature 595..768
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/note="CCP; Region: Domain abundant in complement control
proteins"
/db_xref="CDD:smart00032"
misc_feature 781..954
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/note="CCP; Region: Domain abundant in complement control
proteins"
/db_xref="CDD:smart00032"
misc_feature 967..1140
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/note="CCP; Region: Domain abundant in complement control
proteins"
/db_xref="CDD:smart00032"
misc_feature 1153..1326
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/note="CCP; Region: Domain abundant in complement control
proteins"
/db_xref="CDD:smart00032"
misc_feature 1339..1512
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/note="sushi; Region: Sushi domain (SCR repeat)"
/db_xref="CDD:pfam00084"
misc_feature 1525..1698
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/note="CCP; Region: Domain abundant in complement control
proteins"
/db_xref="CDD:smart00032"
misc_feature 1711..1884
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/note="CCP; Region: Domain abundant in complement control
proteins"
/db_xref="CDD:smart00032"
misc_feature 1921..2094
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/note="CCP; Region: Domain abundant in complement control
proteins"
/db_xref="CDD:smart00032"
misc_feature 2107..2280
/gene="SELP"
/gene_synonym="CD62"
/gene_synonym="CD62P"
/gene_synonym="GMP140"
/gene_synonym="GRMP"
/gene_synonym="PADGEM"
/gene_synonym="PSEL"
/note="CCP; Region: Domain abundant in complement control
proteins"
/db_xref="CDD:smart00032"
BASE COUNT 886 a 811 c 709 g 754 t
ORIGIN
1 gccaactgcc aaatagccat cttgtaccag agattccaga gagtggtctt tggaatttcc
61 caactccttt gcttcagtgc cctgatctct gaactaacaa accagaaaga agtggcagca
121 tggacttatc attacagcac aaaagcatac tcatggaata tttcccgtaa atactgccag
181 aatcgctaca cagacttagt ggccatccag aataaaaatg aaattgatta cctcaataag
241 gtcctaccct actacagctc ctactactgg attgggatcc gaaagaacaa taagacatgg
301 acatgggtgg gaaccaaaaa ggctctcacc aacgaggctg agaactgggc tgataatgaa
361 cctaacaaca aaaggaacaa cgaggactgc gtggagatat acatcaagag tccgtcagcc
421 cctggcaagt ggaatgatga gcactgcttg aagaaaaagc acgcattgtg ttacacagcc
481 tcctgccagg acatgtcctg cagcaaacaa ggagagtgcc tcgagaccat cgggaactac
541 acctgctcct gttaccctgg attctatggg ccagaatgtg aatacgtgag agagtgtgga
601 gaacttgagc tccctcaaca cgtgctcatg aactgcagcc accctctggg aaacttctct
661 tttaactcgc agtgcagctt ccactgcact gacgggtacc aagtaaatgg gcccagcaag
721 ctggaatgct tggcttctgg aatctggaca aataagcctc cacagtgttt agctgcccag
781 tgcccacccc tgaagattcc tgaacgagga aacatgacct gccttcattc tgcaaaagca
841 ttccagcatc agtctagctg cagcttcagt tgtgaagagg gatttgcatt agttggaccg
901 gaagtggtgc aatgcacagc ctcgggggta tggacagccc cagccccagt gtgtaaagct
961 gtgcagtgtc agcacctgga agcccccaat gaaggaacca tggactgtgt tcatccgctc
1021 actgcttttg cctatggctc cagctgtaaa tttgagtgcc agcccggcta cagagtgagg
1081 ggcttggaca tgctccgctg cattgactct ggacactggt ctgcaccctt gccaacctgt
1141 gaggctattt cgtgtgagcc gctggagagt cctgtccacg gaagcatgga ttgctctcca
1201 tccttgagag cgtttcagta tgacaccaac tgtagcttcc gctgtgctga aggtttcatg
1261 ctgagaggag ccgatatagt tcggtgtgat aacttgggac agtggacagc accagcccca
1321 gtctgtcaag ctttgcagtg ccaggatctc ccagttccaa atgaggcccg ggtgaactgc
1381 tcccacccct tcggtgcctt taggtaccag tcagtctgca gcttcacctg caatgaaggc
1441 ttgctcctgg tgggagcaag tgtgctacag tgcttggcta ctggaaactg gaattctgtt
1501 cctccagaat gccaagccat tccctgcaca cctttgctaa gccctcagaa tggaacaatg
1561 acctgtgttc aacctcttgg aagttccagt tataaatcca catgtcaatt catctgtgac
1621 gagggatatt ctttgtctgg accagaaaga ttggattgta ctcgatcggg acgctggaca
1681 gactccccac caatgtgtga agccatcaag tgcccagaac tctttgcccc agagcagggc
1741 agcctggatt gttctgacac tcgtggagaa ttcaatgttg gctccacctg ccatttctct
1801 tgtaacaacg gctttaagct ggaggggccc aataatgtgg aatgcacaac ttctggaaga
1861 tggtcagcta ctccaccaac ctgcaaaggc atagcatcac ttcctactcc aggggtgcaa
1921 tgtccagccc tcaccactcc tgggcaggga accatgtact gtaggcatca tccgggaacc
1981 tttggtttta ataccacttg ttactttggc tgcaacgctg gattcacact cataggagac
2041 agcactctca gctgcagacc ttcaggacaa tggacagcag taactccagc atgcagagct
2101 gtgaaatgct cagaactaca tgttaataag ccaatagcga tgaactgctc caacctctgg
2161 ggaaacttca gttatggatc aatctgctct ttccattgtc tagagggcca gttacttaat
2221 ggctctgcac aaacagcatg ccaagagaat ggccactggt caactaccgt gccaacctgc
2281 caagatgatg ggaaatgccc cttgaatcct cacagccacc taggaacata tggagttttt
2341 acaaacgctg catttgaccc gagtccttaa gagacctgtc cttttcctgg tctcctcatt
2401 cagcctccat atgatcctgt tgtgaacatc aagtttcctg ctacactgga cttaactata
2461 atgcatttgc tgcaggtttc cataaacacc catgaatcaa agacatggaa ttaccttaga
2521 ttagctctgg accagcctgt tggacccgct ctggaccaac cctgtttcct gagtttggga
2581 ttgtggtaca atctcaaatt ctcaacctac caccccttcc tgtcccacct cttctcttcc
2641 tgtaacacaa gccacagaag ccaggagcaa atgtttctgc agtagtctct gtgctttgac
2701 tcacctgtta cttgaaatac cagtgaacca aagagactgg agcatctgac tcacaagaag
2761 accagactgt ggagaaataa aaatacctct ttattttttg attgaaggaa ggttttctcc
2821 actttgttgg aaagcaggtg gcatctctaa ttggaagaaa ttcctgtagc atcttctgga
2881 gtctccagtg gttgctgttg atgaggcctc ttggacctct gctctgaggc ttccagagag
2941 tcctctggat ggcaccagag gctgcagaag gccaagaatc aagctagaag gccacatgtc
3001 accgtggacc ttcctgccac cagtcactgt ccctcaaatg acccaaagac caatattcaa
3061 atgcgtaatt aaaagaattt tccccaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3121 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//