LOCUS       BC021180                 726 bp    mRNA    linear   HUM 17-JUL-2006
DEFINITION  Homo sapiens high-mobility group box 4, mRNA (cDNA clone MGC:33358
            IMAGE:5266418), complete cds.
ACCESSION   BC021180
VERSION     BC021180.2
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 726)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 726)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JAN-2002) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     On Aug 25, 2003 this sequence version replaced BC021180.1.
            Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Miklos Palkovits, M.D., Ph.D.
            cDNA Library Preparation: Michael J. Brownstein (NHGRI) &  Shiraki
            Toshiyuki and Piero Carninci (RIKEN)
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Institute for Systems Biology
            http://www.systemsbiology.org
            contact: amadan@systemsbiology.org
            Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
            Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 47 Row: j Column: 1
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 57232747.
FEATURES             Location/Qualifiers
     source          1..726
                     /db_xref="H-InvDB:HIT000039122"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:33358 IMAGE:5266418"
                     /tissue_type="Testis"
                     /clone_lib="NIH_MGC_97"
                     /lab_host="DH10B"
                     /note="Vector: pBluescriptR"
     gene            1..726
                     /gene="HMGB4"
                     /gene_synonym="dJ1007G16.5"
                     /gene_synonym="FLJ40388"
                     /db_xref="GeneID:127540"
                     /db_xref="HGNC:HGNC:24954"
     CDS             114..674
                     /gene="HMGB4"
                     /gene_synonym="dJ1007G16.5"
                     /gene_synonym="FLJ40388"
                     /codon_start=1
                     /product="high-mobility group box 4"
                     /protein_id="AAH21180.1"
                     /db_xref="GeneID:127540"
                     /db_xref="HGNC:HGNC:24954"
                     /translation="MGKEIQLKPKANVSSYVHFLLNYRNKFKEQQPSTYVGFKEFSRK
                     CSEKWRSISKHEKAKYEALAKLDKARYQEEMMNYVGKRKKRRKRDPQAPRRPPSSFLL
                     FCQDHYAQLKRENPNWSVVQVAKATGKMWSTATDLEKHPYEQRVALLRAKYFEELELY
                     RKQCNARKKYRMSARNRCRGKRVRQS"
BASE COUNT          253 a          160 c          174 g          139 t
ORIGIN      
        1 agtcggaaaa attcgctgca agtacagcac tttctagatt gctcctggag tgtgggaaca
       61 acagtctctc ctgtccacgt tactgaatcc agaaaaaagg tgaacttacg aacatgggaa
      121 aagaaatcca gctaaagcct aaggcaaatg tctcttctta cgttcacttt ttgctgaatt
      181 acagaaacaa attcaaggag cagcagccaa gtacctacgt tggctttaaa gagttctcta
      241 gaaagtgttc ggaaaaatgg agatccatct caaagcatga aaaggccaaa tatgaagccc
      301 tggccaaact cgacaaagcc cgataccagg aagaaatgat gaattatgtt ggcaagagga
      361 agaaacggag aaagcgggat ccccaggcac ccagacggcc tccatcatcc ttcctactct
      421 tctgccaaga ccactatgct cagctgaaga gggagaaccc gaactggtcg gtggtgcagg
      481 tggccaaggc cacagggaag atgtggtcaa cagcgacaga cctggagaag cacccttatg
      541 agcaaagagt ggctctcctg agagctaagt acttcgagga acttgaactc taccgtaaac
      601 aatgtaatgc caggaagaag taccgaatgt cagctagaaa ccggtgcaga gggaaaagag
      661 tcaggcagag ctgatggatc cagtttgaaa aaacaaaatg ccattcaacc aaaaaaaaaa
      721 aaaaaa
//