LOCUS       BC020612                 433 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens hepcidin antimicrobial peptide, mRNA (cDNA clone
            MGC:22220 IMAGE:4715540), complete cds.
ACCESSION   BC020612
VERSION     BC020612.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 433)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2002) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: CLONTECH
            cDNA Library Preparation: CLONTECH Laboratories, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:       http://www-shgc.stanford.edu
            Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 37 Row: d Column: 14
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 50541944.
FEATURES             Location/Qualifiers
     source          1..433
                     /db_xref="H-InvDB:HIT000038848"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:22220 IMAGE:4715540"
                     /tissue_type="Liver"
                     /clone_lib="NIH_MGC_76"
                     /lab_host="DH10B"
                     /note="Vector: pDNR-LIB"
     gene            1..433
                     /gene="HAMP"
                     /gene_synonym="HEPC"
                     /gene_synonym="HFE2B"
                     /gene_synonym="LEAP-1"
                     /gene_synonym="LEAP1"
                     /db_xref="GeneID:57817"
                     /db_xref="HGNC:HGNC:15598"
                     /db_xref="MIM:606464"
     CDS             51..305
                     /gene="HAMP"
                     /gene_synonym="HEPC"
                     /gene_synonym="HFE2B"
                     /gene_synonym="LEAP-1"
                     /gene_synonym="LEAP1"
                     /codon_start=1
                     /product="hepcidin antimicrobial peptide"
                     /protein_id="AAH20612.1"
                     /db_xref="GeneID:57817"
                     /db_xref="HGNC:HGNC:15598"
                     /db_xref="MIM:606464"
                     /translation="MALSSQIWAACLLLLLLLASLTSGSVFPQQTGQLAELQPQDRAG
                     ARASWMPMFQRRRRRDTHFPICIFCCGCCHRSKCGMCCKT"
BASE COUNT          113 a          133 c          100 g           87 t
ORIGIN      
        1 accagagcaa gctcaagacc cagcagtggg acagccagac agacggcacg atggcactga
       61 gctcccagat ctgggccgct tgcctcctgc tcctcctcct cctcgccagc ctgaccagtg
      121 gctctgtttt cccacaacag acgggacaac ttgcagagct gcaaccccag gacagagctg
      181 gagccagggc cagctggatg cccatgttcc agaggcgaag gaggcgagac acccacttcc
      241 ccatctgcat tttctgctgc ggctgctgtc atcgatcaaa gtgtgggatg tgctgcaaga
      301 cgtagaacct acctgccctg cccccgtccc ctcccttcct tatttattcc tgctgcccca
      361 gaacataggt cttggaataa aatggctggt tcttttgttt tccaaaaaaa aaaaaaaaaa
      421 aaaaaaaaaa aaa
//