LOCUS       BC005324                 846 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens ribonuclease, RNase A family, 1 (pancreatic), mRNA
            (cDNA clone MGC:12408 IMAGE:3950230), complete cds.
ACCESSION   BC005324
VERSION     BC005324.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 846)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 846)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAR-2001) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: CLONTECH
            cDNA Library Preparation: CLONTECH Laboratories, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:       http://www-shgc.stanford.edu
            Contact:  (Dickson, Mark) mcd@paxil.stanford.edu
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 16 Row: g Column: 10
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 38201687.
FEATURES             Location/Qualifiers
     source          1..846
                     /db_xref="H-InvDB:HIT000032378"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:12408 IMAGE:3950230"
                     /tissue_type="Pancreas"
                     /clone_lib="NIH_MGC_78"
                     /lab_host="DH10B"
                     /note="Vector: pDNR-LIB"
     gene            1..846
                     /gene="RNASE1"
                     /gene_synonym="MGC12408"
                     /gene_synonym="RIB1"
                     /db_xref="GeneID:6035"
                     /db_xref="HGNC:HGNC:10044"
                     /db_xref="MIM:180440"
     CDS             107..577
                     /gene="RNASE1"
                     /gene_synonym="MGC12408"
                     /gene_synonym="RIB1"
                     /codon_start=1
                     /product="ribonuclease, RNase A family, 1 (pancreatic)"
                     /protein_id="AAH05324.1"
                     /db_xref="GeneID:6035"
                     /db_xref="HGNC:HGNC:10044"
                     /db_xref="MIM:180440"
                     /translation="MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSD
                     SSPSSSSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYK
                     SNSSMHITDCRLTNGSRYPNCAYRTSPKERHIIVACEGSPYVPVHFDASVEDST"
BASE COUNT          223 a          245 c          199 g          179 t
ORIGIN      
        1 gtataaggtc cacaccccgg gagctgagtg attgcagaaa ctggccttcc atctctctca
       61 gacaccaagc tgcagatcca ggcttttctg ggaaagtgag gccaccatgg ctctggagaa
      121 gtctcttgtc cggctccttc tgcttgtcct gatactgctg gtgctgggct gggtccagcc
      181 ttccctgggc aaggaatccc gggccaagaa attccagcgg cagcatatgg actcagacag
      241 ttcccccagc agcagctcca cctactgtaa ccaaatgatg aggcgccgga atatgacaca
      301 ggggcggtgc aaaccagtga acacctttgt gcacgagccc ctggtagatg tccagaatgt
      361 ctgtttccag gaaaaggtca cctgcaagaa cgggcagggc aactgctaca agagcaactc
      421 cagcatgcac atcacagact gccgcctgac aaacggctcc aggtacccca actgtgcata
      481 ccggaccagc ccgaaggaga gacacatcat tgtggcctgt gaagggagcc catatgtgcc
      541 agtccacttt gatgcttctg tggaggactc tacctaaggt cagagcagcg agatacccca
      601 cctccctcaa cctcatcctc tccacagctg cctcttccct cttccttccc tgctgtgaaa
      661 gaagtaacta cagttagggc tcctattcaa cacacacatg cttccctttc ctgagtccca
      721 tccctgcgtg attttggggg tgaagagtgg gttgtgaggt gggccccatg ttaacccctc
      781 cactctttct ttcaataaaa cgcagttgca aacaataaaa aaaaaaaaaa aaaaaaaaaa
      841 aaaaaa
//