LOCUS       BC004470                 759 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens PYD and CARD domain containing, mRNA (cDNA clone
            MGC:10332 IMAGE:3678925), complete cds.
ACCESSION   BC004470
VERSION     BC004470.2
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-MAR-2001) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     On Aug 20, 2003 this sequence version replaced BC004470.1.
            Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Louis M. Staudt, M.D., Ph.D.
            cDNA Library Preparation: Rubin Laboratory
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Institute for Systems Biology
            http://www.systemsbiology.org
            contact: amadan@systemsbiology.org
            Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
            Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAL Plate: 14 Row: g Column: 9
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 22035618.
FEATURES             Location/Qualifiers
     source          1..759
                     /db_xref="H-InvDB:HIT000031972"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:10332 IMAGE:3678925"
                     /tissue_type="Lymph, Burkitt lymphoma"
                     /clone_lib="NIH_MGC_8"
                     /lab_host="DH10B-R"
                     /note="Vector: pOTB7"
     gene            1..759
                     /gene="PYCARD"
                     /gene_synonym="ASC"
                     /gene_synonym="CARD5"
                     /gene_synonym="MGC10332"
                     /gene_synonym="TMS1"
                     /db_xref="GeneID:29108"
                     /db_xref="HGNC:HGNC:16608"
                     /db_xref="MIM:606838"
     CDS             237..644
                     /gene="PYCARD"
                     /gene_synonym="ASC"
                     /gene_synonym="CARD5"
                     /gene_synonym="MGC10332"
                     /gene_synonym="TMS1"
                     /codon_start=1
                     /product="PYD and CARD domain containing"
                     /protein_id="AAH04470.1"
                     /db_xref="GeneID:29108"
                     /db_xref="HGNC:HGNC:16608"
                     /db_xref="MIM:606838"
                     /translation="MGRARDAILDALENLTAEELKKFKLQAATHQGSGAAPAGIQAPP
                     QSAAKPGLHFIDQHRAALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKL
                     FSFTPAWNWTCKDLLLQALRESQSYLVEDLERS"
BASE COUNT          166 a          227 c          251 g          115 t
ORIGIN      
        1 gcgcgatcct ggcgtccccc gacggcctgg ggccccaatc cagaggcctg ggtgggaggg
       61 gaccaagggt gtagtaagga agcgcctttt gctggagggc aacggaccgg ggcggggagt
      121 cgggagacca gagtgggagg aaggcgggga gtccaggttc cgccccggag ccgacttcct
      181 cctggtcggc ggctgcagcg gggtgagcgg cggcagcggc cggggatcct ggagccatgg
      241 ggcgcgcgcg cgacgccatc ctggatgcgc tggagaacct gaccgccgag gagctcaaga
      301 agttcaagct gcaggcggcc acgcaccagg gctctggagc cgcgccagct gggatccagg
      361 cccctcctca gtcggcagcc aagccaggcc tgcactttat agaccagcac cgggctgcgc
      421 ttatcgcgag ggtcacaaac gttgagtggc tgctggatgc tctgtacggg aaggtcctga
      481 cggatgagca gtaccaggca gtgcgggccg agcccaccaa cccaagcaag atgcggaagc
      541 tcttcagttt cacaccagcc tggaactgga cctgcaagga cttgctcctc caggccctaa
      601 gggagtccca gtcctacctg gtggaggacc tggagcggag ctgaggctcc ttcccagcaa
      661 cactccggtc agcccctggc aatcccacca aatcatcctg aatctgatct ttttatacac
      721 aatatacgaa aagccagctt gaaaaaaaaa aaaaaaaaa
//