LOCUS       CAB93533.1               956 aa    PRT              HUM 07-OCT-2008
DEFINITION  Homo sapiens cyld protein.
ACCESSION   AJ250014-1
PROTEIN_ID  CAB93533.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5371)
  AUTHORS   Stratton M.R.
  JOURNAL   Submitted (29-NOV-1999) to the INSDC. Stratton M.R., Cancer
            Genetics, Institute of Cancer Research, 15 Cotswold Rd, Sutton,,
            Surrey. SM2 5NG., UNITED KINGDOM.
REFERENCE   2
  AUTHORS   Bignell G.R., Brown C., Biggs P.J., Lakhani S.R., Jones C.,
            Hansen J., Blair E., Hofmann B., Siebert R., Turner G., Evans D.G.,
            Schrander-Stumpel C., Beemer F.A., Van Den Ouweland A., Halley D.,
            Delpech B., Cleveland M.G., Leigh I., Leisti J., Rasmussen S.,
            Wallace M.R., Fenske C., Banerjee P., Oiso N., Chaggar R.,
            Merrett S., Leonard N., Huber M., Hohl D., Chapman P., Burn J.,
            Swift S., Smith A., Ashworth A., Stratton M.R.
  TITLE     Identification of the familial cylindromatosis tumour-suppressor
            gene
  JOURNAL   Nat Genet 25(2), 160-165(2000).
   PUBMED   10835629
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000245961"
                     /organism="Homo sapiens"
                     /chromosome="16"
                     /map="16q12 - q13"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     protein         /gene="cyld"
                     /function="tumour suppressor/recessive oncogene"
                     /note="Familial Cylindromatosis Gene"
                     /db_xref="GOA:Q9NQC7"
                     /db_xref="H-InvDB:HIT000245961.14"
                     /db_xref="HGNC:HGNC:2584"
                     /db_xref="InterPro:IPR000938"
                     /db_xref="InterPro:IPR001394"
                     /db_xref="InterPro:IPR018200"
                     /db_xref="InterPro:IPR028889"
                     /db_xref="InterPro:IPR036859"
                     /db_xref="InterPro:IPR038765"
                     /db_xref="PDB:1IXD"
                     /db_xref="PDB:1WHL"
                     /db_xref="PDB:1WHM"
                     /db_xref="PDB:2VHF"
                     /db_xref="UniProtKB/Swiss-Prot:Q9NQC7"
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSSGLWSQEK VTSPYWEERI FYLLLQECSV TDKQTQKLLK VPKGSIGQYI QDRSVGHSRI
       61 PSAKGKKNQI GLKILEQPHA VLFVDEKDVV EINEKFTELL LAITNCEERF SLFKNRNRLS
      121 KGLQIDVGCP VKVQLRSGEE KFPGVVRFRG PLLAERTVSG IFFGVELLEE GRGQGFTDGV
      181 YQGKQLFQCD EDCGVFVALD KLELIEDDDT ALESDYAGPG DTMQVELPPL EINSRVSLKV
      241 GETIESGTVI FCDVLPGKES LGYFVGVDMD NPIGNWDGRF DGVQLCSFAC VESTILLHIN
      301 DIIPALSESV TQERRPPKLA FMSRGVGDKG SSSHNKPKAT GSTSDPGNRN RSELFYTLNG
      361 SSVDSQPQSK SKNTWYIDEV AEDPAKSLTE ISTDFDRSSP PLQPPPVNSL TTENRFHSLP
      421 FSLTKMPNTN GSIGHSPLSL SAQSVMEELN TAPVQESPPL AMPPGNSHGL EVGSLAEVKE
      481 NPPFYGVIRW IGQPPGLNEV LAGLELEDEC AGCTDGTFRG TRYFTCALKK ALFVKLKSCR
      541 PDSRFASLQP VSNQIERCNS LAFGGYLSEV VEENTPPKME KEGLEIMIGK KKGIQGHYNS
      601 CYLDSTLFCL FAFSSVLDTV LLRPKEKNDV EYYSETQELL RTEIVNPLRI YGYVCATKIM
      661 KLRKILEKVE AASGFTSEEK DPEEFLNILF HHILRVEPLL KIRSAGQKVQ DCYFYQIFME
      721 KNEKVGVPTI QQLLEWSFIN SNLKFAEAPS CLIIQMPRFG KDFKLFKKIF PSLELNITDL
      781 LEDTPRQCRI CGGLAMYECR ECYDDPDISA GKIKQFCKTC NTQVHLHPKR LNHKYNPVSL
      841 PKDLPDWDWR HGCIPCQNME LFAVLCIETS HYVAFVKYGK DDSAWLFFDS MADRDGGQNG
      901 FNIPQVTPCP EVGEYLKMSL EDLHSLDSRR IQGCARRLLC DAYMCMYQSP TMSLYK
//