LOCUS       AAH67262.1               948 aa    PRT              HUM 30-MAR-2004
DEFINITION  Homo sapiens ARHGEF1 protein protein.
ACCESSION   BC067262-1
PROTEIN_ID  AAH67262.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2907)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 2907)
  AUTHORS   Strausberg,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-MAR-2004) National Institutes of Health, Mammalian
            Gene Collection (MGC), Cancer Genomics Office, National Cancer
            Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
            USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: ATCC
            cDNA Library Preparation: Life Technologies, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Genome Sequence Centre,
            BC Cancer Agency, Vancouver, BC, Canada
            info@bcgsc.bc.ca
            Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
            Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
            Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
            Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
            Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
            Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
            Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
            Schein, Asim Siddiqui, Rob Holt, Marco Marra.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 141 Row: i Column: 17
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 15011971.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000262507"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:74807 IMAGE:6502165"
                     /tissue_type="Uterus, leiomyosarcoma"
                     /clone_lib="NIH_MGC_71"
                     /lab_host="DH10B"
                     /note="Vector: pCMV-SPORT6"
     protein         /gene="ARHGEF1"
                     /gene_synonym="GEF1"
                     /gene_synonym="LBCL2"
                     /gene_synonym="P115-RHOGEF"
                     /gene_synonym="SUB1.5"
                     /db_xref="GeneID:9138"
                     /db_xref="MIM:601855"
BEGIN
        1 MASLSTWSSP AEPREMEDFA RGAASPGPSR PGLVPVSIIG AEDEDFENEL ETNSEEQNSQ
       61 FQSLEQVKRR PAHLMALLQH VALQFEPGPL VLRVPVPPNV AFELDRTRAD LISEDVQRRF
      121 VQEVVQSQQV AVGRQLEDFR SKRLMGMTPW EQELAQLEAW VGRDRASYEA RERHVAERLL
      181 MHLEEMQHTI STDEEKSAAV VNAIGLYMRH LGVRTKSGDK KSGRNFFRKK VMGNRRSDEP
      241 AKTKKGLSSI LDAARWNRGE PQVPDFRHLK AEVDAEKPGA TDRKGGVGMP SRDRNIGAPG
      301 QDTPGVSLHP LSLDSPDREP GADAPLELGD SSPQGPMSLE SLAPPESTDE GAETESPEPG
      361 DEGEPGRSGL ELEPEEPPGW RELVPPDTLH SLPKSQVKRQ EVISELLVTE AAHVRMLRVL
      421 HDLFFQPMAE CLFFPLEELQ NIFPSLDELI EVHSLFLDRL MKRRQESGYL IEEIGDVLLA
      481 RFDGAEGSWF QKISSRFCSR QSFALEQLKA KQRKDPRFCA FVQEAESRPR CRRLQLKDMI
      541 PTEMQRLTKY PLLLQSIGQN TEEPTEREKV ELAAECCREI LHHVNQAVRD MEDLLRLKDY
      601 QRRLDLSHLR QSSDPMLSEF KNLDITKKKL VHEGPLTWRV TKDKAVEVHV LLLDDLLLLL
      661 QRQDERLLLK SHSRTLTPTP DGKTMLRPVL RLTSAMTREV ATDHKAFYVL FTWDQEAQIY
      721 ELVAQTVSER KNWCALITET AGSLKVPAPA SRPKPRPSPS STREPLLSSS ENGNGGRETS
      781 PADARTERIL SDLLPFCRPG PEGQLAATAL RKGVGGGILP PETPPVSAWG ELCPPAWLHL
      841 RFPPRKAFCK KERNGGEDVR DHPHPHSCRS ISHPEGLRRG SCGPRLGGAQ LGLLAPHEPR
      901 PSLPPALCLG DSGLHSGGHH GDPGHLSIAC GGHPSTPTPK CLRSVFIP
//