LOCUS       AAH12860.1               474 aa    PRT              HUM 11-SEP-2007
DEFINITION  Homo sapiens RhoA/RAC/CDC42 exchange factor protein.
ACCESSION   BC012860-1
PROTEIN_ID  AAH12860.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2166)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 2166)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2001) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: David N. Louis, M.D.
            cDNA Library Preparation: Life Technologies, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Baylor College of Medicine Human Genome
            Sequencing Center
            Center code: BCM-HGSC
            Web site: http://www.hgsc.bcm.tmc.edu/cdna/
            Contact: amg@bcm.tmc.edu
            Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
            Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
            A.N., Gibbs, R.A.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 12 Row: j Column: 13
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 19311007.
FEATURES             Qualifiers
     source          /db_xref="H-InvDB:HIT000036003"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:18298 IMAGE:4179764"
                     /tissue_type="Brain, anaplastic oligodendroglioma with
                     1p/19q loss"
                     /clone_lib="NCI_CGAP_Brn67"
                     /lab_host="DH10B"
                     /note="Vector: pCMV-SPORT6"
     protein         /gene="GEFT"
                     /gene_synonym="p63RhoGEF"
                     /db_xref="GeneID:115557"
                     /db_xref="MIM:610215"
BEGIN
        1 MLEPALATGE ELPELTLLTT LLEGPGDKTQ PPEEETLSQA PESEEEQKKK ALERSMYVLS
       61 ELVETEKMYV DDLGQIVEGY MATMAAQGVP ESLRGRDRIV FGNIQQIYEW HRDYFLQELQ
      121 RCLKDPDWLA QLFIKHERRL HMYVVYCQNK PKSEHVVSEF GDSYFEELRQ QLGHRLQLND
      181 LLIKPVQRIM KYQLLLKDFL KYYNRAGMDT ADLEQAVEVM CFVPKRCNDM MTLGRLRGFE
      241 GKLTAQGKLL GQDTFWVTEP EAGGLLSSRG RERRVFLFEQ IIIFSEALGG GVRGGTQPGY
      301 VYKNSIKVSC LGLEGNLQGD PCRFALTSRG PEGGIQRYVL QAADPAISQA WIKHVAQILE
      361 SQRDFLNALQ SPIEYQRRES QTNSLGRPRG PGVGSPGRIR LGDQAQGSTH TPINGSLPSL
      421 LLSPKGEVAR ALLPLDKQAL GDIPQAPHDS PPVSPTPKTP PCQARLAKLD EDEL
//