LOCUS BC017802 905 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens small proline-rich protein 3, mRNA (cDNA clone
MGC:22360 IMAGE:4288753), complete cds.
ACCESSION BC017802
VERSION BC017802.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 905)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 905)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 36 Row: a Column: 10.
FEATURES Location/Qualifiers
source 1..905
/db_xref="H-InvDB:HIT000038141"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22360 IMAGE:4288753"
/tissue_type="Skeletal Muscle"
/clone_lib="NIH_MGC_81"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..905
/gene="SPRR3"
/db_xref="GeneID:6707"
/db_xref="MIM:182271"
CDS 65..550
/gene="SPRR3"
/codon_start=1
/product="SPRR3 protein"
/protein_id="AAH17802.1"
/db_xref="GeneID:6707"
/db_xref="MIM:182271"
/translation="MSSYQQKQTFTPPPQLQQQQVKQPSQPPPQEIFVPTTKEPCHSK
VPQPGNTKIPEPGCTKVPEPGCTKVPEPGCTKVPEPGCTKVPEPGCTKVPEPGYTKVP
EPGSIKVPDQGFIKFPEPGAIKVPEQGYTKVPVPGYTKVPEPCPSTVTPGPAQQKTKQ
K"
misc_feature 155..541
/gene="SPRR3"
/note="Cornifin; Region: Cornifin (SPRR) family. SPRR
genes (formerly SPR) encode a novel class of polypeptides
(small proline rich proteins) that are strongly induced
during differentiation of human epidermal keratinocytes in
vitro and in vivo.The most characteristic feature of the
SPRR gene family resides in the structure of the central
segments of the encoded polypeptides that are built up
from tandemly repeated units of either eight (SPRR1 and
SPRR3) or nine (SPRR2) amino acids with the general
consensus XKXPEPXX where X is any amino acid"
/db_xref="CDD:pfam02389"
BASE COUNT 270 a 259 c 176 g 200 t
ORIGIN
1 accagatccc agaggctgaa cagctcgact ttctctgcac agcaggtcca gcatcctttg
61 aaacatgagt tcttaccagc agaagcagac ctttacccca ccacctcagc ttcaacagca
121 gcaggtgaaa caacccagcc agcctccacc tcaggaaata tttgttccca caaccaagga
181 gccatgccac tcaaaggttc cacaacctgg aaacacaaag attccagagc caggctgtac
241 caaggtccct gagccaggct gtaccaaggt ccctgagcca ggttgtacca aggtccctga
301 gccaggatgt accaaggtcc ctgagccagg ttgtaccaag gtccctgagc caggctacac
361 caaggtccct gagccaggca gcatcaaggt ccctgaccaa ggcttcatca agtttcctga
421 gccaggtgcc atcaaagttc ctgagcaagg atacaccaaa gttcctgtgc caggctacac
481 aaaggtacca gagccatgtc cttcaacggt cactccaggc ccagctcagc agaagaccaa
541 gcagaagtaa tttggtgcac agacaagccc ttgagaagcc aaccaccaga tgctggacac
601 cctcttccca tctgtttctg tgtcttaatt gtctgtagac cttgtaatca gtacattctc
661 accccaagcc atagtctctc tcttatttgt atcctaaaaa tacgtactat aaagcttttg
721 ttcacacaca ctctgaagaa tcctgtaagc ccctgaatta agcagaaagt cttcatggct
781 tttctggtct tcggctgctc agggttcatc tgaagattcg aatgaaaaga aatgcatgtt
841 tcctgctctg ccctcattaa attgctttta attccaaaaa aaaaaaaaaa aaaaaaaaaa
901 aaaaa
//