LOCUS       BC017802                 905 bp    mRNA    linear   HUM 04-OCT-2003
DEFINITION  Homo sapiens small proline-rich protein 3, mRNA (cDNA clone
            MGC:22360 IMAGE:4288753), complete cds.
VERSION     BC017802.1
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 905)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 905)
  AUTHORS   Strausberg,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-DEC-2001) National Institutes of Health, Mammalian
            Gene Collection (MGC), Cancer Genomics Office, National Cancer
            Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
  REMARK    NIH-MGC Project URL:
COMMENT     Contact: MGC help desk
            Tissue Procurement: CLONTECH
            cDNA Library Preparation: CLONTECH Laboratories, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Sequencing Group at the Stanford Human Genome
            Center, Stanford University School of Medicine, Stanford, CA  94305
            Web site:
            Contact:  (Dickson, Mark)
            Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
            R. M.
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at:
            Series: IRAL Plate: 36 Row: a Column: 10.
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Homo sapiens"
                     /clone="MGC:22360 IMAGE:4288753"
                     /tissue_type="Skeletal Muscle"
                     /note="Vector: pDNR-LIB"
     gene            1..905
     CDS             65..550
                     /product="SPRR3 protein"
     misc_feature    155..541
                     /note="Cornifin; Region: Cornifin (SPRR) family. SPRR
                     genes (formerly SPR) encode a novel class of polypeptides
                     (small proline rich proteins) that are strongly induced
                     during differentiation of human epidermal keratinocytes in
                     vitro and in vivo.The most characteristic feature of the
                     SPRR gene family resides in the structure of the central
                     segments of the encoded polypeptides that are built up
                     from tandemly repeated units of either eight (SPRR1 and
                     SPRR3) or nine (SPRR2) amino acids with the general
                     consensus XKXPEPXX where X is any amino acid"
BASE COUNT          270 a          259 c          176 g          200 t
        1 accagatccc agaggctgaa cagctcgact ttctctgcac agcaggtcca gcatcctttg
       61 aaacatgagt tcttaccagc agaagcagac ctttacccca ccacctcagc ttcaacagca
      121 gcaggtgaaa caacccagcc agcctccacc tcaggaaata tttgttccca caaccaagga
      181 gccatgccac tcaaaggttc cacaacctgg aaacacaaag attccagagc caggctgtac
      241 caaggtccct gagccaggct gtaccaaggt ccctgagcca ggttgtacca aggtccctga
      301 gccaggatgt accaaggtcc ctgagccagg ttgtaccaag gtccctgagc caggctacac
      361 caaggtccct gagccaggca gcatcaaggt ccctgaccaa ggcttcatca agtttcctga
      421 gccaggtgcc atcaaagttc ctgagcaagg atacaccaaa gttcctgtgc caggctacac
      481 aaaggtacca gagccatgtc cttcaacggt cactccaggc ccagctcagc agaagaccaa
      541 gcagaagtaa tttggtgcac agacaagccc ttgagaagcc aaccaccaga tgctggacac
      601 cctcttccca tctgtttctg tgtcttaatt gtctgtagac cttgtaatca gtacattctc
      661 accccaagcc atagtctctc tcttatttgt atcctaaaaa tacgtactat aaagcttttg
      721 ttcacacaca ctctgaagaa tcctgtaagc ccctgaatta agcagaaagt cttcatggct
      781 tttctggtct tcggctgctc agggttcatc tgaagattcg aatgaaaaga aatgcatgtt
      841 tcctgctctg ccctcattaa attgctttta attccaaaaa aaaaaaaaaa aaaaaaaaaa
      901 aaaaa