LOCUS       Z70520                   836 bp    mRNA    linear   HUM 14-NOV-2006
DEFINITION  H.sapiens FAS/Apo 1 mRNA for FAS soluble protein (clone FAS
            Exo4,6Del).
ACCESSION   Z70520
VERSION     Z70520.1
KEYWORDS    FAS soluble protein; FAS/Apo 1 gene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   Papoff G., Cascino I., Eramo A., Starace G., Lynch D.H., Ruberti G.
  TITLE     An N-terminal domain shared by Fas/Apo-1 (CD95) soluble variants
            prevents cell death in vitro
  JOURNAL   J. Immunol. 156(12), 4622-4630(1996).
   PUBMED   8648105
REFERENCE   2  (bases 1 to 836)
  AUTHORS   Ruberti G.
  JOURNAL   Submitted (01-APR-1996) to the INSDC. Ruberti G., Cell Biology
            Institute, C.N.R., Immunology, viale C.Marx 43, Rome, Italy,
            I-00137
FEATURES             Location/Qualifiers
     source          1..836
                     /db_xref="H-InvDB:HIT000327887"
                     /organism="Homo sapiens"
                     /chromosome="10"
                     /isolate="LN"
                     /mol_type="mRNA"
                     /clone="FAS Exo4,6Del"
                     /cell_type="PHA-activated PBMC"
                     /db_xref="taxon:9606"
     CDS             1..399
                     /product="FAS soluble protein"
                     /note="Alternative splicing variant of FAS gene missing
                     exons 4 and 6. Exon 5 translated in a different frame up
                     to a new stop codon at the beginning of exon 7."
                     /db_xref="GOA:P25445"
                     /db_xref="H-InvDB:HIT000327887.13"
                     /db_xref="HGNC:HGNC:11920"
                     /db_xref="InterPro:IPR000488"
                     /db_xref="InterPro:IPR001368"
                     /db_xref="InterPro:IPR008063"
                     /db_xref="InterPro:IPR011029"
                     /db_xref="InterPro:IPR033998"
                     /db_xref="InterPro:IPR033999"
                     /db_xref="PDB:1BZI"
                     /db_xref="PDB:1DDF"
                     /db_xref="PDB:2NA7"
                     /db_xref="PDB:3EWT"
                     /db_xref="PDB:3EZQ"
                     /db_xref="PDB:3THM"
                     /db_xref="PDB:3TJE"
                     /db_xref="UniProtKB/Swiss-Prot:P25445"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /protein_id="CAA94431.1"
                     /translation="MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTV
                     ETQNLEGLHHDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCR
                     RCRLCDEGHDVNMESSRNAHSPATPSAKRK"
     exon            <1..30
                     /number=1
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            31..196
                     /number=2
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            197..334
                     /number=3
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            335..396
                     /number=5
                     /note="Translated in a different frame in this variant."
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            397..479
                     /number=7
                     /note="Not translated in this variant as there is a stop
                     codon at 397."
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            480..504
                     /number=8
                     /note="Not translated in this variant."
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            505..>836
                     /number=9
                     /note="Not translated in this variant."
                     /experiment="experimental evidence, no additional details
                     recorded"
BASE COUNT          297 a          166 c          183 g          190 t
ORIGIN      
        1 atgctgggca tctggaccct cctacctctg gttcttacgt ctgttgctag attatcgtcc
       61 aaaagtgtta atgcccaagt gactgacatc aactccaagg gattggaatt gaggaagact
      121 gttactacag ttgagactca gaacttggaa ggcctgcatc atgatggcca attctgccat
      181 aagccctgtc ctccaggtga aaggaaagct agggactgca cagtcaatgg ggatgaacca
      241 gactgcgtgc cctgccaaga agggaaggag tacacagaca aagcccattt ttcttccaaa
      301 tgcagaagat gtagattgtg tgatgaagga catgatgtga acatggaatc atcaaggaat
      361 gcacactcac cagcaacacc aagtgcaaag aggaagtgaa gagaaaggaa gtacagaaaa
      421 catgcagaaa gcacagaaag gaaaaccaag gttctcatga atctccaacc ttaaatcctg
      481 aaacagtggc aataaattta tctgatgttg acttgagtaa atatatcacc actattgctg
      541 gagtcatgac actaagtcaa gttaaaggct ttgttcgaaa gaatggtgtc aatgaagcca
      601 aaatagatga gatcaagaat gacaatgtcc aagacacagc agaacagaaa gttcaactgc
      661 ttcgtaattg gcatcaactt catggaaaga aagaagcgta tgacacattg attaaagatc
      721 tcaaaaaagc caatctttgt actcttgcag agaaaattca gactatcatc ctcaaggaca
      781 ttactagtga ctcagaaaat tcaaacttca gaaatgaaat ccaaagcttg gtctag
//