LOCUS       Z47995                   698 bp    mRNA    linear   HUM 14-NOV-2006
DEFINITION  H.sapiens FAS Del3 mRNA.
ACCESSION   Z47995
VERSION     Z47995.1
KEYWORDS    FAS gene.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   2  (bases 1 to 698)
  AUTHORS   Ruberti G.
  JOURNAL   Submitted (24-JAN-1995) to the INSDC. Ruberti G., Cell Biology
            Institute, C.N.R., Immunology, viale C.Marx 43, Rome, Italy,
            I-00137
REFERENCE   3  (bases 1 to 698)
  AUTHORS   Cascino I., Fiucci G., Papoff G., Ruberti G.
  TITLE     Three functional soluble forms of the human apoptosis-inducing Fas
            molecule are produced by alternative splicing
  JOURNAL   J. Immunol. 154(6), 2706-2713(1995).
   PUBMED   7533181
FEATURES             Location/Qualifiers
     source          1..698
                     /db_xref="H-InvDB:HIT000327396"
                     /organism="Homo sapiens"
                     /chromosome="10"
                     /isolate="GF"
                     /mol_type="mRNA"
                     /clone="FAS DEL3"
                     /cell_type="PHA-activated PBMC"
                     /db_xref="taxon:9606"
     CDS             1..261
                     /standard_name="FAS/Apo 1"
                     /product="FAS soluble protein"
                     /note="Alternative splicing variant of FAS gene missing
                     exons 3,4 and 6. Exon 5 translated in a different frame up
                     to a new stop codon at the beginning of exon 7."
                     /db_xref="GOA:P25445"
                     /db_xref="H-InvDB:HIT000327396.13"
                     /db_xref="HGNC:HGNC:11920"
                     /db_xref="InterPro:IPR000488"
                     /db_xref="InterPro:IPR001368"
                     /db_xref="InterPro:IPR008063"
                     /db_xref="InterPro:IPR011029"
                     /db_xref="InterPro:IPR033998"
                     /db_xref="InterPro:IPR033999"
                     /db_xref="PDB:1BZI"
                     /db_xref="PDB:1DDF"
                     /db_xref="PDB:2NA7"
                     /db_xref="PDB:3EWT"
                     /db_xref="PDB:3EZQ"
                     /db_xref="PDB:3THM"
                     /db_xref="PDB:3TJE"
                     /db_xref="UniProtKB/Swiss-Prot:P25445"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /protein_id="CAA88033.1"
                     /translation="MLGIWTLLPLVLTSVARLSSKSVNAQVTDINSKGLELRKTVTTV
                     ETQNLEGLHHDGQFCHKPCPPDVNMESSRNAHSPATPSAKRK"
     exon            <1..30
                     /standard_name="FAS/Apo 1"
                     /number=1
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            31..196
                     /standard_name="FAS/Apo 1"
                     /number=2
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            197..258
                     /standard_name="FAS/Apo 1"
                     /number=5
                     /note="Translated in a different frame in this variant."
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            259..341
                     /standard_name="FAS/Apo 1"
                     /number=7
                     /note="Not translated in this variant as there is a stop
                     codon at 259."
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            342..366
                     /standard_name="FAS/Apo 1"
                     /number=8
                     /note="Not translated in this variant."
                     /experiment="experimental evidence, no additional details
                     recorded"
     exon            367..>698
                     /standard_name="FAS/Apo 1"
                     /number=9
                     /note="Not translated in this variant."
                     /experiment="experimental evidence, no additional details
                     recorded"
BASE COUNT          251 a          141 c          142 g          164 t
ORIGIN      
        1 atgctgggca tctggaccct cctacctctg gttcttacgt ctgttgctag attatcgtcc
       61 aaaagtgtta atgcccaagt gactgacatc aactccaagg gattggaatt gaggaagact
      121 gttactacag ttgagactca gaacttggaa ggcctgcatc atgatggcca attctgccat
      181 aagccctgtc ctccagatgt gaacatggaa tcatcaagga atgcacactc accagcaaca
      241 ccaagtgcaa agaggaagtg aagagaaagg aagtacagaa aacatgcaga aagcacagaa
      301 aggaaaacca aggttctcat gaatctccaa ccttaaatcc tgaaacagtg gcaataaatt
      361 tatctgatgt tgacttgagt aaatatatca ccactattgc tggagtcatg acactaagtc
      421 aagttaaagg ctttgttcga aagaatggtg tcaatgaagc caaaatagat gagatcaaga
      481 atgacaatgt ccaagacaca gcagaacaga aagttcaact gcttcgtaat tggcatcaac
      541 ttcatggaaa gaaagaagcg tatgacacat tgattaaaga tctcaaaaaa gccaatcttt
      601 gtactcttgc agagaaaatt cagactatca tcctcaagga cattactagt gactcagaaa
      661 attcaaactt cagaaatgaa atccaaagct tggtctag
//