LOCUS X52520 2754 bp mRNA linear HUM 07-OCT-2008
DEFINITION Human mRNA for tyrosine aminotransferase (TAT) (EC 2.6.1.5).
ACCESSION X52520
VERSION X52520.1
KEYWORDS aminotransferase; transferase; tyrosine aminotransferase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1
AUTHORS Scherer G.
JOURNAL Submitted (08-MAR-1990) to the INSDC. Scherer G., Institute of
Human Genetics, Albertstr 11, D 7800 Freiburg.
REMARK 9bases 1-2754)
REFERENCE 2 (bases 1 to 2754)
AUTHORS Rettenmeier R., Natt E., Zentgraf H., Scherer G.
TITLE Isolation and characterization of the human tyrosine
aminotransferase gene
JOURNAL Nucleic Acids Res. 18(13), 3853-3861(1990).
PUBMED 1973834
COMMENT See <X52507>-<X52520>.
Data kindly reviewed (26-JUL-1990) by G. Scherer
FEATURES Location/Qualifiers
source 1..2754
/db_xref="H-InvDB:HIT000321783"
/organism="Homo sapiens"
/chromosome="16q22.1"
/mol_type="mRNA"
/clone_lib="genomic (phage) + cDNA"
/clone="lambda-hTAT1, phcTAT2-16 + phcTAT3a-6"
/tissue_type="placenta (genomic) and liver (cDNA)"
/db_xref="taxon:9606"
CDS 97..1461
/note="tyrosine aminotransferase (AA 1-454)"
/db_xref="GOA:P17735"
/db_xref="H-InvDB:HIT000321783.14"
/db_xref="HGNC:HGNC:11573"
/db_xref="InterPro:IPR004838"
/db_xref="InterPro:IPR004839"
/db_xref="InterPro:IPR005957"
/db_xref="InterPro:IPR005958"
/db_xref="InterPro:IPR011715"
/db_xref="InterPro:IPR015421"
/db_xref="InterPro:IPR015422"
/db_xref="InterPro:IPR015424"
/db_xref="PDB:3DYD"
/db_xref="UniProtKB/Swiss-Prot:P17735"
/protein_id="CAA36750.1"
/translation="MDPYMIQMSSKGNLPSILDVHVNVGGRSSVPGKMKGRKARWSVR
PSDMAKKTFNPIRAIVDNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALD
SGKYNGYAPSIGFLSSREEIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQ
NILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVNNPS
NPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCG
GLAKRWLVPGWRLGWILIHDRRDIFGNEIRDGLVKLSQRILGPCTIVQGALKSILCRT
PGEFYHNTLSFLKSNADLCYGALAAIPGLRPVRPSGAMYLMVGIEMEHFPEFENDVEF
TERLVAEQSVHCLPATCFEYPNFIRVVITVPEVMMLEACSRIQEFCEQHYHCAEGSQE
ECDK"
misc_feature 2070..2075
/note="minor mRNA polyadenylation signal"
polyA_site 2090..2090
/note="minor mRNA polyadenylation site"
repeat_region 2116..2130
/note="direct repeat flanking Alu element"
misc_feature complement(2131..2479)
/note="Alu element"
repeat_region 2480..2494
/note="direct repeat flanking Alu element"
misc_feature 2738..2743
/note="major mRNA polyadenylation signal"
polyA_site 2754..2754
/note="major mRNA polyadenylation site"
BASE COUNT 689 a 646 c 635 g 784 t
ORIGIN
1 attgcccctg taacctgtca aagaagagct aagggagctt tcggggttgg cttcttggag
61 gctgctttct cctttacttg gaaggcttcg ctagtgatgg acccatacat gattcagatg
121 agcagcaaag gcaacctccc ctcaattctg gacgtgcatg tcaacgttgg tgggagaagc
181 tctgtgccgg gaaaaatgaa aggcagaaag gccaggtggt ctgtgaggcc ctcagacatg
241 gccaagaaaa ctttcaaccc catccgagcc attgtggaca acatgaaggt gaaaccaaat
301 ccaaacaaaa ccatgatttc cctgtccatt ggggacccta ctgtgtttgg aaacctgcct
361 acagaccctg aagttaccca ggcaatgaaa gatgccctgg actcgggcaa atataatggc
421 tatgccccat ccatcggctt cctatccagt cgggaggaga ttgcttctta ttaccactgt
481 cctgaggcac ccctagaagc taaggacgtc attctgacaa gtggctgcag ccaagctatt
541 gacctttgtt tagctgtgtt ggccaaccca gggcagaaca tcctggttcc aagacctggt
601 ttctctctct acaagactct ggctgagtct atgggaattg aggtcaaact ctacaatttg
661 ttgccagaga aatcttggga aattgacctg aaacaactgg aatatctaat tgatgaaaag
721 acagcttgtc tcattgtcaa taatccatca aacccctgtg ggtcagtgtt cagcaaacgt
781 catcttcaga agattctggc agtggctgca cggcagtgtg tccccatctt agctgatgag
841 atctatggag acatggtgtt ttcggattgc aaatatgaac cactggccac cctcagcacc
901 gatgtcccca tcctgtcctg tggagggctg gccaagcgct ggctggttcc tggctggagg
961 ttgggctgga tcctcattca tgaccgaaga gacatttttg gcaatgagat ccgagatggg
1021 ctggtgaagc tgagtcagcg cattttggga ccctgtacca ttgtccaggg agctctgaaa
1081 agcatcctat gtcgcacccc gggagagttt taccacaaca ctctgagctt cctcaagtcc
1141 aatgctgatc tctgttatgg ggcgttggct gccatccctg gactccggcc agtccgccct
1201 tctggggcta tgtacctcat ggttggaatt gagatggaac atttcccaga atttgagaac
1261 gatgtggagt tcacggagcg gttagttgct gagcagtctg tccactgcct cccagcaacg
1321 tgctttgagt acccgaattt catccgagtg gtcatcacag tccccgaggt gatgatgctg
1381 gaggcgtgca gccggatcca ggagttctgt gagcagcact accattgtgc tgaaggcagc
1441 caggaggagt gtgataaata ggcctgcatc cattctcctg aggatgtgtc ccatctaggg
1501 aaggctggac taggccttgc ggctcctcag ggactcaggt ggccctactg ggagaggggc
1561 ctcaaatgca ccatgtcaag ggttcaagat tgttcctgct tttccccaag tacaaccaca
1621 cccacactca gatcctcctc attcacatcg cagattactc ccttgctctg cgctgctaga
1681 gtgactcact aattcattaa tctgcctccc tctcgtaaga tttccttctt ttttttcttg
1741 aaagtaccag gtgaacaaag tttaccagaa agcagttgag acaagaaaat aagagctcag
1801 gatgagggaa aagaaaaaga ttgagagaat ttgtgccccc aaccatttcc tcagactcta
1861 agaaagaaca cgctctctcc aggcaggtct gaagctcaac tctcttattg cctcacttca
1921 ggtatacctc actttacaca atagaattat aactggaaag aagttgggga cacatgtatt
1981 tggtgattac attttaaaca cattaggaaa agttgctatt tgaacttttt attgattttt
2041 ggggggagta aagaattatt ttggatgcaa ataaatatcc tttaattgat cgacttgcca
2101 aatttagatt tgtgtgcatc aggctttctt ttttttcttt ttttagagaa gttcaatata
2161 agcttttctt ttctttgttt ctttctttct ttattttgag atggagtctt gctctgtcgc
2221 ccatgctgga gtgcagtggc gcgatctcgg ctcactgcaa cctccacctc ctgggttcaa
2281 gcgattctct tgcctcaacc tcccaagcag ttgggactac aggcgtgagc caccatgccc
2341 ggctaatttt tgtattttta gtagagacag ggtttcacca tgttagccag gctggtctca
2401 aactcctgac ctcaggcaat ctgcccgcct gggtctccta aagtactggg attacaggcg
2461 tgagccacct cgcccagcgg catcaggctt tcttaaagtg agagcacgcc tgtactagag
2521 caagcaggaa tcagagacct tccagaaata ctactgtgta agggccagaa atatcttcac
2581 ttgtcattgt tatataatca ttattacttt tgctgtaatg ttaatattga tttattaata
2641 tatattatct tttcatacat tttctaagaa acatttatat tgataagatc ttttattttg
2701 caagggcata aattattgtt tttctttttt tttttttaat aaatttcacc aagt
//