LOCUS       X02162                   965 bp    mRNA    linear   HUM 07-OCT-2008
DEFINITION  Human mRNA for apolipoprotein AI (apo AI)=.
ACCESSION   X02162
VERSION     X02162.1
KEYWORDS    apolipoprotein; lipoprotein; signal peptide.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Seilhamer,J.J., Protter,A.A., Frossard,P. and  Levy-Wilson,B.
  TITLE     Isolation and DNA sequence of full-length cDNA and of the entire
            gene for human apolipoprotein AI--discovery of a new genetic
            polymorphism in the apo AI gene
  JOURNAL   DNA 3(4), 309-317(1984).
   PUBMED   6207999
FEATURES             Location/Qualifiers
     source          1..965
                     /db_xref="H-InvDB:HIT000320913_03"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     CDS             87..890
                     /product="preproapolipoprotein AI"
                     /db_xref="GOA:P02647"
                     /db_xref="H-InvDB:HIT000320913_03.4"
                     /db_xref="HGNC:HGNC:600"
                     /db_xref="InterPro:IPR000074"
                     /db_xref="PDB:1AV1"
                     /db_xref="PDB:1GW3"
                     /db_xref="PDB:1GW4"
                     /db_xref="PDB:1ODP"
                     /db_xref="PDB:1ODQ"
                     /db_xref="PDB:1ODR"
                     /db_xref="PDB:2A01"
                     /db_xref="PDB:3J00"
                     /db_xref="PDB:3K2S"
                     /db_xref="PDB:3R2P"
                     /db_xref="UniProtKB/Swiss-Prot:P02647"
                     /protein_id="CAA26097.1"
                     /translation="MKAAVLTLAVLFLTGSQARHFWQQDEPPQSPWDRVKDLATVYVD
                     VLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKE
                     TEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHE
                     LQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHA
                     KATEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLNTQ"
     sig_peptide     141..158
     mat_peptide     159..887
                     /product="apolipoprotein AI"
     polyA_signal    925..930
BASE COUNT          261 a          277 c          295 g          132 t
ORIGIN
        1 gaattcaaaa aaaaaagaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagag agactgcgag
       61 aaggaggtcc cccacggccc ttcaggatga aagctgcggt gctgaccttg gccgtgctct
      121 tcctgacggg gagccaggct cggcatttct ggcagcaaga tgaacccccc cagagcccct
      181 gggatcgagt gaaggacctg gccactgtgt acgtggatgt gctcaaagac agcggcagag
      241 actatgtgtc ccagtttgaa ggctccgcct tgggaaaaca gctaaaccta aagctccttg
      301 acaactggga cagcgtgacc tccaccttca gcaagctgcg cgaacagctc ggccctgtga
      361 cccaggagtt ctgggataac ctggaaaagg agacagaggg cctgaggcag gagatgagca
      421 aggatctgga ggaggtgaag gccaaggtgc agccctacct ggacgacttc cagaagaagt
      481 ggcaggagga gatggagctc taccgccaga aggtggagcc gctgcgcgca gagctccaag
      541 agggcgcgcg ccagaagctg cacgagctgc aagagaagct gagcccactg ggcgaggaga
      601 tgcgcgaccg cgcgcgcgcc catgtggacg cgctgcgcac gcatctggcc ccctacagcg
      661 acgagctgcg ccagcgcttg gccgcgcgcc ttgaggctct caaggagaac ggcggcgcca
      721 gactggccga gtaccacgcc aaggccaccg agcatctgag cacgctcagc gagaaggcca
      781 agcccgcgct cgaggacctc cgccaaggcc tgctgcccgt gctggagagc ttcaaggtca
      841 gcttcctgag cgctctcgag gagtacacta agaagctcaa cacccagtga ggcgcccgcc
      901 gccgcccccc ttcccggtgc tcagaataaa cgtttccaaa gtgggaaaaa aaaaaaaaag
      961 aattc
//