LOCUS HSU83115 6817 bp mRNA linear HUM 06-MAY-1997
DEFINITION Human non-lens beta gamma-crystallin like protein (AIM1) mRNA,
partial cds.
ACCESSION U83115
VERSION U83115.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6817)
AUTHORS Ray,M.E., Wistow,G., Su,Y.A., Meltzer,P.S. and Trent,J.M.
TITLE AIM1, a novel non-lens member of the betagamma-crystallin
superfamily, is associated with the control of tumorigenicity in
human malignant melanoma
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94 (7), 3229-3234 (1997)
PUBMED 9096375
REFERENCE 2 (bases 1 to 6817)
AUTHORS Ray,M.E., Meltzer,P.S. and Trent,J.M.
TITLE Direct Submission
JOURNAL Submitted (23-DEC-1996) NCHGR, NIH, 49 Convent Dr., Bethesda, MD
20892-4470, USA
FEATURES Location/Qualifiers
source 1..6817
/db_xref="H-InvDB:HIT000221812"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/tissue_type="liver"
gene 1..6817
/gene="AIM1"
CDS <1..4914
/gene="AIM1"
/note="encodes 12 tandem beta gamma-crystallin motifs;
absent in melanoma 1; similar to human beta/gamma
crystallin-like mRNA S6, deposited in GenBank Accession
Number U52051"
/codon_start=1
/product="non-lens beta gamma-crystallin like protein"
/protein_id="AAB53791.1"
/translation="QLRGESDRSKQPPPASSPTKRKGRSRALEAVPAPPASGPRAPAK
ESPPKRVPDPSPVTKGTAAESGEEAARAIPRELPVKSSSLLPEIKPEHKRGPLPNHFN
GRAEGGRSRELGRAAGAPGASDADGLKPRNHFGVGRSTVTTKVTLPAKPKHVELNLKT
PKNLDSLGNEHNPFSQPVHKGNTATKISLFENKRTNSSPRHTDIRGPRNTPASSKTFV
GRAKLNLAKKAKEMEQPEKKVMPNSPQNGVLVKETAIETKVTVSEEEILPATRGMNGD
SSENQALGPQPNQDDKADVQTDAGCLSEPVASALIPVKDHKLLEKEDSEAADSKSLVL
ENVTDTAQDIPTTVDTKDLPPTAMPKPQHTFSDSQSPAESSPGPSLSLSAPAPGDVPK
DTCVQSPISSFPCTDLKVSENHKGCVLPVSRQNNEKMPLLELGGETTPPLSTERSPEA
VGSECPSRVLVQVRSFVLPVESTQDVSSQVIPESSEVREVQLPTCHSNEPEVVSVASC
APPQEEVLGNEHSHCTAELAAKSGPQVIPPASEKTLPIQAQSQGSRTPLMAESSPTNS
PSSGNHLATPQRPDQTVTNGQDSPASLLNISAGSDDSVFDSSSDMEKFTEIIKQMDSA
VCMPMKRKKARMPNSPAPHFAMPPIHEDHLEKVFDPKVFTFGLGKKKESQPEMSPALH
LMQNLDTKSKLRPKRASAEQSVLFKSLHTNTNGNSEPLVMPEINDKENRDVTNGGIKR
SRLEKSALFSSLLSSLPQDKIFSPSVTSVNTMTTAFSTSQNGSLSQSSVSQPTTEGAP
PCGLNKEQSNLLPDNSLKVFNFNSSSTSHSSLKSPSHMEKYPQKEKTKEDLDSRSNLH
LPETKFSELSKLKNDDMEKANHIESVIKSNLPNCANSDTDFMGLFKSSRYDPSISFSG
MSLSDTMTLRGSVQNKLNPRPGKVVIYSEPDVSEKCIEVFSDIQDCSSWSLSPVILIK
VVRGCWILYEQPNFEGHSIPLEEGELELSGLWGIEDILERHEEAESDKPVVIGSIRHV
VQDYRVSHIDLFTEPEGLGILSSYFDDTEEMQGFGVMQKTCSMKVHWGTWLIYEEPGF
QGVPFILEPGEYPDLSFWDTEAAYIGSMRPLKMGGRKVEFPTDPKVVVYEKPFFEGKC
VELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYEKPGFTGHQYLLEE
GEYRDWKAWGGYNGELQSLRPILGDFSNAHMIMYSEKNFGSKGSSIDVLGIVANLKET
GYGVKTQSINVLSGVWVAYENPDFTGEQYILDKGFYTSFEDWGGKNYKISSVQPICLD
SFTGPRRRNQIHLFSEPQFQGHSQSFEETTSQIDDSFSTKSCRVSGGSWVVYDGENFT
GNQYVLEEGHYPCLSAMGCPPGATFKSLRFIDVEFSEPTIILFEREDFKGKKIELNAE
TVNLRSLGFNTQIRSVQVIGGIWVTYEYGSYRGRQFLLSPAEVPNWYEFSGCRQIGSL
RPFVQKRIYFRLRNKATGLFMSTNGNLEDLKLLRIQVMEDVGADDQIWIYQEGCIKCR
IAEDCCLTIVGSLVTSGSKLGLALDQNADSQFWSLKSDGRIYSKLKPNLVLDIKGGTQ
YDQNHIILNTVSKEKFTQVWEAMVLYT"
BASE COUNT 2008 a 1521 c 1521 g 1767 t
ORIGIN
1 cagctccgag gggagtcgga ccggagcaaa cagccacccc cggcttcgtc ccccacgaag
61 aggaagggca ggagccgtgc cctcgaggcc gtgcccgccc cgcccgccag cggcccccgg
121 gctcccgcca aggagtcccc acccaagagg gtgcccgatc ccagcccagt caccaagggc
181 actgcggccg agagcgggga ggaggcggcg cgggccatcc cccgcgagct cccggtcaag
241 agcagctcgc tgctgccgga gatcaagccc gagcacaaga ggggcccgct ccccaaccac
301 ttcaacggcc gggcagaggg aggtcgaagc agagagctgg gcagagcggc cggagcgcct
361 ggagcttctg acgccgacgg cttgaagccc aggaaccatt tcggcgtggg caggtcgaca
421 gtgaccacta aagtgaccct ccctgccaag cccaaacatg tggaactaaa tcttaaaacc
481 cctaagaatc ttgacagttt gggaaatgag cacaatccat ttagccagcc agttcacaaa
541 ggcaacactg ccaccaaaat ctccttattt gaaaacaaac ggacaaacag tagcccaaga
601 cacactgaca ttcgaggccc aaggaatact cctgcctcta gtaaaacgtt tgttgggagg
661 gcaaagctga atttagccaa aaaagccaaa gaaatggagc aacctgaaaa gaaagtaatg
721 ccaaacagtc cccagaatgg tgtgctggtt aaggaaactg ctatagaaac caaagttacc
781 gtctcggaag aagagattct gccagcaacc agaggaatga atggagactc ttctgagaat
841 caagctcttg gtcctcagcc taaccaagat gataaagcag atgtacaaac agatgctggc
901 tgcctttcag aaccagtggc ttctgctctg attcctgtca aggatcataa gctcttagag
961 aaggaggact cagaggctgc agacagcaaa agccttgtac ttgaaaatgt aaccgataca
1021 gcacaagaca tccccaccac tgtggatacc aaagatttac ctccaacggc catgccaaag
1081 ccacagcata cattttctga ctcacagtcc cctgctgagt catctcctgg gccttctctt
1141 tcactgtctg cacccgctcc tggggatgtt cccaaagaca catgtgttca atcacccata
1201 agcagtttcc catgcactga tctaaaagtg tcagaaaacc ataaaggatg tgttttgcct
1261 gtgtctcgtc agaacaatga gaaaatgcca cttttagaac ttggaggaga aacaacccct
1321 cctttgtcca cagagcgtag tccagaagct gtgggaagtg agtgtccatc cagagtcctc
1381 gtccaggtca ggtccttcgt gctccccgtg gagagcaccc aggatgtgag ctcccaggtc
1441 atcccagaga gctctgaagt tagagaagtg cagttgccaa cttgtcacag taatgaacct
1501 gaagtggttt ccgttgcaag ttgtgctccc ccacaagagg aagtactggg caatgaacac
1561 tctcattgca cagcagagct cgcggcaaaa tctggcccac aagtcatacc gccagcatca
1621 gagaaaactc tgcctattca ggctcaaagt cagggcagca gaacacccct gatggctgaa
1681 tccagtccca ccaactctcc cagcagcgga aatcacttag ccactcctca aaggccagat
1741 cagactgtta caaatggcca ggatagccct gccagccttt tgaacatttc tgctggtagt
1801 gatgatagtg tatttgattc ttcttctgat atggaaaaat tcactgaaat tataaaacag
1861 atggatagcg cagtttgtat gcccatgaaa agaaagaagg ccaggatgcc aaactctcct
1921 gctcctcact ttgccatgcc tcctattcac gaagaccatt tagaaaaggt gtttgatccc
1981 aaagtgttta cctttggttt ggggaagaag aaggaaagtc agccagaaat gtcaccggct
2041 ttacatttga tgcagaacct tgacacaaaa tccaaactga gacccaaacg tgcatctgct
2101 gaacagagcg tcctcttcaa gtccctgcac accaacacta atgggaacag tgagcctctg
2161 gtgatgccgg aaatcaatga caaagagaac agggacgtca caaatggtgg cattaagaga
2221 tcgagactag aaaaaagtgc acttttctca agcttgttat cttctttacc acaagacaaa
2281 atcttttctc cttctgtgac atcagtcaac actatgacca cggctttcag tacttctcag
2341 aacggttccc tatctcagtc ttcagtgtca cagcccacga ctgagggtgc cccgccctgt
2401 ggtttgaaca aagaacagtc aaatcttctg cccgacaact ccttaaaggt cttcaatttc
2461 aactcgtcaa gtacatcaca ctccagtttg aaaagtccaa gccacatgga aaaatacccg
2521 caaaaagaga aaaccaaaga agatctggat tcacgaagca acctacactt gccagaaact
2581 aaattttctg aattgtcaaa actgaagaat gatgatatgg aaaaggctaa tcatattgaa
2641 agtgttatta aatcaaactt gccaaactgt gcaaacagtg acaccgactt catgggtctt
2701 ttcaaatcaa gccggtatga cccaagcatt tctttttctg gaatgtcatt atcagacaca
2761 atgacactta gaggaagtgt ccaaaataaa ctcaatcccc gacctggaaa ggtagtgata
2821 tatagtgaac ccgacgtctc tgagaagtgc attgaagttt tcagtgacat tcaggattgc
2881 agttcttgga gcctctctcc agtgatactc ataaaagttg ttagaggatg ttggattttg
2941 tatgagcaac caaattttga agggcactcc atccccttag aagaaggaga attggaactc
3001 tctggtctct ggggtataga agacattttg gaaaggcacg aagaagcaga gtctgataag
3061 ccagtggtga ttggttccat cagacatgtg gttcaggatt acagagttag tcacattgac
3121 ttatttactg aaccagaagg gttaggaatc ctaagttcct actttgatga tactgaagaa
3181 atgcagggat ttggtgtaat gcagaagact tgttccatga aagtacattg gggcacgtgg
3241 ctgatttatg aagaacctgg atttcagggt gttcctttca tcctggaacc tggtgaatac
3301 cctgacttgt ccttctggga tacagaagca gcgtacattg gatccatgcg gcctctgaaa
3361 atgggtggcc gtaaagttga attccctaca gatccaaagg tagttgttta tgaaaagcct
3421 ttctttgaag gaaaatgtgt ggaactagaa acaggaatgt gtagttttgt catggaggga
3481 ggtgaaacag aagaggcgac tggagacgat catttgccgt ttacgtcagt ggggtctatg
3541 aaagttctaa gaggcatttg ggttgcatat gagaagcctg gatttaccgg tcatcagtat
3601 ttgctagaag aaggagaata cagggactgg aaagcctggg gaggttacaa tggagagctt
3661 cagtctttac gacctatatt aggtgatttt tcaaatgctc acatgataat gtacagtgaa
3721 aaaaactttg gatccaaagg ttccagtatt gatgtattgg gaattgttgc taatttaaag
3781 gagactggat atggagtgaa gacacagtct attaatgtac tgagtggagt atgggtagcc
3841 tatgaaaatc ctgacttcac aggagaacag tatatactgg ataaaggatt ttataccagt
3901 tttgaggact ggggaggcaa aaattataag atctcttctg ttcaacctat atgtttggat
3961 tctttcactg gcccaaggag acgaaatcag attcacttgt tttcagaacc acagtttcaa
4021 ggtcacagtc aaagttttga agaaacaaca agtcaaattg atgattcatt ttctaccaag
4081 tcttgcagag tttcaggagg cagctgggtt gtatatgatg gagaaaattt cactggtaat
4141 caatacgtgt tggaagaagg ccattatcct tgtctgtctg caatgggatg cccgcctgga
4201 gcaactttca agtctcttcg ttttatagat gttgaatttt ctgaaccaac aattattctc
4261 tttgaaagag aagacttcaa aggaaaaaag attgaactta atgcagaaac tgtcaatctc
4321 cgatccctgg gattcaacac acaaatacgc tctgttcagg ttattggtgg catatgggtt
4381 acttatgaat atggcagtta cagagggcga cagttcctat tgtcacctgc agaagtacct
4441 aattggtatg aattcagtgg ctgtcgccaa ataggttctc tacgaccttt tgttcagaag
4501 cgaatttatt tcagacttcg aaacaaagca acagggttat tcatgtcaac caatggaaac
4561 ttagaggatc tgaagcttct gaggatacag gtcatggagg atgtcggggc cgatgatcag
4621 atttggatct atcaagaagg atgtatcaaa tgcaggatag cagaagactg ctgcctgacg
4681 attgtgggca gcctggtaac atctggctcc aagctaggcc tggccctgga ccagaatgct
4741 gacagccagt tctggagctt gaagtccgat ggcaggattt acagcaagtt gaagccaaat
4801 ttagttttag acattaaagg gggcacacag tatgatcaaa atcacattat cctcaacact
4861 gtcagcaaag agaagtttac acaagtgtgg gaagccatgg tcctatatac ctgaacaaag
4921 aaggaagaag aatcttctgg aggtccttcc agccacctta tttcttaaaa aggacaatgc
4981 tgatggaaga ccagactgga aagtggatcg actcctcctt cattgattct aaattcaacc
5041 ttaaatcatg ctgccatgac tcagagaact tactcatcgt ttcaaaagac tatcatagct
5101 ttaaaccaat aatttgtcct cctttcattt cttgcctttc atttttggta gctgcttaaa
5161 caggttgcct aattagcagc ttttgggtga ttttgtaaaa tgttatatca agatttcaag
5221 actgtgtaca ttttaaatta tttccaaaga tagtgacagg agagaactgg aacaaattta
5281 ccaactttgt ggacctacaa agcccttaca ctttaaaggg taagacaaag gcttaagttt
5341 gaaaggtaga gaactgttta gcatctgaga agaaatactt tattaggcct gtaattttgg
5401 ttcttggcct taaacacttt ctggaacctt taaatatgct gcatagcaca atgggaaagc
5461 cttaggtatt cacacattta aggaactcta aacaaaatac tattttcctt tagttcatat
5521 taaaaattaa tacattttaa aaatttaatg tcaaagtctg gtaacatttg ttagtaggat
5581 ttgagttatt attttttgag acaggatctc aggctggagt gcagtggcac aatcacggct
5641 cactgcagcc tctacctccc caggctcagg tgatcctccc acctcagcct cccaagtagc
5701 tgggactata ggcacacatc accaagccca gccaaatttt gttttttttt tgtagagatg
5761 gggtttcatc acgttgccca ggctgatctc gaacctctgg gctcaagcaa ttcactcgcc
5821 tcggcctccc aaaatgctgg gattacaggc ctgagccact gcgcccagcc aggatttgaa
5881 ttattttaac tcatccatgg gctgccctag aatgtcacaa atgagggttg tttaatgcct
5941 ttcttatagc tgctactgga acactattat gacctaattt atgagccatc cttactcatc
6001 tacaagtgct gaagcaatgt tacatacttt tttgctaaac tcagattttt tagcctaatt
6061 tcttgtcctc ctatccacct gcatccacac atggcctgca tggggctgcc ttccctgcag
6121 tgttctgcag ccatgcttca gggtatagct gttggtggac agcctcaggt cttgggggca
6181 ctatagccac taaacgaggt gtgaaaggct caagaggatg accagcaatt aattatcccc
6241 agaaagtgaa ggaaaagaga cctttaggga tgttgctggt caagtcttga tttgaccgga
6301 gtcaaatcaa tcttcaagca atcttggaat cctcaactgc agtaagcatt tcaaaatgca
6361 aacaaactgc ttaacaactg acaagacacc agcccatatg ctgctcttcc aacagtgggt
6421 tctagctttg aacaaaagtg ctaaacattt ccttgaatat attcttcctc tttttgtcct
6481 catcactcaa tactggtgct cttgtcacag gtagaacagc ttgtttcttt tccatctatt
6541 caagtgtgtt tctaattcta aaatgctgat cttctctgga gtctatggta ggcaattatg
6601 gtcactggaa tagtttgtct tgttttaaaa tattattggt gcatgtacaa cagcatccaa
6661 catatctgtc ttgttcctag atatatagct ctgattttag gccttttgtg cataccatta
6721 caatatggtg gggtaagaca ttctacagta gcctgtgctg aactgatctc ttaaataaac
6781 ttgcttctgg ttaactaaaa aaaaaaaaaa aaaaaaa
//