LOCUS       HSU66075                2897 bp    mRNA    linear   HUM 17-JAN-1997
DEFINITION  Human transcription factor hGATA-6 mRNA, complete cds.
ACCESSION   U66075
VERSION     U66075.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2897)
  AUTHORS   Suzuki,E., Evans,T., Lowry,J., Truong,L., Bell,D.W., Testa,J.R. and
            Walsh,K.
  TITLE     The human GATA-6 gene: structure, chromosomal location, and
            regulation of expression by tissue-specific and mitogen-responsive
            signals
  JOURNAL   Genomics 38 (3), 283-290 (1996)
   PUBMED   8975704
REFERENCE   2  (bases 1 to 2897)
  AUTHORS   Evans,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-1996) Developmental and Molecular Biology, Albert
            Einstein College of Medicine, 1300 Morris Park Ave., Bronx, NY
            10461, USA
FEATURES             Location/Qualifiers
     source          1..2897
                     /db_xref="H-InvDB:HIT000220914"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
                     /map="18q1.1-1.2"
                     /clone_lib="heart"
                     /dev_stage="adult"
     CDS             348..1697
                     /function="transcription factor"
                     /note="expressed in heart, gut, and gut-derived tissues;
                     GATA-4, GATA-5 and GATA-6 are thought to be important for
                     regulating terminal differentiation and/or proliferation"
                     /codon_start=1
                     /product="hGATA-6"
                     /protein_id="AAC50941.1"
                     /db_xref="GI:1655915"
                     /translation="MYQTLAALSSQGPAAYDGAPGGFVHSAAAAAAAAAAASSPVYVP
                     TTRVGSMLPGLPYHLQGSGSGPANHAGGAGAHPGWPQASADSPPYGSGGGAAGGGAAG
                     PGGAGSAAAHVSARFPYSPSPPMANGAAREPGGYAAAGSGGAGGVSGGGSSLAAMGGR
                     EPQYSSLSAARPLNGTYHHHHHHHHHHPSPYSPYVGAPLTPAWPAGPFETPVLHSLQS
                     RAGAPLPVPRGPSADLLEDLSESRECVNCGSIQTPLWRRDGTGHYLCNACGLYSKMNG
                     LSRPLIKPQKRVPSSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRP
                     LAMKKEGIQTRKRKPKNINKSKTCSGNSNNSIPMTPTSTSSNSDDCSKNTSPTTQPTA
                     SGAGAPVMTGAGESTNPENSELKYSGQDGLYIGVSLASPAEVTSSVRPDSWCALALA"
BASE COUNT          657 a          857 c          764 g          619 t
ORIGIN      
        1 ggaattccgc gccgccttcc cccatctctt cctcgtcctc ctcctgctcc cggggcggag
       61 agcggggccc cggcggcgcc agcaactgcg ggacgcctca gctcgacacg gaggcggcgg
      121 ccggaccccc ggcccgctcg ctgctgctca gttcctacgc ttcgcatccc ttcggggctc
      181 cccacggacc ttcggcgcct ggggtcgcgg gccccggggg caacctgtcg agctgggagg
      241 acttgctgct gttcactgac ctcgaccaag ccgcgaccgc cagcaagctg ctgtggtcca
      301 gccgcggcgc caagctgagc cccttcgcac ccgagcagcc ggaggagatg taccagaccc
      361 tcgccgctct ctccagccag ggtccggccg cctacgacgg cgcgcccggc ggcttcgtgc
      421 actctgcggc cgcggcggca gcagccgcgg cggcggccag ctccccggtc tacgtgccca
      481 ccacccgcgt gggttccatg ctgcccggcc taccgtacca cctgcagggg tcgggcagtg
      541 ggccagccaa ccacgcgggc ggcgcgggcg cgcaccccgg ctggcctcag gcctcggccg
      601 acagccctcc atacggcagc ggtggcggcg cggctggcgg cggggccgcg gggcctggcg
      661 gcgctggctc agccgcggcg cacgtctcgg cgcgcttccc ctactctccc agcccgccca
      721 tggccaacgg cgccgcgcgg gagccgggag gctacgcggc ggcgggcagt gggggcgcgg
      781 gaggcgtgag cggcggcggc agtagcctgg cggccatggg cggccgcgag ccccagtaca
      841 gctcgctgtc ggccgcgcgg ccgctgaacg ggacgtacca ccaccaccac caccaccacc
      901 accaccatcc gagcccctac tcgccctacg tgggggcgcc actgacgcct gcctggcccg
      961 ccggaccctt cgagaccccg gtgctgcaca gcctgcagag ccgcgccgga gccccgctcc
     1021 cggtgccccg gggtcccagt gcagacctgc tggaggacct gtccgagagc cgcgagtgcg
     1081 tgaactgcgg ctccatccag acgccgctgt ggcggcggga cggcaccggc cactacctgt
     1141 gcaacgcctg cgggctctac agcaagatga acggcctcag ccggcccctc atcaagccgc
     1201 agaagcgcgt gccttcatca cggcggcttg gattgtcctg tgccaactgt cacaccacaa
     1261 ctaccacctt atggcgcaga aacgccgagg gtgaacccgt gtgcaatgct tgtggactct
     1321 acatgaaact ccatggggtg cccagaccac ttgctatgaa aaaagaggga attcaaacca
     1381 ggaaacgaaa acctaagaac ataaataaat caaagacttg ctctggtaat agcaataatt
     1441 ccattcccat gactccaact tccacctctt ctaactcaga tgattgcagc aaaaatactt
     1501 cccccacaac acaacctaca gcctcagggg cgggtgcccc ggtgatgact ggtgcgggag
     1561 agagcaccaa tcccgagaac agcgagctca agtattcggg tcaagatggg ctctacatag
     1621 gcgtcagtct cgcctcgccg gccgaagtca cgtcctccgt gcgaccggat tcctggtgcg
     1681 ccctggccct ggcctgagcc cacgccgcca ggaggcaggg agggctccgc cgcgggcctc
     1741 actccactcg tgtctgcttt tgtgcagcgg tccagacagt ggcgactgcg ctgacagaac
     1801 gtgattctcg tgcctttatt ttgaaagaga tgtttttccc aagaggcttg ctgaaagagt
     1861 gagagaagat ggaagggaag ggccagtgca actgggcgct tgggccactc cagccagccc
     1921 gcctccgggg cggaccctgc tccacttcca gaagccagga ctaggacctg ggccttgcct
     1981 gctatggaat attgagagag attttttaaa aaagattttg cattttgtcc aaaatcatgt
     2041 gcttcttctg atcaattttg gttgttccag aatttcttca taccttttcc acatccagat
     2101 ttcatgtgcg ttcatggaga agatcacttg aggccatttg gtacacatct ctggaggctg
     2161 agtcggttca tgaggtctct tatcaaaaat attactcagt ttgcaagact gcattgtaac
     2221 tttaacatac actgtgactg acgtttctca aagttcatat tgtgtggctg atctgaagtc
     2281 agtcggaatt tgtaaacagg gtagcaaaca agatattttt cttccatgta tacaataatt
     2341 tttttaaaaa gtgcaatttg cgttgcagca atcagtgtta aatcatttgc ataagattta
     2401 acagcatttt ttataatgaa tgtaaacatt ttaacttaat ggtacttaaa ataatttaaa
     2461 agaaaaatgt taacttagac attcttatgc ttcttttaca actacatccc attttatatt
     2521 tccaattgtt aaagaaaaat atttcaagaa caaatcttct ctcaggaaaa ttgcctttct
     2581 ctatttgtta agaattttta tacaagaaca ccaatatacc ccctttattt tactgtggaa
     2641 tatgtgctgg aaaaattgca acaacacttt actacctaac ggatagcatt tgtaaatact
     2701 ctaggtatct gtaaacactc tgatgaagtc tgtatagtgt gactaaccca caggcaggtt
     2761 ggtttacatt aatttttttt ttgaatggga tgtcctatgg aaacctattt caccagagtt
     2821 ttaaaaataa aaagggtatt gttttgtctt ctgtaaaaaa aaaaaaaaaa aaaaaaaaaa
     2881 aaaaaaaaaa aaaaaaa
//