LOCUS       HSU56438               12177 bp    DNA     linear   HUM 07-NOV-1996
DEFINITION  Human dioxin-inducible cytochrome P450 (CYP1B1) gene, complete cds.
ACCESSION   U56438
VERSION     U56438.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 12177)
  AUTHORS   Sutter,T.R., Tang,Y.M., Hayes,C.L., Wo,Y.Y., Jabs,E.W., Li,X.,
            Yin,H., Cody,C.W. and Greenlee,W.F.
  TITLE     Complete cDNA sequence of a human dioxin-inducible mRNA identifies
            a new gene subfamily of cytochrome P450 that maps to chromosome 2
  JOURNAL   J. Biol. Chem. 269 (18), 13092-13099 (1994)
   PUBMED   8175734
REFERENCE   2  (bases 1 to 12177)
  AUTHORS   Tang,Y.M., Wo,Y.Y., Stewart,J., Hawkins,A.L., Griffin,C.A.,
            Sutter,T.R. and Greenlee,W.F.
  TITLE     Isolation and characterization of the human cytochrome P450 CYP1B1
            gene
  JOURNAL   J. Biol. Chem. 271 (45), 28324-28330 (1996)
   PUBMED   8910454
REFERENCE   3  (bases 1 to 12177)
  AUTHORS   Greenlee,W.F.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-APR-1996) Pharmacology & Mol. Toxicology, U. Mass.
            Med. Center, 55 Lake Ave North, Worcester, MA 01655, USA
FEATURES             Location/Qualifiers
     source          1..12177
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p21-22"
     mRNA            join(3070..3414,3805..4848,7881..11587)
                     /gene="CYP1B1"
                     /product="dioxin-inducible cytochrome P450"
     gene            join(3806..4848,7881..8469)
                     /gene="CYP1B1"
     CDS             join(3806..4848,7881..8469)
                     /gene="CYP1B1"
                     /codon_start=1
                     /product="dioxin-inducible cytochrome P450"
                     /protein_id="AAC50809.1"
                     /translation="MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRR
                     RQLRSAPPGPFAWPLIGNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERA
                     IHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQP
                     RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDD
                     PEFRELLSHNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKF
                     LRHCESLRPGAAPRDMMDAFILSAEKKAAGDSHGGGARLDLENVPATITDIFGASQDT
                     LSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFS
                     SFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPLKWPNPENFDPARFLDKDG
                     LINKDLTSRVMIFSVGKRRCIGEELSKMQLFLFISILAHQCDFRANPNEPAKMNFSYG
                     LTIKPKSFKVNVTLRESMELLDSAVQNLQAKETCQ"
BASE COUNT         3238 a         2803 c         2832 g         3304 t
ORIGIN      
        1 gagctcaatt aaccctcact aaagggagtc gactcgatct aaaaactaga tggcattatt
       61 gaggagttgg acaggcggtc ttaggaacaa cctcgtttta tactttttaa aaataggaat
      121 ttacttaaag gcaacttcca tctgctctca ttctggcaga ggtattgtga taaaggcttt
      181 caggaatgtc aacagctcag gattggcatt agctcataga taattcccgt ctactaaatt
      241 aaagtctatg agagattgat gcatgcacca gagtcttgaa ttattaggca aggatcttgc
      301 taaagctgga catgggaagg ttgctatgaa actcatttca aaggctgtgt aggccaactc
      361 acctctggga aaccaacgct tattattaaa ccaatgcaac tgctcaaaaa ctaaaactcc
      421 atcactatct aagttcccca tcatggtgtg tgaaatcatt tccagaaaac tcttcaaaag
      481 ataccgaata aaaggcatca caggccgggc acggtggctc atgcctgtaa tcccagcact
      541 ttgggaggcc caggctggtg gatcacctga ggtcaggagt ttgagaccag cctggccagc
      601 atggtgaaac cccatctcta ctagaaaaat acaaaaatta gccgggtgtg gtggtgcgca
      661 cctgtaatcc cagctacttg ggaggctgag ccaggagaac ctggcaggcg gaggttgcag
      721 tgagccgaga tcacgccatt gcactgcagc ccaggtgaca gagtgagact ccatctcaaa
      781 aaaaataaat aaataaaaat aaaaataaaa aaagccatca cgaaaagaca tttctttatc
      841 aggtcagcaa attgattgct ggtttcaatc tctcaagaag tcagattctc ttcagacact
      901 cctttgtgtt tctttacaat gtaatcagtc attccagggt cagctatgag gcacactccc
      961 ctggcctccc tcataagcaa tttaattgca aagggttagc atactatttc ttctctgcta
     1021 ttctcagaat tctcaattat gaaaacaaaa acaataatta aaaagttctt ccagctgatt
     1081 tttttttttt tttttgagac agagtctcac ttaaactctg ctgcccaggc tgtagtgcag
     1141 tggtgcaatc tctgctcact gcaacctctg cctcccacgt tcaaccaatt ctgctgcctt
     1201 cccccctgat ccccgagtag ctgggattac aggtgtgcac caccacgtcc ggctaacttt
     1261 tgtattttta gtagatgggg tttcgccatg ttggccaggc tggtctcgaa ctcctgacct
     1321 caagtgatcc gcccgcttaa gcctcccaaa gtgctgggat tacaggcgtg agccactgcg
     1381 cctagcccca cgtgcatttt ttttttttta agggaggcag gaaagaaggc atttgggcct
     1441 cttatctgca attttcttcc gtgtaaactt atgtgaagga tctggagtgg gacttggtgg
     1501 cttcaagccc tggctccact tcttgatggc tgcgcgacct gggttaagtc acgcaacctc
     1561 tctgaaccct agtttattca tctgtaaaca ggtcaataat agcacgagat tgcagcgcga
     1621 gtggagctca aagtgcaggg ttgtccctgg tgaacctatc acttttatat ttatcctttg
     1681 atgaagccag tacaattcct acctggttaa ccagatacat cccacctctt ccctcgagtt
     1741 cgcccttccc cccgcctcgt gaagtccttg ttctcttagc tgtcttgaaa atcctatgca
     1801 tcagcatgta ggaaagggcg cgccaggcgg gggaagccac ccccgcccga gcgcctccgg
     1861 ttcccttata aagggagggc ccccttcgcg accgcaagcg cgcccaggaa gaccacagag
     1921 ccgccggtgc gcacggaggt ggcgatacgc gcccgggctc ggcctgcggg tggtggccca
     1981 agcgtccgcc tcgctggcct ggcaggcgcg actgtgcgtg cgcagccgag ggtggtggcg
     2041 gccggcaccc cacgccaagg gtggtggtgg ccggcacccc accctcggcc gccgcctccg
     2101 cgtgtcaggt gccgtgagaa gcgcgggagg agcggccgca ggcagcgccc agggatatga
     2161 ctggagccga ctttccagaa gcggcgcacg caaagcccag ctccgcacgc aaaggggagg
     2221 cgacacgaga aacttcaacc cgataaagtt cgccggagcg cggagattcg cctcctcctg
     2281 ccactctccg ccccgctcgg gtcccgcccc gctagctccc ccaggccccc ccagtcgccc
     2341 cagcttggct ccccgccctg cgccaacggc ttccatcgca gcctgggcgg ccccgcgccc
     2401 accagcgggc ggcgccacct ggagtggcct ctacgcggga aatctcaggg ccagctgcgc
     2461 cccaggagcc tttgtgtgcc caagcactgt cggggccccg gggcggggga gcggctactt
     2521 ttagggattc ctgatctcgc cgcaagaact ggaaaaaatt tagcatgcca aagagcctcc
     2581 actgaggtgg caatttgttt gcgagaacct aagataaaat ttaaacaacc aaccaggggc
     2641 gctgtgaggc aaaccgctgc cactacactg gctttccggg aagcaagctc aagccgcgga
     2701 gagggaaggg aggtcgtgcg ctcggggcgg ggcgcgctcc caagtcgagc gcagcggccg
     2761 gggcaggttg taccgagcgt ggttctgggg acaccgtgcg gccttgattg gaggtggctg
     2821 tgatgaagcg cggttaccgc acaatggaaa cgtgggcacc tccgctccca tgaaagcctg
     2881 ctggtagagc tccgaggccg gccggtgcgc ctggacggga gtccgggtca aagcggcctg
     2941 gtgtgcggcg cgccccgccc cccgcaggcc ccgccctgcc aggtcgcgct gccctccttc
     3001 tacccagtcc ttaaaacccg gaggagcggg atggcgcgct ttgactctgg agtgggagtg
     3061 ggagcgagcg cttctgcgac tccagttgtg agagccgcaa gggcatggga attgacgcca
     3121 ctcaccgacc cccagtctca atctcaacgc tgtgaggaaa cctcgacttt gccaggtccc
     3181 caagggcagc ggggctcggc gagcgaggca cccttctccg tccccatccc aatccaagcg
     3241 ctcctggcac tgacgacgcc aagagactcg agtgggagtt aaagcttcca gtgagggcag
     3301 caggtgtcca ggccgggcct gcgggttcct gttgacgtct tgccctaggc aaaggtccca
     3361 gttccttctc ggagccggct gtcccgcgcc actggaaacc gcacctcccc gcaggtcagt
     3421 ctgtctgccg aggcgctgcc cggcgacctc ttcagatgga ttattacagg tagcgggtgg
     3481 cgtggtaggt actttaaagg aaatcaagcg ccaccgcctc gatgcccgca gcgttgtccc
     3541 caaattgcag gaaccgttac gcgccttgcg gggaggggaa gggtttggcg ctgggttaca
     3601 gcgaggtgga aacacgcccc ttctcttctc caagggagag tgggttgggg atgggaaggg
     3661 gcgtcttcgg ccatttctcc agagagtcag ctccgacctc tccacccaac ggcactcagt
     3721 ccccagaggc tggggtaggg gcgtggggcg cccgctcctg tctctgcacc cctgagtgtc
     3781 acgccttctc ctttctgtcc ccagcatggg caccagcctc agcccgaacg acccttggcc
     3841 gctaaacccg ctgtccatcc agcagaccac gctcctgcta ctcctgtcgg tgctggccac
     3901 tgtgcatgtg ggccagcggc tgctgaggca acggaggcgg cagctccggt ccgcgccccc
     3961 gggcccgttt gcgtggccac tgatcggaaa cgcggcggcg gtgggccagg cggctcacct
     4021 ctcgttcgct cgcctggcgc ggcgctacgg cgacgttttc cagatccgcc tgggcagctg
     4081 ccccatagtg gtgctgaatg gcgagcgcgc catccaccag gccctggtgc agcagggctc
     4141 ggccttcgcc gaccggccgg ccttcgcctc cttccgtgtg gtgtccggcg gccgcagcat
     4201 ggctttcggc cactactcgg agcactggaa ggtgcagcgg cgcgcagccc acagcatgat
     4261 gcgcaacttc ttcacgcgcc agccgcgcag ccgccaagtc ctcgagggcc acgtgctgag
     4321 cgaggcgcgc gagctggtgg cgctgctggt gcgcggcagc gcggacggcg ccttcctcga
     4381 cccgaggccg ctgaccgtcg tggccgtggc caacgtcatg agtgccgtgt gtttcggctg
     4441 ccgctacagc cacgacgacc ccgagttccg tgagctgctc agccacaacg aagagttcgg
     4501 gcgcacggtg ggcgcgggca gcctggtgga cgtgatgccc tggctgcagt acttccccaa
     4561 cccggtgcgc accgttttcc gcgaattcga gcagctcaac cgcaacttca gcaacttcat
     4621 cctggacaag ttcttgaggc actgcgaaag ccttcggccc ggggccgccc cccgcgacat
     4681 gatggacgcc tttatcctct ctgcggaaaa gaaggcggcc ggggactcgc acggtggtgg
     4741 cgcgcggctg gatttggaga acgtaccggc cactatcact gacatcttcg gcgccagcca
     4801 ggacaccctg tccaccgcgc tgcagtggct gctcctcctc ttcaccaggt aaagcctctg
     4861 ggaggcgtgg gccaggtctt ttctcctctg aaaaaggcgg agtagagaca gaatatgctg
     4921 agtttgcaag cagggccccg ggtttggggt ttcgctccag gtccccaccc ctcaaaacca
     4981 agatcgcgtc ggtaaaggga ctcacagtga gggctgcgac acgcacgcgc cccacccagc
     5041 ggtgccccga cccctccggt ctcctatctt gtctctatcg tcccctcccc tgcttgcgag
     5101 tgagaacaca tttgcaaaga cccctccacc ccccgggaaa aacaagagtt tttaaatgct
     5161 tggagatgag ccctgatatc tctctccctg gcgcattaca atcagaactg gaatagttcc
     5221 gaaagaaaag gtaatgtcat aaatatgtta aacacagcag cctctcctag gctagtcctc
     5281 ggcgtgcatc cgaggccgcc cagccctggc gctaaaagcg ggccgcccgt cagggctttg
     5341 ttccaggcca aggaagccca tggaggccgg gccagccgac aggtaacccg cacagaaact
     5401 ttcagaaggc ggccacaact agcgggcagc gctaggttta taaaacctcc gcgctaggag
     5461 tttgagaaat gccggggtag aagacaagaa gcagtcactt ttacgaaagc agagtagcat
     5521 tcagaaaggc agatgggata tccaggaggc gcctgcagac gtttctggcc cctgcgcttg
     5581 gctcagttag cggaccccct gatgcccacg ttggtctcta ctaagcacgg attcaacagg
     5641 tccctggtgt cgggttgcca gatttggcaa aagaaaagta agttttacac gggaatactc
     5701 acactaaaag attagccctt gttgatctga aatccatatt taactgggcg gcctgtagta
     5761 tttactgtgg aaacactatc cctaggggca aatgtttcgc aaggcaaatt ttgattgccg
     5821 aagagaccag aaatcctggt tttgtgtcat ttcttggagc acaagtgagc agttggagat
     5881 gctgaatctg caggcgccac agaaaggtgt ttggaaggca gagaatgact ctttccttat
     5941 taaaatccac tgcaatctat atttccttag atactgtaca gctaccttca caaattaaaa
     6001 gtttctgtat acttaaaatg gctttttagt attaaaatca tagaaacacc catggtgggt
     6061 gagggagagg cagaaatcga ataaagaaaa gtcaaccaga gatcagggaa aaggaaatcc
     6121 cggaataggt tccataggtt tttgtgcatc cgcagatagg cattttaact tttgaaacgg
     6181 cctttgtttt tcattagaac cacaatagtt ctccgagtac tccaattagg cggcaaaaag
     6241 aaataaaaca atttggaggt cactttcaat tcaatatgct gatacttttt tttccttttt
     6301 agtgaaaaga cgtatgacag ggcttggcaa attacacgat ctgtttttgt atatacgttt
     6361 tattgacgca gtcatgccca ttcatttata cattgtcgat ggctgcgttc actctacaac
     6421 acaaggcaga gcagagtagt gcaacaaaga gggtttggtc cacaaagtct aaaatagata
     6481 ctctctggct ctccccacca tacatgtttc tatgaaaaaa gttggcagac tcctgcaata
     6541 taatgttgaa gaagcgattc taaaaataac tccacttcat cacatacgtg tatacatttt
     6601 ttttcggagt tgcaaacaat cagttacttg ttttttgact tctaacactt tgactcaagg
     6661 tagtggacat ttctaatctt ttaatattta ttttggtaat ttttgatggc tatatagtat
     6721 tttgctatga taatgtatag ttatatataa tcatttattg aactttaatg ttggtcattg
     6781 gccttgattg catttttaaa atttttattt taattttatg tatttactta ccttagagac
     6841 agggtctcac taccttaccc aggctggtcc caaactcctg ggctcaagca gttctcccgc
     6901 cgctgtctgg caggtagctg gggctacagg cgtgtaccac catgcctggc taatttttag
     6961 aattttaggt cctgttgtgg ttacatattt ttgtatctct taaattattt tctgaaaata
     7021 catttctagg catggattac tgggtttaaa atgaggcggg aagaggttac cttcatgtct
     7081 cttgcctcgt attaagattt tgttttttaa aaagattgta tcagtttgta tcatcaacag
     7141 tgaataagta ctacagtttg taccataatt ttatgaacat tgggtatttg ctttcaaatt
     7201 taaaaaatac agtatgtagc tttatccatc aggacaccaa ttatctttgt ataaaatgag
     7261 aacagcatgt ctgttggaat tgtccaggga aatgagggag aaaaaaaatt tactttcaca
     7321 ttgtaacttt cgtgggccct gggtgctttt gcctttgtag attccttata ctataaaaaa
     7381 attaaaaatt aaatttcatg actaccctga tataaagatg aatgcattaa aatgatgtat
     7441 gaaaatattt tcttctacct aaaagtgagt ttttttaggt ctgaagattg taaaagacgt
     7501 aaaaatattt tcatgggccc ctaaaaagtg ttgtgagccc taggcactgt cctgcggtac
     7561 ccaatggaaa agtcagcctt atctactatt gtgctttttg aggctgggaa aacttaagag
     7621 ttttttgact tataatggga aagacagcat tagtcatgca aggcctatta caggaaatat
     7681 aattcttaaa gtccatcttg taatttagtg agaaattagg aagctgtttt agattttttt
     7741 cccagaaata ttaatttagt cactgagcta gatagcctat ttaagaaaaa gtggaattaa
     7801 aataaattat aatgtgcttt ctagatgaaa taagaatttt gctcacttgc ttttctctct
     7861 ccacattaaa caccaaacag gtatcctgat gtgcagactc gagtgcaggc agaattggat
     7921 caggtcgtgg ggagggaccg tctgccttgt atgggtgacc agcccaacct gccctatgtc
     7981 ctggccttcc tttatgaagc catgcgcttc tccagctttg tgcctgtcac tattcctcat
     8041 gccaccactg ccaacacctc tgtcttgggc taccacattc ccaaggacac tgtggttttt
     8101 gtcaaccagt ggtctgtgaa tcatgaccca ctgaagtggc ctaacccgga gaactttgat
     8161 ccagctcgat tcttggacaa ggacggcctc atcaacaagg acctgaccag cagagtgatg
     8221 attttttcag tgggcaaaag gcggtgcatt ggcgaagaac tttctaagat gcagcttttt
     8281 ctcttcatct ccatcctggc tcaccagtgc gatttcaggg ccaacccaaa tgagcctgcg
     8341 aaaatgaatt tcagttatgg tctaaccatt aaacccaagt catttaaagt caatgtcact
     8401 ctcagagagt ccatggagct ccttgatagt gctgtccaaa atttacaagc caaggaaact
     8461 tgccaataag aagcaagagg caagctgaaa ttttagaaat attcacatct tcggagatga
     8521 ggagtaaaat tcagtttttt tccagttcct cttttgtgct gcttctcaat tagcgtttaa
     8581 ggtgagcata aatcaactgt ccatcaggtg aggtgtgctc catacccagc ggttcttcat
     8641 gagtagtggg ctatgcagga gcttctggga gatttttttg agtcaaagac ttaaagggcc
     8701 caatgaatta ttatatacat actgcatctt ggttatttct gaaggtagca ttctttggag
     8761 ttaaaatgca catatagaca catacaccca aacacttaca ccaaactact gaatgaagaa
     8821 gtattttggt aaccaggcca tttttggtgg gaatccaaga ttggtctccc atatgcagaa
     8881 atagacaaaa agtatattaa acaaagtttc agagtatatt gttgaagaga cagagacaag
     8941 taatttcagt gtaaagtgtg tgattgaagg tgataaggga aaagataaag accagaaatt
     9001 cccttttcac cttttcagga aaataactta gactctagta tttatgggtg gatttatcct
     9061 tttgccttct ggtatacttc cttactttta aggataaatc ataaagtcag ttgctcaaaa
     9121 agaaatcaat agttgaatta gtgagtatag tggggttcca tgatttatca tgaattttaa
     9181 agtatgcatt attaaattgt aaaactccaa ggtgatgttg tacctctttt gcttgccaaa
     9241 gtacagaatt tgaattatca gcaaagaaaa aaaaaaaagc cagccaagct ttaaattatg
     9301 tgaccataat gtactgattt cagtaagtct cataggttaa aaaaaaaagt caccaaatag
     9361 tgtgaaatat attacttaac tgtccgtaag cagtatatta gtattatctt gttcaggaaa
     9421 aggttgaata atatatgcct tgtgtaatat tgaaaattga aaagtacaac taacgcaacc
     9481 aagtgtgcta aaaatgagct tgattaaatc aaccacctat ttttgacatg gaaatgaagc
     9541 agggtttctt ttcttcactc aaattttggc gaatctcaaa attagatcct aagatgtgtt
     9601 cttattttta taacatcttt attgaaattc tatttataat acagaatctt gttttgaaaa
     9661 taacctaatt aatatattaa aattccaaat tcatggcatg cttaaatttt aactaaattt
     9721 taaagccatt ctgattattg agttccagtt gaagttagtg gaaatctgaa cattctcctg
     9781 tggaaggcag agaaatctaa gctgtgtctg cccaatgaat aatggaaaat gccatgaatt
     9841 acctggatgt tctttttacg aggtgacaag agttggggac agaactccca ttacaactga
     9901 ccaagtttct cttctagatg attttttgaa agttaacatt aatgcctgct ttttggaaag
     9961 tcagaatcag aagatagtct tggaagctgt ttggaaaaga cagtggagat gaggtcagtt
    10021 gtgtttttta agatggcaat tactttggta gctgggaaag cataaagctc aaatgaaatg
    10081 tatgcattca catttagaaa agtgaattga agtttcaagt tttaaagttc attgcaatta
    10141 aacttccaaa gaaagttcta cagtgtccta agtgctaagt gcttattaca ttttattaag
    10201 ctttttggaa tctttgtacc aaaattttaa aaaagggagt ttttgatagt tgtgtgtatg
    10261 tgtgtgtggg gtggggggat ggtaagagaa aagagagaaa cactgaaaag aaggaaagat
    10321 ggttaaacat tttcccactc attctgaatt aattaatttg gagcacaaaa ttcaaagcat
    10381 ggacatttag aagaaagatg tttggcgtag cagagttaaa tctcaaatag gctattaaaa
    10441 aagtctacaa catagcagat ctgttttgtg gtttggaata ttaaaaaact tcatgtaatt
    10501 ttattttaaa atttcatagc tgtacttctt gaatataaaa aatcatgcca gtatttttaa
    10561 aggcattaga gtcaactaca caaagcaggc ttgcccagta catttaaatt ttttggcact
    10621 tgccattcca aaatattatg ccccaccaag gctgagacag tgaatttggg ctgctgtagc
    10681 ctattttttt agattgagaa atgtgtagct gcaaaaataa tcatgaacca atctggatgc
    10741 ctcattatgt caaccaggtc cagatgtgct ataatctgtt tttacgtatg taggcccagt
    10801 cgtcatcaga tgcttgcggc aaaagaaagc tgtgtttata tggaagaaag taaggtgctt
    10861 ggagtttacc tggcttattt aatatgctta taacctagtt aaagaaagga aaagaaaaca
    10921 aaaaacgaat gaaaataact gaatttggag gctggagtaa tcagattact gctttaatca
    10981 gaaaccctca ttgtgtttct accggagaga gaatgtattt gctgacaacc attaaagtca
    11041 gaagttttac tccaggttat tgcaataaag tataatgttt attaaatgct tcatttgtat
    11101 gtcaaagctt tgactctata agcaaattgc ttttttccaa aacaaaaaga tgtctcaggt
    11161 ttgttttgtg aattttctaa aagctttcat gtcccagaac ttagccttta cctgtgaagt
    11221 gttactacag ccttaatatt ttcctagtag atctatatta gatcaaatag ttgcatagca
    11281 gtatatgtta atttgtgtgt ttttagctgt gacacaactg tgtgattaaa aggtatactt
    11341 tagtagacat ttataactca aggatacctt cttatttaat cttttcttat ttttgtactt
    11401 tatcatgaat gcttttagtg tgtgcataat agctacagtg catagttgta gacaaagtac
    11461 attctgggga aacaacattt atatgtagcc tttactgttt gatataccaa attaaaaaaa
    11521 aattgtatct cattacttat actgggacac cattaccaaa ataataaaaa tcactttcat
    11581 aatcttgtta tgaagtttta tgttgtagca aatatagtct aatgtatcac tttatttcaa
    11641 ctattactat ggattattca attaaaatat tgcactgtaa acattttatt tgtccattct
    11701 acatttcagg ccgaggccac atgctttttt ttcccgtagg ttttcatcaa ccaaatttct
    11761 aatctctata tttttgaatt tctaagaacc aacacggagg ttacatttca atcaaacaat
    11821 caagccaaat gagaattaat ttgcaatgtt gaaagattga atagattgcg actttaagtt
    11881 gctgatcgat ttctgcttca tctaaagaat gcagtacaca tttttcttcc tcagcctcat
    11941 accagtcctt tctctgagta ttttcttctt tcattttttt aaaggtacat gtgcctcaat
    12001 tagtgcaatt aatgtccaat aaaataagat gggtacaagt attctgtcat gtactatgtg
    12061 gaaatgtttt attgccaatc tttttacttg gtaaaaatac ttgacttcac agggcctagg
    12121 tcatgactct ccaggccttc actgtgccac actcacagat gacagggctt gcggtac
//