LOCUS       HUMTROPIA                706 bp    mRNA    linear   HUM 28-JAN-1994
DEFINITION  Human cardiac troponin I mRNA, complete cds.
ACCESSION   M64247
VERSION     M64247.1
KEYWORDS    troponin I.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (sites)
  AUTHORS   Vallins,W.J., Brand,N.J., Dabhade,N., Butler-Browne,G., Yacoub,M.H.
            and Barton,P.J.
  TITLE     Molecular cloning of human cardiac troponin I using polymerase
            chain reaction
  JOURNAL   FEBS Lett. 270 (1-2), 57-61 (1990)
   PUBMED   2226790
REFERENCE   2  (bases 1 to 706)
  AUTHORS   Armour,K.L. and Tempest,P.R.
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 706)
  AUTHORS   Armour,K.L., Harris,W.J. and Tempest,P.R.
  TITLE     Cloning and expression in Escherichia coli of the cDNA encoding
            human cardiac troponin I
  JOURNAL   Gene 131 (2), 287-292 (1993)
   PUBMED   8406024
REFERENCE   4  (bases 1 to 706)
  AUTHORS   Tempest,P.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-1991) P.R. Tempest, ICOS Corporation, 2201 20th
            Ave. S.E., Bothell, WA 98021, USA
COMMENT     Original source text: Human, cDNA to mRNA.
FEATURES             Location/Qualifiers
     source          1..706
                     /db_xref="H-InvDB:HIT000196104"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     gene            1..706
                     /gene="TNNI3"
     5'UTR           <1..8
                     /gene="TNNI3"
     CDS             9..641
                     /gene="TNNI3"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /citation=[2]
                     /codon_start=1
                     /product="cardiac troponin I"
                     /protein_id="AAA16157.1"
                     /db_xref="GI:339967"
                     /translation="MADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISAS
                     RKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHA
                     RVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLG
                     ARAKESLDLRAHLKQVKKEDTEKENREVGDWRKNIDALSGMEGRKKKFES"
     conflict        264
                     /gene="TNNI3"
                     /note="a in conflict"
                     /citation=[1]
                     /citation=[2]
     conflict        584
                     /gene="TNNI3"
                     /note="g in conflict"
                     /citation=[1]
                     /citation=[2]
     3'UTR           642..>642
                     /gene="TNNI3"
     conflict        678
                     /gene="TNNI3"
                     /note="ac in conflict"
                     /citation=[1]
                     /citation=[2]
BASE COUNT          176 a          190 c          232 g          108 t
ORIGIN      
        1 gtctcagcat ggcggatggg agcagcgatg cggctaggga acctcgccct gcaccagccc
       61 caatcagacg ccgctcctcc aactaccgcg cttatgccac ggagccgcac gccaagaaaa
      121 aatctaagat ctccgcctcg agaaaattgc agctgaagac tctgctgctg cagattgcaa
      181 agcaagagct ggagcgagag gcggaggagc ggcgcggaga gaaggggcgc gctctgagca
      241 cccgctgcca gccgctggag ttggccgggc tgggcttcgc ggagctgcag gacttgtgcc
      301 gacagctcca cgcccgtgtg gacaaggtgg atgaagagag atacgacata gaggcaaaag
      361 tcaccaagaa catcacggag attgcagatc tgactcagaa gatctttgac cttcgaggca
      421 agtttaagcg gcccaccctg cggagagtga ggatctctgc agatgccatg atgcaggcgc
      481 tgctgggggc ccgggctaag gagtccctgg acctgcgggc ccacctcaag caggtgaaga
      541 aggaggacac cgagaaggaa aaccgggagg tgggagactg gcgcaagaac atcgatgcac
      601 tgagtggaat ggagggccgc aagaaaaagt ttgagagctg agccttcctg cctactgccc
      661 ctgccctgag gagggccctg aggaataaag cttctctctg agctga
//