LOCUS HUMEDG 2757 bp mRNA linear HUM 07-NOV-1994
DEFINITION Human endothelial differentiation protein (edg-1) gene mRNA,
complete cds.
ACCESSION M31210
VERSION M31210.1
KEYWORDS endothelial differentiation protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2757)
AUTHORS Hla,T. and Maciag,T.
TITLE An abundant transcript induced in differentiating human endothelial
cells encodes a polypeptide with structural similarities to
G-protein-coupled receptors
JOURNAL J. Biol. Chem. 265 (16), 9308-9313 (1990)
PUBMED 2160972
COMMENT Original source text: Human umbilical vein endothelial cell, cDNA
to mRNA, clone p4.
Draft entry and computer-readable sequence for [1] kindly submitted
by T.Hla, 11-JAN-1990, for release after publication.
FEATURES Location/Qualifiers
source 1..2757
/db_xref="H-InvDB:HIT000195413"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="22q13"
gene 1..2757
/gene="ECGF1"
misc_feature 246..254
/gene="ECGF1"
/note="consensus KOZAK sequence; putative"
CDS 251..1396
/gene="ECGF1"
/note="endothelial differentiation protein (edg-1)"
/codon_start=1
/protein_id="AAA52336.1"
/db_xref="GDB:G00-127-754"
/translation="MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENS
IKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANL
LLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRL
FLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIV
ILYCRIYSLVRTRSRRLTFRKNISKASRSSENVALLKTVIIVLSVFIACWAPLFILLL
LDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGD
SAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS"
regulatory 2591..2596
/regulatory_class="polyA_signal_sequence"
/gene="ECGF1"
regulatory 2737..2742
/regulatory_class="polyA_signal_sequence"
/gene="ECGF1"
BASE COUNT 671 a 706 c 619 g 761 t
ORIGIN
1 tctaaaggtc gggggcagca gcaagatgcg aagcgagccg tacagatccc gggctctccg
61 aacgcaactt cgccctgctt gagcgaggct gcggtttccg aggccctctc cagccaagga
121 aaagctacac aaaaagcctg gatcactcat cgaaccaccc ctgaagccag tgaaggctct
181 ctcgcctcgc cctctagcgt tcgtctggag tagcgccacc ccggcttcct ggggacacag
241 ggttggcacc atggggccca ccagcgtccc gctggtcaag gcccaccgca gctcggtctc
301 tgactacgtc aactatgata tcatcgtccg gcattacaac tacacgggaa agctgaatat
361 cagcgcggac aaggagaaca gcattaaact gacctcggtg gtgttcattc tcatctgctg
421 ctttatcatc ctggagaaca tctttgtctt gctgaccatt tggaaaacca agaaattcca
481 ccgacccatg tactatttta ttggcaatct ggccctctca gacctgttgg caggagtagc
541 ctacacagct aacctgctct tgtctggggc caccacctac aagctcactc ccgcccagtg
601 gtttctgcgg gaagggagta tgtttgtggc cctgtcagcc tccgtgttca gtctcctcgc
661 catcgccatt gagcgctata tcacaatgct gaaaatgaaa ctccacaacg ggagcaataa
721 cttccgcctc ttcctgctaa tcagcgcctg ctgggtcatc tccctcatcc tgggtggcct
781 gcctatcatg ggctggaact gcatcagtgc gctgtccagc tgctccaccg tgctgccgct
841 ctaccacaag cactatatcc tcttctgcac cacggtcttc actctgcttc tgctctccat
901 cgtcattctg tactgcagaa tctactcctt ggtcaggact cggagccgcc gcctgacgtt
961 ccgcaagaac atttccaagg ccagccgcag ctctgagaat gtggcgctgc tcaagaccgt
1021 aattatcgtc ctgagcgtct tcatcgcctg ctgggcaccg ctcttcatcc tgctcctgct
1081 ggatgtgggc tgcaaggtga agacctgtga catcctcttc agagcggagt acttcctggt
1141 gttagctgtg ctcaactccg gcaccaaccc catcatttac actctgacca acaaggagat
1201 gcgtcgggcc ttcatccgga tcatgtcctg ctgcaagtgc ccgagcggag actctgctgg
1261 caaattcaag cgacccatca tcgccggcat ggaattcagc cgcagcaaat cggacaattc
1321 ctcccacccc cagaaagacg aaggggacaa cccagagacc attatgtctt ctggaaacgt
1381 caactcttct tcctagaact ggaagctgtc cacccaccgg aagcgctctt tacttggtcg
1441 ctggccaccc cagtgtttgg aaaaaaatct ctgggcttcg actgctgcca gggaggagct
1501 gctgcaagcc agagggagga agggggagaa tacgaacagc ctggtggtgt cgggtgttgg
1561 tgggtagagt tagttcctgt gaacaatgca ctgggaaggg tggagatcag gtcccggcct
1621 ggaatatata ttctaccccc ctggagcttt gattttgcac tgagccaaag gtctagcatt
1681 gtcaagctcc taaagggttc atttggcccc tcctcaaaga ctaatgtccc catgtgaaag
1741 cgtctctttg tctggagctt tgaggagatg ttttccttca ctttagtttc aaacccaagt
1801 gagtgtgtgc acttctgctt ctttagggat gccctgtaca tcccacaccc caccctccct
1861 tcccttcata cccctcctca acgttctttt actttatact ttaactacct gagagttatc
1921 agagctgggg ttgtggaatg atcgatcatc tatagcaaat aggctatgtt gagtacgtag
1981 gctgtgggaa gatgaagatg gtttggaggt gtaaaacaat gtccttcgct gaggccaaag
2041 tttccatgta agcgggatcc gttttttgga atttggttga agtcactttg atttctttaa
2101 aaaacatctt ttcaatgaaa tgtgttacca tttcatatcc attgaagccg aaatctgcat
2161 aaggaagccc actttatcta aatgatatta gccaggatcc ttggtgtcct aggagaaaca
2221 gacaagcaaa acaaagtgaa aaccgaatgg attaactttt gcaaaccaag ggagatttct
2281 tagcaaatga gtctaacaaa tatgacatcc gtctttccca cttttgttga tgtttatttc
2341 agaatcttgt gtgattcatt tcaagcaaca acatgttgta ttttgttgtg ttaaaagtac
2401 ttttcttgat ttttgaatgt atttgtttca ggaagaagtc attttatgga tttttctaac
2461 ccgtgttaac ttttctagaa tccaccctct tgtgccctta agcattactt taactggtag
2521 ggaacgccag aacttttaag tccagctatt cattagatag taattgaaga tatgtataaa
2581 tattacaaag aataaaaata tattactgtc tctttagtat ggttttcagt gcaattaaac
2641 cgagagatgt cttgtttttt taaaaagaat agtatttaat aggtttctga cttttgtgga
2701 tcattttgca catagcttta tcaactttta aacattaata aactgatttt tttaaag
//