LOCUS HUMRAG1 6545 bp mRNA linear HUM 08-JAN-1995
DEFINITION Human recombination activating protein (RAG-1) gene, complete cds.
ACCESSION M29474
VERSION M29474.1
KEYWORDS recombination activating protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6545)
AUTHORS Schatz,D.G., Oettinger,M.A. and Baltimore,D.
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 6545)
AUTHORS Schatz,D.G., Oettinger,M.A. and Baltimore,D.
TITLE The V(D)J recombination activating gene, RAG-1
JOURNAL Cell 59 (6), 1035-1048 (1989)
PUBMED 2598259
COMMENT Original source text: Human pre-B cell, line NALM6, cDNA to mRNA,
clone H36.
Draft entry and computer-readable sequence for [2] kindly submitted
by D.G.Schatz 20-OCT-1989.
FEATURES Location/Qualifiers
source 1..6545
/db_xref="H-InvDB:HIT000195321"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Unassigned"
gene 1..6545
/gene="RAG1"
mRNA <1..6545
/gene="RAG1"
/product="RAG1 mRNA"
CDS 113..3244
/gene="RAG1"
/note="recombination activating protein"
/codon_start=1
/protein_id="AAA60248.1"
/db_xref="GDB:G00-120-334"
/translation="MAASFPPTLGLSSAPDEIQHPHIKFSEWKFKLFRVRSFEKTPEE
AQKEKKDSFEGKPSLEQSPAVLDKADGQKPVPTQPLLKAHPKFSKKFHDNEKARGKAI
HQANLRHLCRICGNSFRADEHNRRYPVHGPVDGKTLGLLRKKEKRATSWPDLIAKVFR
IDVKADVDSIHPTEFCHNCWSIMHRKFSSAPCEVYFPRNVTMEWHPHTPSCDICNTAR
RGLKRKSLQPNLQLSKKLKTVLDQARQARQRKRRAQARISSKDVMKKIANCSKIHLST
KLLAVDFPEHFVKSISCQICEHILADPVETNCKHVFCRVCILRCLKVMGSYCPSCRYP
CFPTDLESPVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKG
GRPRQHLLSLTRRAQKHRLRELKLQVKAFADKEEGGDVKSVCMTLFLLALRARNEHRQ
ADELEAIMQGKGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRN
AEKVLLPGYHHFEWQPPLKNVSSSTDVGIIDGLSGLSSSVDDYPVDTIAKRFRYDSAL
VSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKHGSGPVVPEKAVR
FSFTIMKITIAHSSQNVKVFEEAKPNSELCCKPLCLMLADESDHETLTAILSPLIAER
EAMKSSELMLELGGILRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEA
SQNLVFHSITRSHAENLERYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALH
CDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKKMNLKPIMRMNGNF
ARKLMTKETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSF
NSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASEGNESGNKLFR
RFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNALKTSGFTMNPQASLGDPLG
IEDSLESQDSMEF"
BASE COUNT 1848 a 1314 c 1415 g 1968 t
ORIGIN
1 gagagcagag aacacacttt gccttctctt tggtattgag taatatcaac caaattgcag
61 acatctcaac actttggcca ggcagcctgc tgagcaaggt acctcagcca gcatggcagc
121 ctctttccca cccaccttgg gactcagttc tgccccagat gaaattcagc acccacatat
181 taaattttca gaatggaaat ttaagctgtt ccgggtgaga tcctttgaaa agacacctga
241 agaagctcaa aaggaaaaga aggattcctt tgaggggaaa ccctctctgg agcaatctcc
301 agcagtcctg gacaaggctg atggtcagaa gccagtccca actcagccat tgttaaaagc
361 ccaccctaag ttttcaaaga aatttcacga caacgagaaa gcaagaggca aagcgatcca
421 tcaagccaac cttcgacatc tctgccgcat ctgtgggaat tcttttagag ctgatgagca
481 caacaggaga tatccagtcc atggtcctgt ggatggtaaa accctaggcc ttttacgaaa
541 gaaggaaaag agagctactt cctggccgga cctcattgcc aaggttttcc ggatcgatgt
601 gaaggcagat gttgactcga tccaccccac tgagttctgc cataactgct ggagcatcat
661 gcacaggaag tttagcagtg ccccatgtga ggtttacttc ccgaggaacg tgaccatgga
721 gtggcacccc cacacaccat cctgtgacat ctgcaacact gcccgtcggg gactcaagag
781 gaagagtctt cagccaaact tgcagctcag caaaaaactc aaaactgtgc ttgaccaagc
841 aagacaagcc cgtcagcgca agagaagagc tcaggcaagg atcagcagca aggatgtcat
901 gaagaagatc gccaactgca gtaagataca tcttagtacc aagctccttg cagtggactt
961 cccagagcac tttgtgaaat ccatctcctg ccagatctgt gaacacattc tggctgaccc
1021 tgtggagacc aactgtaagc atgtcttttg ccgggtctgc attctcagat gcctcaaagt
1081 catgggcagc tattgtccct cttgccgata tccatgcttc cctactgacc tggagagtcc
1141 agtgaagtcc tttctgagcg tcttgaattc cctgatggtg aaatgtccag caaaagagtg
1201 caatgaggag gtcagtttgg aaaaatataa tcaccacatc tcaagtcaca aggaatcaaa
1261 agagattttt gtgcacatta ataaaggggg ccggccccgc caacatcttc tgtcgctgac
1321 tcggagagct cagaagcacc ggctgaggga gctcaagctg caagtcaaag cctttgctga
1381 caaagaagaa ggtggagatg tgaagtccgt gtgcatgacc ttgttcctgc tggctctgag
1441 ggcgaggaat gagcacaggc aagctgatga gctggaggcc atcatgcagg gaaagggctc
1501 tggcctgcag ccagctgttt gcttggccat ccgtgtcaac accttcctca gctgcagtca
1561 gtaccacaag atgtacagga ctgtgaaagc catcacaggg agacagattt ttcagccttt
1621 gcatgccctt cggaatgctg agaaggtact tctgccaggc taccaccact ttgagtggca
1681 gccacctctg aagaatgtgt cttccagcac tgatgttggc attattgatg ggctgtctgg
1741 actatcatcc tctgtggatg attacccagt ggacaccatt gcaaagaggt tccgctatga
1801 ttcagctttg gtgtctgctt tgatggacat ggaagaagac atcttggaag gcatgagatc
1861 ccaagacctt gatgattacc tgaatggccc cttcactgtg gtggtgaagg agtcttgtga
1921 tggaatggga gacgtgagtg agaagcatgg gagtgggcct gtagttccag aaaaggcagt
1981 ccgtttttca ttcacaatca tgaaaattac tattgcccac agctctcaga atgtgaaagt
2041 atttgaagaa gccaaaccta actctgaact gtgttgcaag ccattgtgcc ttatgctggc
2101 agatgagtct gaccacgaga cgctgactgc catcctgagt cctctcattg ctgagaggga
2161 ggccatgaag agcagtgaat taatgcttga gctgggaggc attctccgga ctttcaagtt
2221 catcttcagg ggcaccggct atgatgaaaa acttgtgcgg gaagtggaag gcctcgaggc
2281 ttctggctca gtctacattt gtactctttg tgatgccacc cgtctggaag cctctcaaaa
2341 tcttgtcttc cactctataa ccagaagcca tgctgagaac ctggaacgtt atgaggtctg
2401 gcgttccaac ccttaccatg agtctgtgga agaactgcgg gatcgggtga aaggggtctc
2461 agctaaacct ttcattgaga cagtcccttc catagatgca ctccactgtg acattggcaa
2521 tgcagctgag ttctacaaga tcttccagct agagataggg gaagtgtata agaatcccaa
2581 tgcttccaaa gaggaaagga aaaggtggca ggccacactg gacaagcatc tccggaagaa
2641 gatgaacctc aaaccaatca tgaggatgaa tggcaacttt gccaggaagc tcatgaccaa
2701 agagactgtg gatgcagttt gtgagttaat tccttccgag gagaggcacg aggctctgag
2761 ggagctgatg gatctttacc tgaagatgaa accagtatgg cgatcatcat gccctgctaa
2821 agagtgccca gaatccctct gccagtacag tttcaattca cagcgttttg ctgagctcct
2881 ttctacgaag ttcaagtata ggtatgaggg aaaaatcacc aattattttc acaaaaccct
2941 ggcccatgtt cctgaaatta ttgagaggga tggctccatt ggggcatggg caagtgaggg
3001 aaatgagtct ggtaacaaac tgtttaggcg cttccggaaa atgaatgcca ggcagtccaa
3061 atgctatgag atggaagatg tcctgaaaca ccactggttg tacacctcca aatacctcca
3121 gaagtttatg aatgctcata atgcattaaa aacctctggg tttaccatga accctcaggc
3181 aagcttaggg gacccattag gcatagagga ctctctggaa agccaagatt caatggaatt
3241 ttaagtaggg caaccactta tgagttggtt tttgcaattg agtttccctc tgggttgcat
3301 tgagggcttc tcctagcacc ctttactgct gtgtatgggg cttcaccatc caagaggtgg
3361 taggttggag taagatgcta cagatgctct caagtcagga atagaaactg atgagctgat
3421 tgcttgaggc ttttagtgag ttccgaaaag caacaggaaa aatcagttat ctgaaagctc
3481 agtaactcag aacaggagta actgcagggg accagagatg agcaaagatc tgtgtgtgtt
3541 ggggagctgt catgtaaatc aaagccaagg ttgtcaaaga acagccagtg aggccagaaa
3601 ttggtcttgt ggttttcatt tttttccccc ttgattgatt atattttgta ttgagatatg
3661 ataagtgcct tctatttcat ttttgaataa ttcttcattt ttataatttt acatatcttg
3721 gcttgctata taagattcaa aagagctttt taaatttttc taataatatc ttacatttgt
3781 acagcatgat gacctttaca aagtgctctc aatgcattta cccattcgtt atataaatat
3841 gttacatcag gacaactttg agaaaatcag tcctttttta tgtttaaatt atgtatctat
3901 tgtaaccttc agagtttagg aggtcatctg ctgtcatgga tttttcaata atgaatttag
3961 aatacacctg ttagctacag ttagttatta aatcttctga taatatatgt ttacttagct
4021 atcagaagcc aagtatgatt ctttattttt actttttcat ttcaagaaat ttagagtttc
4081 caaatttaga gcttctgcat acagtcttaa agccacagag gcttgtaaaa atataggtta
4141 gcttgatgtc taaaaatata tttcatgtct tactgaaaca ttttgccaga ctttctccaa
4201 atgaaacctg aatcaatttt tctaaatcta ggtttcatag agtcctctcc tctgcaatgt
4261 gttattcttt ctataatgat cagtttactt tcagtggatt cagaattgtg tagcaggata
4321 accttgtatt tttccatccg ctaagtttag atggagtcca aacgcagtac agcagaagag
4381 ttaacattta cacagtgctt tttaccactg tggaatgttt tcacactcat ttttccttac
4441 aacaattctg aggagtaggt gttgttatta tctccatttg atgggggttt aatgatttgc
4501 tcaaagtcat ttaggggtaa taaatacttg gcttggaaat ttaacacagt ccttttgtct
4561 ccaaagccct tcttctttcc accacaaatt aatcactatg tttataaggt agtatcagaa
4621 tttttttagg attcacaact aatcactata gcacatgacc ttgggattac atttttatgg
4681 ggcaggggta agcggctttt aaatcatttg tgtgctctgg ctcttttgat agaagaaagc
4741 aacacaaaag ctccaaaggg ccccctaacc ctcttgtggc tccagttatt tggaaactat
4801 gatctgcatc cttaggaatc tgggatttgc cagttgctgg caatgtagag caggcatgga
4861 attttatatg ctagtgagtc ataatgatat gttagtgtta attagttttt cttcctttga
4921 ttttattggc cataattgct actcttcata cacagtatat caaagagctt gataatttag
4981 ttgtcaaaag tgcatcggcg acattatctt taattgtatg tatttggtgc ttcttcaggg
5041 attgaactca gtatctttca ttaaaaaaca cagcagtttt ccttgctttt tatatgcaga
5101 atatcaaagt catttctaat ttagttgtca aaaacatata catattttaa cattagtttt
5161 tttgaaaact cttggttttg tttttttgga aatgagtggg ccactaagcc acactttccc
5221 ttcatcctgc ttaatccttc cagcatgtct ctgcactaat aaacagctaa attcacataa
5281 tcatcctatt tactgaagca tggtcatgct ggtttataga ttttttaccc atttctactc
5341 tttttctcta ttggtggcac tgtaaatact ttccagtatt aaattatcct tttctaacac
5401 tgtaggaact attttgaatg catgtgacta agagcatgat ttatagcaca acctttccaa
5461 taatccctta atcagatcac attttgataa accctgggaa catctggctg caggaatttc
5521 aatatgtaga aacgctgcct atggtttttt gcccttactg ttgagactgc aatatcctag
5581 accctagttt tatactagag ttttattttt agcaatgcct attgcaagtg caattatata
5641 ctccagggaa attcaccaca ctgaatcgag catttgtgtg tgtatgtgtg aagtatatct
5701 gggacttcag aagtgcaatg tatttttctc ctgtgaaacc tgaatctaca agttttctgc
5761 caagccactc aggtgcattg cagggaccag tgataatggc tgatgaaaat tgatgattgg
5821 tcagtgaggt caaaaggagc cttgggatta ataaacatgc actgagaagc aagaggagga
5881 gaaaaagatg tctttttctt ccaggtgaac tggaatttag ttttgcctca gatttttttc
5941 ccacaagata cagaagaaga taaagatttt tttggttgag agtgtgggtc ttgcattaca
6001 tcaaacagag ttcaaattcc acacagataa gaggcaggat atataagcgc cagtggtagt
6061 tgggaggaat aaaccattat ttggatgcag gtggtttttg attgcaaata tgtgtgtgtc
6121 ttcagtgatt gtatgacaga tgatgtattc ttttgatgtt aaaagatttt aagtaagagt
6181 agatacattg tacccatttt acattttctt attttaacta cagtaatcta cataaatata
6241 cctcagaaat catttttggt gattattttt tgttttgtag aattgcactt cagtttattt
6301 tcttacaaat aaccttacat tttgtttaat ggcttccaag agcctttttt tttttgtatt
6361 tcagagaaaa ttcaggtacc aggatgcaat ggatttattt gattcagggg acctgtattt
6421 ccatgtcaaa tgttttcaaa taaaatgaaa tatgagtttc aatacttttt atattttaat
6481 atttccttaa tattatggtt attgtccgcc attttgttgt atattgtaaa taaagtttag
6541 attgt
//