LOCUS HUMATCCD2 1510 bp mRNA linear HUM 27-APR-1993
DEFINITION Human T-cell surface antigen CD2 (T11) mRNA, complete cds.
ACCESSION M14362
VERSION M14362.1
KEYWORDS CD2 surface antigen; T-cell antigen; glycoprotein; immunoglobulin
super gene family.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1510)
AUTHORS Sewell,W.A., Brown,M.H., Dunne,J., Owen,M.J. and Crumpton,M.J.
TITLE Molecular cloning of the human T-lymphocyte surface CD2 (T11)
antigen
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 83 (22), 8718-8722 (1986)
PUBMED 3490670
REMARK Erratum:[Proc Natl Acad Sci U S A 1987 Oct;84(20):7256]
REFERENCE 2 (bases 1006 to 1065)
AUTHORS Sewell,W.A., Brown,M.H., Dunne,J., Owen,M.J. and Crumpton,M.J.
TITLE Correction
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 84, 7256-7256 (1987)
COMMENT Original source text: Human leukemia T-cell line J6, cDNA to mRNA,
clone 141A.
[2] revises [1].
Draft entry and computer-readable copy of the sequence in [1] were
kindly provided by W.A.Sewell, 02-FEB-1987.
FEATURES Location/Qualifiers
source 1..1510
/db_xref="H-InvDB:HIT000194333"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA <1..1509
/product="CD2 mRNA"
CDS 10..1065
/note="T-cell surface antigen CD2 precursor"
/codon_start=1
/protein_id="AAA35571.1"
/translation="MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLD
IPSFQMSDDIDDIKWEKTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQ
DIYKVSIYDTKGKNVLEKIFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQ
DGKHLKLSQRVITHKWTTSLSAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICG
GGSLLMVFVALLVFYITKRKKQRSRRNDEELETRAHRVATEERGRKPHQIPASTPQNP
ATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQ
PKPPHGAAENSLSPSSN"
sig_peptide 10..81
/note="T-cell surface antigen CD2 signal peptide"
mat_peptide 82..1062
/product="T-cell surface antigen CD2"
BASE COUNT 464 a 359 c 329 g 358 t
ORIGIN 410 bp upstream of BglII site; chromosome 1p13.
1 acccctaaga tgagctttcc atgtaaattt gtagccagct tccttctgat tttcaatgtt
61 tcttccaaag gtgcagtctc caaagagatt acgaatgcct tggaaacctg gggtgccttg
121 ggtcaggaca tcaacttgga cattcctagt tttcaaatga gtgatgatat tgacgatata
181 aaatgggaaa aaacttcaga caagaaaaag attgcacaat tcagaaaaga gaaagagact
241 ttcaaggaaa aagatacata taagctattt aaaaatggaa ctctgaaaat taagcatctg
301 aagaccgatg atcaggatat ctacaaggta tcaatatatg atacaaaagg aaaaaatgtg
361 ttggaaaaaa tatttgattt gaagattcaa gagagggtct caaaaccaaa gatctcctgg
421 acttgtatca acacaaccct gacctgtgag gtaatgaatg gaactgaccc cgaattaaac
481 ctgtatcaag atgggaaaca tctaaaactt tctcagaggg tcatcacaca caagtggacc
541 accagcctga gtgcaaaatt caagtgcaca gcagggaaca aagtcagcaa ggaatccagt
601 gtcgagcctg tcagctgtcc agagaaaggt ctggacatct atctcatcat tggcatatgt
661 ggaggaggca gcctcttgat ggtctttgtg gcactgctcg ttttctatat caccaaaagg
721 aaaaaacaga ggagtcggag aaatgatgag gagctggaga caagagccca cagagtagct
781 actgaagaaa ggggccggaa gccccaccaa attccagctt caacccctca gaatccagca
841 acttcccaac atcctcctcc accacctggt catcgttccc aggcacctag tcatcgtccc
901 ccgcctcctg gacaccgtgt tcagcaccag cctcagaaga ggcctcctgc tccgtcgggc
961 acacaagttc accagcagaa aggcccgccc ctccccagac ctcgagttca gccaaaacct
1021 ccccatgggg cagcagaaaa ctcattgtcc ccttcctcta attaaaaaag atagaaactg
1081 tatttttcaa taaaaagcac tgtggatttc tgccctcctg atgtgcatat ccgtacttcc
1141 atgaggtgtt ttctgtgtgc agaacattgt cacctcctga ggctgtgggc cacagccacc
1201 tctgcatctt cgaactcagc catgtggtca acatctggag tttttggtct cctcagagag
1261 ctccatcaca ccagtaagga gaagcaatat aagtgtgatt gcaagaatgg tagaggaccg
1321 agcacagaaa tcttagagat ttcctgtccc ctctcaggtc atgtgtagat gcgataaatc
1381 aagtgattgg tgtgcctggg tctcactaca agcagcctat ctgcttaaga gactctggag
1441 tttcttatgt gccctggtgg acacttgccc accatcctgt gagtaaaagt gaaataaaag
1501 ctttgactag
//