LOCUS BC146857 5698 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens dedicator of cytokinesis 1, mRNA (cDNA clone
MGC:181960 IMAGE:9056785), complete cds.
ACCESSION BC146857
VERSION BC146857.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5698)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5698)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 684 Row: c Column: 23.
FEATURES Location/Qualifiers
source 1..5698
/db_xref="H-InvDB:HIT000503114"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:181960 IMAGE:9056785"
/tissue_type="Brain, cerebral cortex, PCR rescued clones"
/clone_lib="NIH_MGC_289"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: TATTGGAT"
gene 1..5698
/gene="DOCK1"
/gene_synonym="ced5"
/gene_synonym="DOCK180"
/db_xref="GeneID:1793"
/db_xref="HGNC:HGNC:2987"
/db_xref="MIM:601403"
CDS 63..5660
/gene="DOCK1"
/gene_synonym="ced5"
/gene_synonym="DOCK180"
/codon_start=1
/product="dedicator of cytokinesis 1"
/protein_id="AAI46858.1"
/db_xref="GeneID:1793"
/db_xref="HGNC:HGNC:2987"
/db_xref="MIM:601403"
/translation="MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEG
WYRGYTLRKKSKKGIFPASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTI
WRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRIL
DLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFA
ATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLH
NLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGLRRPFGVAVMDVTD
IINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDI
HQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEV
TVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIEDVNRSH
LRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAAT
YLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLK
WRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFI
IGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVNEQLYKAMK
ALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMSDQTVRVKGAAL
KYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIVHSDLFTQHDCR
EILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRKDVGPTQRHVQIIMEKLLRTV
NRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMF
KNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQLWNNYFHLAV
AFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPI
LEMTLIPETELRKATIPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGRGDEQYK
VLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCTVNVL
DFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQRD
GYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKK
QAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQF
PNAEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQR
FEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAI
ETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQ
EHPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEK
EYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFA
LEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEA
VILSETISPLRPQRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSS
LELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPS
KTPPPPPPKTTRKQTSVDSGIVQ"
BASE COUNT 1652 a 1335 c 1426 g 1285 t
ORIGIN
1 atggaaaatg gcggcctaga cgcggagttt cctgcccgac ccgcggcggc tccggcggcg
61 ccatgacgcg ctgggtgccc accaagcgcg aggagaagta cggcgtggct ttttataact
121 atgatgccag aggagcggat gaactttctt tacagatcgg agacactgtg cacatcttag
181 aaacatatga agggtggtac cgaggttaca cgttacgaaa aaagtctaag aagggtatat
241 ttcctgcttc atatattcat cttaaagaag cgatagttga aggaaaaggg caacatgaaa
301 cagtcatccc gggtgacctc cccctcatcc aggaagtcac cacgacactc cgagagtggt
361 ccaccatctg gaggcagctc tacgtgcaag ataacaggga gatgtttcga agtgtgcggc
421 acatgatcta tgaccttatt gaatggcgat cacaaattct ttctggaact ctgcctcagg
481 atgaactcaa agaactgaag aagaaggtca cagccaaaat tgattatgga aacagaattc
541 tagatttgga cctggtggtt agagatgaag atgggaatat tttggatcca gaattaacta
601 gcacgattag tctcttcaga gctcatgaaa tagcttctaa acaagtggag gaaaggttac
661 aagaggaaaa atctcaaaag cagaacatag atattaacag acaagccaag tttgctgcaa
721 ccccttctct ggccttgttt gtgaacctca aaaatgtggt ttgtaaaata ggagaagatg
781 ctgaagtcct catgtctcta tatgaccctg tggagtccaa attcatcagt gagaactacc
841 tggttcgctg gtccagttca ggattaccta aagacataga cagattacat aatttgcgag
901 ccgtgtttac tgacctcgga agcaaagacc tgaaaaggga gaaaatcagt tttgtctgtc
961 agattgttcg cgtgggtcgc atggagctga gggacaacaa caccaggaaa ctgacctcgg
1021 ggttgcggcg accttttgga gtggctgtga tggatgtaac agatataata aatggaaaag
1081 tagatgatga agataagcag catttcattc cctttcagcc ggtggcaggg gagaatgact
1141 tccttcagac tgttataaac aaagtcatcg ctgccaaaga agtcaaccac aaggggcagg
1201 gtttgtgggt aacattgaaa ttacttcctg gagatatcca tcagatccga aaagagtttc
1261 cgcatttagt ggacaggacc acagctgtgg ctcgaaaaac agggtttccg gagataatca
1321 tgcctggtga tgttcgaaat gatatctatg taacattagt tcaaggagat tttgataaag
1381 gaagcaaaac aacagcgaag aacgtggagg tcacggtgtc tgtgtacgat gaggatggga
1441 aacgattaga gcatgtgatt ttcccgggtg ctggtgatga agcgatttca gagtacaaat
1501 ctgtgattta ctaccaagta aagcagccac gctggtttga gactgttaag gtggccattc
1561 ccatcgagga cgttaaccgc agtcaccttc ggtttacctt ccgccacagg tcatcacagg
1621 actctaagga taaatctgag aaaatatttg cactagcatt tgtcaagctg atgagatacg
1681 atggtaccac cctgcgagac ggagagcacg atcttatcgt ctataaggcc gaagcgaaga
1741 agctggaaga tgctgccacg tacttgagtc tgccctccac gaaggcagag ttggaagaaa
1801 agggccactc ggccaccggc aagagcatgc agagccttgg gagctgcacc attagcaagg
1861 actccttcca gatctccacg ctcgtgtgct ccaccaaact gactcagaac gtggaccttc
1921 tggggctctt gaaatggcgc tccaacacca gcctgctgca gcagaacttg aggcagctga
1981 tgaaagtcga tggtggtgaa gtagtgaagt ttcttcagga cacgttggat gccctcttca
2041 acatcatgat ggagaactca gagagtgaga cttttgacac gttagtcttt gatgctctgg
2101 tatttatcat tggactgatt gctgatagaa aatttcagca ttttaatcct gttttggaaa
2161 cttacattaa gaaacacttt agtgcaacgt tagcctacac gaagttgaca aaagtgttga
2221 agaactacgt ggacggtgct gagaagccgg gagtaaatga gcagctgtac aaagccatga
2281 aagcgctaga atccatcttc aagttcatcg tgcgctccag gatcctgttc aatcaactgt
2341 atgaaaacaa gggagaggct gacttcgtgg aatctttgct gcagctcttc aggtccatca
2401 atgacatgat gagcagcatg tcagaccaga ccgtccgggt gaagggggca gcactgaaat
2461 acttaccaac gatcgtcaac gatgtgaaat tggtgtttga tcccaaagag ctcagcaaaa
2521 tgtttactga attcatcctc aatgttccca tgggcttgct gaccatccag aaactctact
2581 gcttgatcga aatcgtccac agtgacctct tcacacagca tgactgcaga gagatcctgc
2641 ttcccatgat gaccgatcag ctcaagtacc atctggagag acaggaggac ctggaggcct
2701 gctgtcagct gctcagccac atcctggagg tgctgtacag gaaggacgtg gggccaaccc
2761 agaggcacgt ccagattatc atggagaaac ttctccggac cgtgaaccga accgtcattt
2821 ccatgggacg ggattctgaa ctcattggaa acttcgtggc ttgcatgaca gctattttac
2881 gacaaatgga agattaccat tatgcccact tgatcaagac ttttgggaaa atgaggactg
2941 atgtggtaga tttcctaatg gaaacattca tcatgtttaa gaacctcatt ggaaagaacg
3001 tttacccctt cgactgggtg atcatgaaca tggtgcaaaa taaagtcttc ctgcgagcaa
3061 ttaatcagta tgcagatatg ctgaacaaaa aatttctgga tcaagccaac tttgagctac
3121 agctgtggaa caactacttt cacctggctg ttgctttcct tactcaagag tccctgcaac
3181 tggagaattt ttcaagtgcc aagagagcca aaatccttaa caagtacgga gatatgagga
3241 gacagattgg ctttgaaatc agagacatgt ggtacaacct tggtcaacac aagataaagt
3301 tcattccaga aatggtgggc ccaatattag aaatgacatt aattcccgag acggagctgc
3361 gcaaagccac catccccatc ttctttgata tgatgcagtg tgaattccat tcgacccgaa
3421 gcttccaaat gtttgaaaat gagatcatca ccaagctgga tcatgaagtc gaaggaggca
3481 gaggagacga acagtacaaa gtgttatttg ataaaatcct tctggaacac tgcaggaagc
3541 acaaatacct cgccaaaaca ggagaaactt ttgtaaaact cgttgtgcgc ttaatggaaa
3601 ggcttttgga ttatagaacc atcatgcacg acgagaacaa agaaaaccgc atgagctgca
3661 ccgtcaatgt gctggatttc tacaaagaaa ttgaaagaga agaaatgtat ataaggtatt
3721 tgtacaagct ctgtgacctg cacaaggagt gtgataacta caccgaagcg gcttacacct
3781 tgcttctcca tgcaaagctt cttaagtggt cggaggatgt gtgtgtggcc cacctcaccc
3841 agcgggacgg gtaccaggcc accacgcagg gacagctgaa ggagcagctc taccaggaaa
3901 tcatccacta cttcgacaaa ggcaagatgt gggaggaggc cattgccttg ggcaaggagc
3961 tagccgagca gtatgagaac gaaatgtttg attatgagca actcagcgaa ttgctgaaaa
4021 aacaggctca gttttatgaa aacatcgtca aagtgatcag gcccaagcct gactattttg
4081 ctgttggcta ctacggacaa gggttcccca cattcctgcg gggaaaagtt ttcatttacc
4141 gagggaaaga gtatgagcgc cgggaagatt ttgaggctcg gctcttaact cagtttccaa
4201 acgccgagaa aatgaagaca acatctccac caggcgacga tattaaaaac tctcctggcc
4261 agtatattca gtgcttcaca gtgaagccca aactcgatct gcctcctaag tttcacaggc
4321 cagtgtcaga gcagattgta agtttttaca gggtgaacga ggtccagcga tttgaatatt
4381 ctcggccaat ccggaaggga gagaaaaacc cagacaatga atttgcgaat atgtggatcg
4441 agagaaccat atatacaact gcatataaat tacctggaat tttaaggtgg tttgaggtca
4501 agtctgtttt catggtggaa atcagccccc tggagaatgc cattgagacc atgcagctga
4561 cgaacgacaa gatcaacagc atggtgcagc agcacctgga tgaccccagc ctgcccatca
4621 acccgctctc catgctcctg aacggcatcg tggacccagc tgtcatgggg ggcttcgcaa
4681 actacgaaaa ggccttcttt acagaccggt acctgcagga gcaccctgag gcccatgaaa
4741 agatcgagaa gctcaaggac ctgattgctt ggcagattcc ttttctggcc gaagggatca
4801 gaatccatgg agacaaagtc acggaggcac tgaggccgtt ccacgagagg atggaggcct
4861 gtttcaaaca gctgaaggaa aaggtggaga aagagtacgg cgtccgaatc atgccctcaa
4921 gtctggatga tagaagaggc agccgccccc ggtccatggt gcggtccttc acgatgcctt
4981 cctcatcccg ccctctgtct gtggcctctg tctcttccct ctcatcggac agcacccctt
5041 ccagaccagg ctccgacggg tttgccctgg agcctctcct gccaaagaaa atgcactcca
5101 ggtcccagga caagctggac aaggatgacc tggagaagga gaagaaggac aagaagaagg
5161 aaaaaaggaa cagcaaacat caagagatat ttgagaaaga atttaaaccc accgacattt
5221 ccctgcagca gtctgaggct gtgatccttt cggaaacgat aagtcccctg cggccccaga
5281 gaccgaagag ccaggtgatg aacgtcattg gaagcgaaag gcgcttctcg gtgtccccct
5341 cgtcaccgtc ctcccagcaa acaccccctc cagttacacc aagagccaag ctcagcttca
5401 gcatgcagtc gagcttggag ctgaacggca tgacgggggc ggacgtggcc gatgtcccac
5461 cccctctgcc tctcaaaggc agcgtggcag attacgggaa tttgatggaa aaccaggact
5521 tgctgggctc gccaacacct ccacctcccc ctccacacca gaggcatctg ccacctccac
5581 tgcccagcaa aactccgcct cctccccctc caaagacaac tcgcaagcag acatcggtgg
5641 actccgggat cgtgcagtga cgtcgcaagg ctctctggaa agagtgtgct gcccctcc
//