LOCUS BC140839 2277 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens kelch-like 4 (Drosophila), mRNA (cDNA clone MGC:176516
IMAGE:9021707), complete cds.
ACCESSION BC140839
VERSION BC140839.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2277)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2277)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAY-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 673 Row: n Column: 9.
FEATURES Location/Qualifiers
source 1..2277
/db_xref="H-InvDB:HIT000501584"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176516 IMAGE:9021707"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_311"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: TTCGCTAC"
gene 1..2277
/gene="KLHL4"
/gene_synonym="DKELCHL"
/gene_synonym="KHL4"
/db_xref="GeneID:56062"
/db_xref="HGNC:HGNC:6355"
/db_xref="MIM:300348"
CDS 52..2214
/gene="KLHL4"
/gene_synonym="DKELCHL"
/gene_synonym="KHL4"
/codon_start=1
/product="kelch-like 4 (Drosophila)"
/protein_id="AAI40840.1"
/db_xref="GeneID:56062"
/db_xref="HGNC:HGNC:6355"
/db_xref="MIM:300348"
/translation="MSVSGKKEFDVKQILRLRWRWFSHPFQGSTNTGSCLQQEGYEHR
GTPVQGRLKSHSRDRNGLKKSNSPVHHNILAPVPGPAPAHQRAVQNLQQHNLIVHFQA
NEDTPKSVPEKNLFKEACEKRAQDLEMMADDNIEDSTARLDTQHSEDMNATRSEEQFH
VINHAEQTLRKMENYLKEKQLCDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEA
KQEEVRMEGVDPNALNSLVQYAYTGVLQLKEDTIESLLAAACLLQLTQVIDVCSNFLI
KQLHPSNCLGIRSFGDAQGCTELLNVAHKYTMEHFIEVIKNQEFLLLPANEISKLLCS
DDINVPDEETIFHALMQWVGHDVQNRQGELGMLLSYIRLPLLPPQLLADLETSSMFTG
DLECQKLLMEAMKYHLLPERRSMMQSPRTKPRKSTVGALYAVGGMDAMKGTTTIEKYD
LRTNSWLHIGTMNGRRLQFGVAVIDNKLYVVGGRDGLKTLNTVECFNPVGKIWTVMPP
MSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPEGRQWNYVASMSTPRSTVGVV
ALNNKLYAIGGRDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATYNGFLYVVGG
HDAPASNHCSRLSDCVERYDPKGDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHT
YLNTVESYDAQRNEWKESMQELLQNFYTTQKLKETLGH"
BASE COUNT 667 a 470 c 545 g 595 t
ORIGIN
1 ggctccgttt cctttctgtg agagaaggct tttgtctttc ctcctgctac gatgtcagtg
61 tctggcaaga aagagtttga tgtgaaacag atcctaaggc tacgctggag gtggtttagt
121 catccttttc aaggttccac caacactgga agctgtcttc agcaggaagg atatgagcat
181 agagggaccc cggttcaggg caggttgaag agccactctc gggacagaaa cggactgaag
241 aaaagcaaca gtcctgtcca ccacaatata ctggcaccag tgccaggacc ggcccctgcc
301 catcagagag ccgttcagaa tttgcagcaa cataatctga tagtacattt tcaagcaaat
361 gaagatactc ctaaatcagt tccagagaag aatttattca aagaagcttg tgagaaacgc
421 gcacaagatt tggagatgat ggctgatgac aatatagaag attctacagc aagattagat
481 acacaacact ctgaagacat gaatgccacc agatctgaag agcagttcca tgttataaac
541 cacgcagagc aaactcttcg taaaatggag aactacttga aagagaaaca actatgtgat
601 gtgctactga ttgcaggaca cctccgcatc ccagcccata ggttggttct cagcgcagtg
661 tctgattatt ttgctgcaat gtttactaat gatgtgcttg aagccaaaca agaagaggtc
721 aggatggaag gagtagatcc aaatgcacta aattccttgg tgcagtatgc ttacacagga
781 gtcctgcaat tgaaagaaga taccattgaa agtttgctgg ctgcagcttg tcttctgcag
841 ctgactcagg tcattgatgt ttgctccaat tttctcataa agcagctcca tccttcaaac
901 tgcttaggga ttcgatcatt tggagatgcc caaggctgta cagaacttct gaacgtggca
961 cacaaataca ctatggaaca cttcattgag gtaataaaaa accaagaatt cctcctgctt
1021 ccagctaatg aaatttcaaa acttctgtgc agtgatgaca ttaatgtgcc tgatgaagag
1081 accatttttc atgctctaat gcagtgggtg ggtcatgatg tgcagaatag gcaaggagaa
1141 ctggggatgc tgctttctta catcagactg ccattactcc caccacagtt actggcagat
1201 cttgaaacca gttccatgtt tactggtgat cttgagtgtc agaagctcct gatggaagct
1261 atgaagtatc atcttttgcc tgagagaaga tccatgatgc aaagccctcg gacaaagcct
1321 agaaaatcaa ctgtgggggc actttatgct gtaggaggca tggatgctat gaaaggtact
1381 actactattg aaaaatatga cctcaggact aacagttggc tacatattgg caccatgaat
1441 ggccgtaggc ttcaatttgg agtcgcagtt attgataata agctctatgt cgtgggagga
1501 agagacggtt taaaaacttt gaatacagtg gaatgtttta atccagttgg caaaatctgg
1561 actgtgatgc ctcccatgtc aacacatcgg cacggcttag gtgtagccac tcttgaagga
1621 ccaatgtatg ctgtaggtgg tcatgatgga tggagctatc taaatactgt agaaagatgg
1681 gaccctgagg gacgacagtg gaattacgta gccagtatgt caactcctag aagcacagtt
1741 ggtgttgttg cattaaacaa caaattatat gctattggtg gacgtgatgg aagttcctgc
1801 ctcaaatcaa tggaatactt tgacccacac actaacaagt ggagtttgtg tgctccaatg
1861 tccaaaagac gtggaggtgt gggagttgcc acatacaatg gattcttata tgttgtaggg
1921 gggcatgatg cccctgcttc caaccattgc tccaggcttt ctgactgtgt ggaacggtat
1981 gatccaaaag gtgattcatg gtcaactgtg gcacctctga gtgttcctcg agatgctgtt
2041 gctgtgtgcc ctcttggaga caaactctac gtggttggag gatatgacgg acatacttat
2101 ttgaacacag ttgagtcata tgatgcacag agaaatgaat ggaaagagag catgcaagaa
2161 cttctacaaa acttctatac cacacagaag ctgaaagaga ctctggggca ctaaattcag
2221 atcctttctc cacacagcaa tgacatttat caatctgact caggtgtggc tgttgcc
//