LOCUS       BC065227                5167 bp    mRNA    linear   HUM 15-JUL-2006
DEFINITION  Homo sapiens signal transducer and activator of transcription 5B,
            mRNA (cDNA clone MGC:74606 IMAGE:5553426), complete cds.
ACCESSION   BC065227
VERSION     BC065227.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5167)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 5167)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2004) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Lou Staudt
            cDNA Library Preparation: Life Technologies, Inc.
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: National Institutes of Health Intramural
            Sequencing Center (NISC),
            Gaithersburg, Maryland;
            Web site: http://www.nisc.nih.gov/
            Contact: nisc_mgc@nhgri.nih.gov
            Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
            Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
            Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
            Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
            Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
            McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
            Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
            Young,A., Zhang,L.-H. and Green,E.D.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRAK Plate: 139 Row: b Column: 4
            This clone was selected for full length sequencing because it
            passed the following selection criteria: matched mRNA gi: 42519913.
FEATURES             Location/Qualifiers
     source          1..5167
                     /db_xref="H-InvDB:HIT000261790"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:74606 IMAGE:5553426"
                     /tissue_type="Lymph, lymphoma"
                     /clone_lib="NIH_MGC_85"
                     /lab_host="DH10B"
                     /note="Vector: pCMV-SPORT6"
     gene            1..5167
                     /gene="STAT5B"
                     /gene_synonym="STAT5"
                     /db_xref="GeneID:6777"
                     /db_xref="HGNC:HGNC:11367"
                     /db_xref="MIM:604260"
     CDS             170..2533
                     /gene="STAT5B"
                     /gene_synonym="STAT5"
                     /codon_start=1
                     /product="signal transducer and activator of transcription
                     5B"
                     /protein_id="AAH65227.1"
                     /db_xref="GI:40807020"
                     /db_xref="GeneID:6777"
                     /db_xref="HGNC:HGNC:11367"
                     /db_xref="MIM:604260"
                     /translation="MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWD
                     SVDLDNPQENIKATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCP
                     MELVRCIRHILYNEQRLVREANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTEN
                     ELKKLQQTQEYFIIQYQESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQRE
                     AQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQ
                     SWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFII
                     EKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDY
                     SGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRSDRRGAESVTEEKFTILFESQFSV
                     GGNELVFQVKTLSLPVVVIVHGSQDNNATATVLWDNAFAEPGRVPFAVPDKVLWPQLC
                     EALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGR
                     NYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEI
                     GGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRLGDLNYLIYVFPDRPKDEVYSKY
                     YTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGGGSATYMDQAPSPAVCPQAHY
                     NMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQWIPHAQS"
BASE COUNT         1304 a         1262 c         1378 g         1223 t
ORIGIN      
        1 ggcgggagga gagtcggcgg ccggagccgt caccccgggc ggggacccag cgcaggcaac
       61 tccgcgcggc ggcccggccg agggagggag cgagcgggcg ggcgggcaag ccagacagct
      121 gggccggagc agccgcgggc gcccgagggg ccgagcgaga ttgtaaacca tggctgtgtg
      181 gatacaagct cagcagctcc aaggagaagc ccttcatcag atgcaagcgt tatatggcca
      241 gcattttccc attgaggtgc ggcattattt atcccagtgg attgaaagcc aagcatggga
      301 ctcagtagat cttgataatc cacaggagaa cattaaggcc acccagctcc tggagggcct
      361 ggtgcaggag ctgcagaaga aggcagagca ccaggtgggg gaagatgggt ttttactgaa
      421 gatcaagctg gggcactatg ccacacagct ccagaacacg tatgaccgct gccccatgga
      481 gctggtccgc tgcatccgcc atatattgta caatgaacag aggttggtcc gagaagccaa
      541 caatggtagc tctccagctg gaagccttgc tgatgccatg tcccagaaac acctccagat
      601 caaccagacg tttgaggagc tgcgactggt cacgcaggac acagagaatg agttaaaaaa
      661 gctgcagcag actcaggagt acttcatcat ccagtaccag gagagcctga ggatccaagc
      721 tcagtttggc ccgctggccc agctgagccc ccaggagcgt ctgagccggg agacggccct
      781 ccagcagaag caggtgtctc tggaggcctg gttgcagcgt gaggcacaga cactgcagca
      841 gtaccgcgtg gagctggccg agaagcacca gaagaccctg cagctgctgc ggaagcagca
      901 gaccatcatc ctggatgacg agctgatcca gtggaagcgg cggcagcagc tggccgggaa
      961 cggcgggccc cccgagggca gcctggacgt gctacagtcc tggtgtgaga agttggccga
     1021 gatcatctgg cagaaccggc agcagatccg cagggctgag cacctctgcc agcagctgcc
     1081 catccccggc ccagtggagg agatgctggc cgaggtcaac gccaccatca cggacattat
     1141 ctcagccctg gtgaccagca cgttcatcat tgagaagcag cctcctcagg tcctgaagac
     1201 ccagaccaag tttgcagcca ctgtgcgcct gctggtgggc gggaagctga acgtgcacat
     1261 gaaccccccc caggtgaagg ccaccatcat cagtgagcag caggccaagt ctctgctcaa
     1321 gaacgagaac acccgcaatg attacagtgg cgagatcttg aacaactgct gcgtcatgga
     1381 gtaccaccaa gccacaggca cccttagtgc ccacttcagg aatatgtccc tgaaacgaat
     1441 taagaggtca gaccgtcgtg gggcagagtc ggtgacagaa gaaaaattta caatcctgtt
     1501 tgaatcccag ttcagtgttg gtggaaatga gctggttttt caagtcaaga ccctgtccct
     1561 gccagtggtg gtgatcgttc atggcagcca ggacaacaat gcgacggcca ctgttctctg
     1621 ggacaatgct tttgcagagc ctggcagggt gccatttgcc gtgcctgaca aagtgctgtg
     1681 gccacagctg tgtgaggcgc tcaacatgaa attcaaggcc gaagtgcaga gcaaccgggg
     1741 cctgaccaag gagaacctcg tgttcctggc gcagaaactg ttcaacaaca gcagcagcca
     1801 cctggaggac tacagtggcc tgtctgtgtc ctggtcccag ttcaacaggg agaatttacc
     1861 aggacggaat tacactttct ggcaatggtt tgacggtgtg atggaagtgt taaaaaaaca
     1921 tctcaagcct cattggaatg atggggccat tttggggttt gtaaacaagc aacaggccca
     1981 tgacctactc attaacaagc cagatgggac cttcctcctg agattcagtg actcagaaat
     2041 tggcggcatc accattgctt ggaagtttga ttctcaggaa agaatgtttt ggaatctgat
     2101 gccttttacc accagagact tctccattcg gtccctagcc gaccgcttgg gagacttgaa
     2161 ttaccttatc tacgtgtttc ctgatcggcc aaaagatgaa gtatactcca aatactacac
     2221 accagttccc tgcgagtctg ctactgctaa agctgttgat ggatacgtga agccacagat
     2281 caagcaagtg gtccctgagt ttgtgaacgc atctgcagat gccgggggcg gcagcgccac
     2341 gtacatggac caggccccct ccccagctgt gtgtccccag gctcactata acatgtaccc
     2401 acagaaccct gactcagtcc ttgacaccga tggggacttc gatctggagg acacaatgga
     2461 cgtagcgcgg cgtgtggagg agctcctggg ccggccaatg gacagtcagt ggatcccgca
     2521 cgcacaatcg tgaccccgcg acctctccat cttcagcttc ttcatcctca ccagaggaat
     2581 cactcttgtg gatgttttaa ttccatgaat cgcttctctt ttgaaacaat actcataatg
     2641 tgaagtgtta atactagttg tgaccttagt gtttctgtgc atggtggcac cagcgaaggg
     2701 agtgcgagta tgtgtttgtg tgtgtgtgtg tgtgtgtgtg tgcgtgtttg cacgttatgg
     2761 tgtttctccc tctcactgtc tgagagttta gttgtagcag aggggccaca gacagaagct
     2821 gtggtggttt ttactttgtg caaaaaggca gtgagtttcg tgaagcctgg aagttggcca
     2881 tgtgtcttaa gagtggctgg actttgacat gtggctgttt gaataagaga aggacaaagg
     2941 gaggagaaag cacatgtgct ccagtgagtc ttcgtcactc tgtctgccaa gcaattgata
     3001 tataaccgtg attgtctctg cttttcttct gaaatgtaga taactgcttt ttgacaaaga
     3061 gagccttccc tctcccccac ccctgtgttc ttgggtagga atgggaaaag gggcaaccta
     3121 caaagattgt tggggcaagg gaagtcacaa gctttcggat gggcggtggc ttttcacaaa
     3181 acatttagct catcttattc tctctttgtc ctctctcccc tcctgcccgc ccgcaccctg
     3241 gaattgccac tcagttcctc tgggtgtgca catatgtttg gagaaataga ggagagaaaa
     3301 gagggccacg taactgagag cttacagtgc caatgccgtt tgtgttctgg ccagagtgga
     3361 gtgcgcagcc ctgactccca ggcgctgaga ttgttgcctg gttacccagg aagctgctgt
     3421 tccggctgcc cagcctttct ctgagccagc ggatgcacag tccgtggcct tcttcaggct
     3481 tattgatgat gctttttgca aatgttgaat catggttctg tttctaagtt ggatcttttt
     3541 tgttttctcc ttgccaccct aatttgacat caaaattctc tcttgtgcat tgggccctgg
     3601 gtcattcaaa cccaggtcac ctcattcccc ttctctgttc acacctaatg tcttgaagag
     3661 taggtagcag cagtgtgggc tgaacctagg ccagcttgct tagcgggtca ccctgctgtg
     3721 aagtcctggc aggtgttggt aatgtgtgga aatgcagtca gcaagtttgc tggggagttt
     3781 gataaaagta taaaacaaaa caaaaaaagc ctcggtataa ttttgttcca cgacttcttc
     3841 tgtagcttta caccagaagg aaggaatggg ctacagcagg tagtggagga agaggggggt
     3901 gagcaggtgt attaaaatag cttacgggta aggcctaaaa ggtcacccct cggccccctc
     3961 tccaaaagaa gggcatgggc acccccagga gaggatggcc ccaaaaacct tatttttata
     4021 catgagagta aataaacata ttttttttac aaaaataact tctgaattta tcagtgtttt
     4081 gccgttaaaa atattcctct atagtaaatt atttattgga agatgacttt tttaaagctg
     4141 ccgtttgcct tggcttggtt tcatacactg atttattttt ctatgccagg cagtagagtc
     4201 tctctgcctc tgaggagcag gctacccgca tcccactcag cccctcccta cccctcaaga
     4261 tttgatgaaa attccaacca tgaggatggg tgcatcgggg aagggtgaga aggagagcct
     4321 gcctgctcag ggatccaggc tcgtagagtc actccctgcc cgtctcccag agatgcttca
     4381 ccagcacctg cctctgagac ctcgctctct gttccagcaa ccctggttgg ggggtcagac
     4441 ttgatacact ttcaggttgg gagtggaccc accccagggc ctgctgagga cagagcagcc
     4501 aggccgtcct ggctcacttt gcagttggca ctgggttggg gaggaagaga gctgatgagt
     4561 gtggcttccc tgagctgggg tttccctgct tgtccagttg tgagctgtcc tcggtgttac
     4621 cgaggctgtg cctagagagt ggagattttt gatgaaaggt gtgctcgctc tctgcgttct
     4681 atcttctctc tcctccttgt tcctgcaaac cacaagataa aggtagtggt gtgtctcgac
     4741 cccatcagcc tctcacccac tcccagacac acacaagtcc tcaaaagttt cagctccgtg
     4801 tgtgagatgt gcaggttttt tctagggggt agggggagac taaaatcgaa tataacttaa
     4861 aatgaaagta tactttttat aatttttctt tttaaaactt ggtgaaatta tttcagatac
     4921 atattttagt gtcaaggcag attagttatt tagccaccaa aaaaaagtat tgtgtacaat
     4981 ttggggcctc aaatttgact ctgcctcaaa aaaaagaaat atatcctatg cagagttaca
     5041 gtcacaaagt tgtgtatttt atgttacaat aaagccttcc tctgaaggga aaaaaaaaaa
     5101 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     5161 aaaaaaa
//