LOCUS BC064987 2501 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens insulin-like growth factor binding protein 3, mRNA
(cDNA clone MGC:71301 IMAGE:4850456), complete cds.
ACCESSION BC064987
VERSION BC064987.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2501)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2501)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2004) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Dr. Mark Watson
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 50 Row: e Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 62243067.
FEATURES Location/Qualifiers
source 1..2501
/db_xref="H-InvDB:HIT000261694"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:71301 IMAGE:4850456"
/tissue_type="Spleen"
/clone_lib="NIH_MGC_113"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2501
/gene="IGFBP3"
/gene_synonym="BP-53"
/gene_synonym="IBP3"
/db_xref="GeneID:3486"
/db_xref="HGNC:HGNC:5472"
/db_xref="MIM:146732"
CDS 117..992
/gene="IGFBP3"
/gene_synonym="BP-53"
/gene_synonym="IBP3"
/codon_start=1
/product="insulin-like growth factor binding protein 3"
/protein_id="AAH64987.1"
/db_xref="GeneID:3486"
/db_xref="HGNC:HGNC:5472"
/db_xref="MIM:146732"
/translation="MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCD
ARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEAR
PLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRV
SDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREME
DTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYT
TKGKEDVHCYSMQSK"
BASE COUNT 617 a 644 c 657 g 583 t
ORIGIN
1 gctgggcgct gaggatcagc cgcttcctgc ctggattcca cagcttcgcg ccgtgtactg
61 tcgccccatc cctgcgcgcc cagcctgcca agcagcgtgc cccggttgca ggcgtcatgc
121 agcgggcgcg acccacgctc tgggccgctg cgctgactct gctggtgctg ctccgcgggc
181 cgccggtggc gcgggctggc gcgagctcgg cgggcttggg tcccgtggtg cgctgcgagc
241 cgtgcgacgc gcgtgcactg gcccagtgcg cgcctccgcc cgccgtgtgc gcggagctgg
301 tgcgcgagcc gggctgcggc tgctgcctga cgtgcgcact gagcgagggc cagccgtgcg
361 gcatctacac cgagcgctgt ggctccggcc ttcgctgcca gccgtcgccc gacgaggcgc
421 gaccgctgca ggcgctgctg gacggccgcg ggctctgcgt caacgctagt gccgtcagcc
481 gcctgcgcgc ctacctgctg ccagcgccgc cagctccagg aaatgctagt gagtcggagg
541 aagaccgcag cgccggcagt gtggagagcc cgtccgtctc cagcacgcac cgggtgtctg
601 atcccaagtt ccaccccctc cattcaaaga taatcatcat caagaaaggg catgctaaag
661 acagccagcg ctacaaagtt gactacgagt ctcagagcac agatacccag aacttctcct
721 ccgagtccaa gcgggagaca gaatatggtc cctgccgtag agaaatggaa gacacactga
781 atcacctgaa gttcctcaat gtgctgagtc ccaggggtgt acacattccc aactgtgaca
841 agaagggatt ttataagaaa aagcagtgtc gcccttccaa aggcaggaag cggggcttct
901 gctggtgtgt ggataagtat gggcagcctc tcccaggcta caccaccaag gggaaggagg
961 acgtgcactg ctacagcatg cagagcaagt agacgcctgc cgcaaggtta atgtggagct
1021 caaatatgcc ttattttgca caaaagactg ccaaggacat gaccagcagc tggctacagc
1081 ctcgatttat atttctgttt gtggtgaact gatttttttt aaaccaaagt ttagaaagag
1141 gtttttgaaa tgcctatggt ttctttgaat ggtaaacttg agcatctttt cactttccag
1201 tagtcagcaa agagcagttt gaattttctt gtcgcttcct atcaaaatat tcagagactc
1261 gagcacagca cccagacttc atgcgcccgt ggaatgctca ccacatgttg gtcgaagcgg
1321 ccgaccactg actttgtgac ttaggcggct gtgttgccta tgtagagaac acgcttcacc
1381 cccactcccc gtacagtgcg cacaggcttt atcgagaata ggaaaacctt taaaccccgg
1441 tcatccggac atcccaacgc atgctcctgg agctcacagc cttctgtggt gtcatttctg
1501 aaacaagggc gtggatccct caaccaagaa gaatgtttat gtcttcaagt gacctgtact
1561 gcttggggac tattggagaa aataaggtgg agtcctactt gtttaaaaaa tatgtatcta
1621 agaatgttct agggcattct gggaacctat aaaggcaggt atttcgggcc ctcctcttca
1681 ggaatcttcc tgaagacatg gcccagtcga aggcccagga tggcttttgc tgcggccccg
1741 tggggtagga gggacagaga gacagggaga gtcagcctcc acattcagag gcatcacaag
1801 taatggcaca attcttcgga tgactgcaga aaatagtgtt ttgtagttca acaactcaag
1861 acgaagctta tttctgagga taagctcttt aaaggcaaag ctttattttc atctctcatc
1921 ttttgtcctc cttagcacaa tgtaaaaaag aatagtaata tcagaacagg aaggaggaat
1981 ggcttgctgg ggagcccatc caggacactg ggagcacata gagattcacc catgtttgtt
2041 gaacttagag tcattctcat gcttttcttt ataattcaca catatatgca gagaagatat
2101 gttcttgtta acattgtata caacatagcc ccaaatatag taagatctat actagataat
2161 cctagatgaa atgttagaga tgctatatga tacaactgtg gccatgactg aggaaaggag
2221 ctcacgccca gagactgggc tgctctcccg gaggccaaac ccaagaaggt ctggcaaagt
2281 caggctcagg gagactctgc cctgctgcag acctcggtgt ggacacacgc tgcatagagc
2341 tctccttgaa aacagagggg tctcaagaca ttctgcctac ctattagctt ttctttattt
2401 ttttaacttt ttggggggaa aagtattttt gagaagtttg tcttgcaatg tatttataaa
2461 tagtaaataa agtttttacc attaaaaaaa aaaaaaaaaa a
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