LOCUS BC058841 914 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens ADAM metallopeptidase with thrombospondin type 1
motif, 12, mRNA (cDNA clone IMAGE:6701691), complete cds.
ACCESSION BC058841
VERSION BC058841.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 914)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 914)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-SEP-2003) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: NCI
cDNA Library Preparation: Michael Brownstein / Ted Usdin
Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 48 Row: m Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 51558723
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..914
/db_xref="H-InvDB:HIT000259878"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:6701691"
/tissue_type="Pooled, 40 cell lines"
/clone_lib="NIH_MGC_128"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..914
/gene="ADAMTS12"
/gene_synonym="PRO4389"
/db_xref="GeneID:81792"
/db_xref="HGNC:HGNC:14605"
/db_xref="MIM:606184"
CDS 168..857
/gene="ADAMTS12"
/gene_synonym="PRO4389"
/codon_start=1
/product="ADAMTS12 protein"
/protein_id="AAH58841.1"
/db_xref="GeneID:81792"
/db_xref="HGNC:HGNC:14605"
/db_xref="MIM:606184"
/translation="MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEH
FIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDWVYYRISHEEKDL
FFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSAC
HGLTGFFQLPHGDFFIEPVKKHPLVEGGYHPHIVYRRQKVPETKEPTCGLKGIVTHMS
SWVEESVLFFW"
BASE COUNT 231 a 221 c 231 g 231 t
ORIGIN
1 gggggcttaa aaaagcacag ggagatcgcg ggcagctttg cagtcgctgc cttctcgcgc
61 ctgaccatgc acccctgcat cttcctgctg ggccacaggc gagcgcttta tttctggagc
121 tgagggctaa aacttttttg acttttcttc tcctcaacat ctgaatcatg ccatgtgccc
181 agaggagctg gcttgcaaac ctttccgtgg tggctcagct ccttaacttt ggggcgcttt
241 gctatgggag acagcctcag ccaggcccgg ttcgcttccc ggacaggagg caagagcatt
301 ttatcaaggg cctgccagaa taccacgtgg tgggtccagt ccgagtagat gccagtgggc
361 attttttgtc atatggcttg cactatccca tcacgagcag caggaggaag agagatttgg
421 atggctcaga ggactgggtg tactacagaa tttctcacga ggagaaggac ctgtttttta
481 acttgacggt caatcaagga tttctttcca atagctacat catggagaag agatatggga
541 acctctccca tgttaagatg atggcttcct cagcccccct ctgccatctc agtggcacgg
601 ttctacagca gggcaccaga gttgggacgg cagccctcag tgcctgccat ggactgactg
661 gatttttcca actaccacat ggagactttt tcattgaacc cgtgaagaag catccactgg
721 ttgagggagg gtaccacccg cacatcgttt acaggaggca gaaagttcca gaaaccaagg
781 agccaacctg tggattaaag ggtattgtga ctcacatgtc ctcctgggtt gaagaatctg
841 ttttgttctt ttggtagttt tattaaaaca tgacctattc ttactcaaaa ataaaaaaaa
901 aaaaaaaaaa aaaa
//