LOCUS BC028057 3030 bp mRNA linear HUM 26-JUN-2007
DEFINITION Homo sapiens DENN/MADD domain containing 4A, mRNA (cDNA clone
IMAGE:5139692), partial cds.
ACCESSION BC028057
VERSION BC028057.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3030)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3030)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (08-APR-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 62 Row: c Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 39930312.
FEATURES Location/Qualifiers
source 1..3030
/db_xref="H-InvDB:HIT000091470"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:5139692"
/tissue_type="Cervix, carcinoma"
/clone_lib="NIH_MGC_12"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..>3030
/gene="DENND4A"
/gene_synonym="IRLB"
/db_xref="GeneID:10260"
/db_xref="HGNC:HGNC:24321"
/db_xref="MIM:600382"
CDS 231..>3030
/gene="DENND4A"
/gene_synonym="IRLB"
/codon_start=1
/product="DENND4A protein"
/protein_id="AAH28057.1"
/db_xref="GeneID:10260"
/db_xref="HGNC:HGNC:24321"
/db_xref="MIM:600382"
/translation="MIEDKGPRVADYFVVAGLTDVSKPLEEEIHFNDACHKVAKPKEP
ITDVSVIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTD
LGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTD
ICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQ
EDYESFSLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFY
EPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLYR
YSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGK
FSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVP
LCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKIL
PKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAF
LFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQM
FIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGEVRLIELDESFKSEHTVFVTPPEI
PHLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTK
QEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALKTAYDVLK
KMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVL
ESTWPSRSRSGYFLWTKVRNVVLGVTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKD
EVRRGDTSTEDIQEEKKKK"
BASE COUNT 907 a 626 c 613 g 884 t
ORIGIN
1 ccacgcgtcc ggctaagcgg gctcagagcg ccgcggcatt cagcccctcg tgttccgcta
61 ccgcgcgtgc gggattccgg cgccgctctc cgagctcgat ccgctgctcg cacgggagcc
121 agctgggtgt tatttctcaa actctgaggc tgcggagttc acacattgaa atctgtcatc
181 tttttcagag agaaactttc ggtaatgtat gtaaccttct gtaatggaag atgattgaag
241 acaaggggcc tcgtgttgct gactactttg ttgtagcagg attaactgat gtttcaaagc
301 ctctagaaga agaaattcac ttcaatgatg cttgtcataa agtagctaaa ccaaaagaac
361 ctattacaga tgtttcagtt attatcaaat ctcttgggga ggaagtccca caggattata
421 tctgtattga tgttacccca actggattgt cagctgatct taataatgga agtcttgtgg
481 ggccacagat ttacctttgc tatagaagag gaagagataa gcctccactt acagatctgg
541 gggttttata tgactggaaa gaaagattga aacagggttg tgaaattatt cagagtactc
601 cctatgggcg ccccgcaaat attagtggga gtacctcatc acaaagaatt tatatcactt
661 accgaagagc ctctgaaaac atgactcaga atacgttggc tgtcactgac atatgtatta
721 ttatacccag taaaggagaa agcccaccac acacgttctg caaagtcgac aagaatctca
781 ataacagtat gtggggatca gcagtatact tgtgttataa aaaatcggtg gcaaagacga
841 acactgtatc ttacaaagct ggcctaattt gtagatatcc tcaagaagat tatgagtcat
901 tctcactacc ggaatctgtt cctctatttt gtttaccaat gggtgcaacc attgaatgtt
961 ggccatcaaa tagcaaatac cctctgcctg tattttctac ttttgtttta actggagcct
1021 cagctgaaaa ggtttatggt gctgctattc agttttatga accatactct gaggagaatc
1081 tcacagaaaa gcagagactt cttttgggtt taacatcagc agatgggaag tctgatagtt
1141 ccaaaacaat tcatactaac aaatgcatct gtcttctttc tcactggcct ttttttgatg
1201 cattcaggaa gtttctgact tttctgtatc gttattccat ctctgggcct catgtccttc
1261 caattgagaa gcatatttct cattttatgc ataaagttcc ttttccatct cctcagagac
1321 cacggatttt agttcagtta tcaccacatg ataatctgat tctcagtcag cctgtgtctt
1381 cacctcttcc actaagtggt ggcaagtttt caacactact gcagaattta ggccctgaaa
1441 atgctgtgac actactggtg tttgcagtaa cagaacataa aattcttatc cattccctac
1501 ggccatccgt gcttactagt gtgacagaag cattagtgtc tatgattttc cctttccact
1561 ggccatgccc gtatgttcct ctctgcccac tggctttagc agatgtcttg agtgcaccat
1621 gtccattcat agtagggatt gattcaagat actttgatct ctatgatcct ccaccagatg
1681 tcagttgtgt tgatgtagat accaacacta tttctcaaat tggtgacaag aaaaatgtag
1741 cctggaagat acttccaaag aagccatgta aaaatctgat gaacacactg aataatttgc
1801 atcagcaatt ggcaaaattg cagcagagac cgagagatga tggactcatg gatttagcaa
1861 taaatgacta tgattttaat tctggaaaga ggttgcacat gatagatttg gaaatccaag
1921 aggcattttt gtttttcatg gcctctattt taaaaggtta cagatcatac ttaaggccaa
1981 taacacaagc cccatctgag acagccacag atgcagcctc tctctttgcc ctacaagctt
2041 tcttaagaag ccgggaccgg tcacatcaaa aattctataa catgatgacc aaaacacaaa
2101 tgtttattcg cttcattgaa gaatgttctt ttgttagtga caaagatgca agcctggcat
2161 tttttgatga ttgtgtagat aaagtggata tggacaagag cggtgaagta cgacttatag
2221 aactggatga atctttcaaa agtgaacaca ctgtttttgt aacaccacct gagatccccc
2281 acctacccaa tggtgaagaa ccccctttac agtacagcta taatggattt ccagttctta
2341 ggaacaattt atttgaaaga cctgaaggat ttctacaagc aaagaagaac aaattgcctt
2401 caaaatcaag tagtcctaat agccctttgc ccatgttcag aagaacaaaa caggaaatta
2461 aatcagccca taaaattgca aagaggtact cttccatccc tcagatgtgg tctaggtgtc
2521 tactgcgcca ctgttatgga ctgtggttta tttgtctccc agcttatgtg aaagtctgtc
2581 attcaaaagt cagggctctg aaaacagcat atgatgtgct taaaaaaatg cagtcaaaga
2641 agatggatcc acctgatgag gtatgctacc gcattcttat gcaactctgt ggacaatatg
2701 atcagccagt gcttgcagtt cgagtgcttt ttgaaatgca gaaagctggt attgacccca
2761 atgccattac ttatggttat tataataagg ctgttttgga aagtacctgg ccttcaagaa
2821 gtcgtagtgg ctattttctt tggacaaaag taagaaatgt tgttttagga gtaacacagt
2881 tcaaaagagc tttaaagaag catgcacact tatcacaaac aactctctca ggtggccagt
2941 ctgatcttgg atataattca ttatctaaag atgaagttag aagaggggat acatctactg
3001 aagacattca agaagaaaaa aaaaaaaaaa
//