LOCUS BC022049 1820 bp mRNA linear HUM 03-JAN-2005
DEFINITION Homo sapiens phosphoinositide-3-kinase, catalytic, beta
polypeptide, mRNA (cDNA clone IMAGE:4291567), partial cds.
ACCESSION BC022049
VERSION BC022049.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1820)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1820)
AUTHORS Director MGC Project.
TITLE Direct Submission
JOURNAL Submitted (22-JAN-2002) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Sep 16, 2003 this sequence version replaced BC022049.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: CLONTECH
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 38 Row: b Column: 20.
FEATURES Location/Qualifiers
source 1..1820
/db_xref="H-InvDB:HIT000090512"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4291567"
/tissue_type="Skeletal Muscle"
/clone_lib="NIH_MGC_81"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene <1..1820
/gene="PIK3CB"
/gene_synonym="p110-BETA"
/gene_synonym="PI3K"
/gene_synonym="PI3Kbeta"
/gene_synonym="PIK3C1"
/db_xref="GeneID:5291"
/db_xref="MIM:602925"
CDS <1..420
/gene="PIK3CB"
/gene_synonym="p110-BETA"
/gene_synonym="PI3K"
/gene_synonym="PI3Kbeta"
/gene_synonym="PIK3C1"
/codon_start=1
/product="PIK3CB protein"
/protein_id="AAH22049.1"
/db_xref="GeneID:5291"
/db_xref="MIM:602925"
/translation="QLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGN
TEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKS
EEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS"
BASE COUNT 574 a 311 c 333 g 602 t
ORIGIN
1 cagctcttcc acattgactt tggacatatt cttggaaatt tcaaatctaa gtttggcatt
61 aaaagggagc gagtgccttt tattcttacc tatgatttca tccatgtcat tcaacaagga
121 aaaacaggaa atacagaaaa gtttggccgg ttccgccagt gttgtgagga tgcatatctg
181 attttacgac ggcatgggaa tctcttcatc actctctttg cgctgatgtt gactgcaggg
241 cttcctgaac tcacatcagt caaagatata cagtatctta aggactctct tgcattaggg
301 aagagtgaag aagaagcact caaacagttt aagcaaaaat ttgatgaggc gctcagggaa
361 agctggacta ctaaagtgaa ctggatggcc cacacagttc ggaaagacta cagatcttaa
421 cgatcagcct tcgctcctaa tgtatttgtt ggtttcattt cattttcatt ttgcacttgc
481 actaaattga acatgaccct gttagagatg ttataaaggg aatgaaatcc tggaactcag
541 agttaaatta agaacaaggc atcccacaga acctaatctg aacaatcccc gatgattccc
601 tctgcttttt gaatgcttcc aagacttatc atgaaaactg tcaatggata atcatttcct
661 gctgactttg cacgccaagg aatgctacta gggattgttt ccgtttttgt ttgttttttc
721 taatatttgg tacttcccag aatggtgtaa atacttcttt tcaatgttgt gaccaagtat
781 tgtcactcag ccaacaactt ttccacacct gggggttggt ggctgttctt actgtccaaa
841 tgaagctaaa aagaaaggca tctttcttcc cttttaaaat tgtgtaaact gcaaattata
901 atataatttg aatttatgat tattttccag aagaaatctt gtaaacctgt ggatactcat
961 taattctttt gttaatattt atttccatga tagcatcatt ccagccagac ttgctgaaaa
1021 tctactggtg aggcaaatat aatatatata aatatgctac atatatattt ataaaatttc
1081 tagtgggagt tctatataaa tgtttctttg gtattcttca gcctgtgatt taaagtttta
1141 caaaaagcag agctttttcc taagttactt ttcagttagg taactgtgtg atccagttct
1201 tccagctgct tctataatga ggcacatatt aatacagttt ttatatggta tctatgaaag
1261 agttcacttc atagagaata atacttgagc aaatgtatcc aagaaagcaa gcaaatgaaa
1321 agaaacctat ttatggaata aactccagat ctgaaattca gtattttaga aaaatgccag
1381 ctcttcttac tgtatttatt aaaacttgta ataatgtgat ttttttcaag gatattagtt
1441 caaattgaaa tggtttcacg ccacacggaa atctttaagt tatttgttga ggtaccatat
1501 atttagggtg ctaggggcaa gtaatgttaa tatgtgcaat aggaactact ggtttgaatg
1561 tgtaaatggg tgatctctct gagtcctggc aacatccagc aaaactactg cttattctcc
1621 aaagaatatt gggagctctc aatcctcggt gatatgggaa agagaactga gtatttgccc
1681 tatgactgag ctttctatag gaattttatt aaagaatgtt taattttgtt gtccttctta
1741 atgttctcag tcaaataaat gagtgagctg gtttcggctg ctcttggaca aaaaaaaaaa
1801 aaaaaaaaaa aaaaaaaaaa
//