LOCUS BC018128 4086 bp mRNA linear HUM 07-AUG-2008
DEFINITION Homo sapiens fibroblast growth factor receptor 1, mRNA (cDNA clone
MGC:9218 IMAGE:3896359), complete cds.
ACCESSION BC018128
VERSION BC018128.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4086)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4086)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 14 Row: i Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13186250.
FEATURES Location/Qualifiers
source 1..4086
/db_xref="H-InvDB:HIT000050696"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9218 IMAGE:3896359"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_70"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..4086
/gene="FGFR1"
/gene_synonym="BFGFR"
/gene_synonym="CD331"
/gene_synonym="CEK"
/gene_synonym="FGFBR"
/gene_synonym="FLG"
/gene_synonym="HBGFR"
/gene_synonym="N-SAM"
/db_xref="GeneID:2260"
/db_xref="HGNC:HGNC:3688"
/db_xref="MIM:136350"
CDS 707..3169
/gene="FGFR1"
/gene_synonym="BFGFR"
/gene_synonym="CD331"
/gene_synonym="CEK"
/gene_synonym="FGFBR"
/gene_synonym="FLG"
/gene_synonym="HBGFR"
/gene_synonym="N-SAM"
/codon_start=1
/product="fibroblast growth factor receptor 1"
/protein_id="AAH18128.1"
/db_xref="GeneID:2260"
/db_xref="HGNC:HGNC:3688"
/db_xref="MIM:136350"
/translation="MWSWKCLLFWAVLVTATLCTARPSPTLPEQAQPWGAPVEVESFL
VHPGDLLQLRCRLRDDVQSINWLRDGVQLAESNRTRITGEEVEVQDSVPADSGLYACV
TSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKME
KKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATGSIIMDSV
VPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCK
VYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDA
GEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSV
IVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSS
GTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTK
VAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGN
LREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAA
RNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVW
SFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPS
QRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEP
LPEEPCLPRHPAQLANGGLKRR"
BASE COUNT 895 a 1212 c 1181 g 798 t
ORIGIN
1 gcgtcctcgg cggcgggcgg cagctagcgg gagccgggac gccggtgcag ccgcagcgcg
61 cggaggaacc cgggtgtgcc gggagctggg cggccacgtc cggacgggac cgagacccct
121 cgtagcgcat tgcggcgacc tcgccttccc cggccgcgag cgcgccgctg cttgaaaagc
181 cgcggaaccc aaggactttt ctccggtccg agctcggggc gccccgcagg gcgcacggta
241 cccgtgctgc agtcgggcac gccgcggcgc cggggcctcc gcagggcgat ggagcccggt
301 ctgcaaggaa agtgaggcgc cgccgctgcg ttctggagga ggggggcaca aggtctggag
361 accccgggtg gcggacggga gccctccccc cgccccgcct ccggggcacc agctccggct
421 ccattgttcc cgcccgggct ggaggcgccg agcaccgagc gccgccggga gtcgagcgcc
481 ggccgcggag ctcttgcgac cccgccagga cccgaacaga gcccgggggc ggcgggccgg
541 agccggggac gcgggcacac gcccgctcgc acaagccacg gcggactctc ccgaggcgga
601 acctccacgc cgagcgaggg tcagtttgaa aaggaggatc gagctcactg tggagtatcc
661 atggagatgt ggagccttgt caccaacctc taactgcaga actgggatgt ggagctggaa
721 gtgcctcctc ttctgggctg tgctggtcac agccacactc tgcaccgcta ggccgtcccc
781 gaccttgcct gaacaagccc agccctgggg agcccctgtg gaagtggagt ccttcctggt
841 ccaccccggt gacctgctgc agcttcgctg tcggctgcgg gacgatgtgc agagcatcaa
901 ctggctgcgg gacggggtgc agctggcgga aagcaaccgc acccgcatca caggggagga
961 ggtggaggtg caggactccg tgcccgcaga ctccggcctc tatgcttgcg taaccagcag
1021 cccctcgggc agtgacacca cctacttctc cgtcaatgtt tcagatgctc tcccctcctc
1081 ggaggatgat gatgatgatg atgactcctc ttcagaggag aaagaaacag ataacaccaa
1141 accaaacccc gtagctccat attggacatc cccagaaaag atggaaaaga aattgcatgc
1201 agtgccggct gccaagacag tgaagttcaa atgcccttcc agtgggaccc caaaccccac
1261 actgcgctgg ttgaaaaatg gcaaagaatt caaacctgac cacagaattg gaggctacaa
1321 ggtccgttat gccaccggga gcatcataat ggactctgtg gtgccctctg acaagggcaa
1381 ctacacctgc attgtggaga atgagtacgg cagcatcaac cacacatacc agctggatgt
1441 cgtggagcgg tcccctcacc ggcccatcct gcaagcaggg ttgcccgcca acaaaacagt
1501 ggccctgggt agcaacgtgg agttcatgtg taaggtgtac agtgacccgc agccgcacat
1561 ccagtggcta aagcacatcg aggtgaatgg gagcaagatt ggcccagaca acctgcctta
1621 tgtccagatc ttgaagactg ctggagttaa taccaccgac aaagagatgg aggtgcttca
1681 cttaagaaat gtctcctttg aggacgcagg ggagtatacg tgcttggcgg gtaactctat
1741 cggactctcc catcactctg catggttgac cgttctggaa gccctggaag agaggccggc
1801 agtgatgacc tcgcccctgt acctggagat catcatctat tgcacagggg ccttcctcat
1861 ctcctgcatg gtggggtcgg tcatcgtcta caagatgaag agtggtacca agaagagtga
1921 cttccacagc cagatggctg tgcacaagct ggccaagagc atccctctgc gcagacaggt
1981 aacagtgtct gctgactcca gtgcatccat gaactctggg gttcttctgg ttcggccatc
2041 acggctctcc tccagtggga ctcccatgct agcaggggtc tctgagtatg agcttcccga
2101 agaccctcgc tgggagctgc ctcgggacag actggtctta ggcaaacccc tgggagaggg
2161 ctgctttggg caggtggtgt tggcagaggc tatcgggctg gacaaggaca aacccaaccg
2221 tgtgaccaaa gtggctgtga agatgttgaa gtcggacgca acagagaaag acttgtcaga
2281 cctgatctca gaaatggaga tgatgaagat gatcgggaag cataagaata tcatcaacct
2341 gctgggggcc tgcacgcagg atggtccctt gtatgtcatc gtggagtatg cctccaaggg
2401 caacctgcgg gagtacctgc aggcccggag gcccccaggg ctggaatact gctacaaccc
2461 cagccacaac ccagaggagc agctctcctc caaggacctg gtgtcctgcg cctaccaggt
2521 ggcccgaggc atggagtatc tggcctccaa gaagtgcata caccgagacc tggcagccag
2581 gaatgtcctg gtgacagagg acaatgtgat gaagatagca gactttggcc tcgcacggga
2641 cattcaccac atcgactact ataaaaagac aaccaacggc cgactgcctg tgaagtggat
2701 ggcacccgag gcattatttg accggatcta cacccaccag agtgatgtgt ggtctttcgg
2761 ggtgctcctg tgggagatct tcactctggg cggctcccca taccccggtg tgcctgtgga
2821 ggaacttttc aagctgctga aggagggtca ccgcatggac aagcccagta actgcaccaa
2881 cgagctgtac atgatgatgc gggactgctg gcatgcagtg ccctcacaga gacccacctt
2941 caagcagctg gtggaagacc tggaccgcat cgtggccttg acctccaacc aggagtacct
3001 ggacctgtcc atgcccctgg accagtactc ccccagcttt cccgacaccc ggagctctac
3061 gtgctcctca ggggaggatt ccgtcttctc tcatgagccg ctgcccgagg agccctgcct
3121 gccccgacac ccagcccagc ttgccaatgg cggactcaaa cgccgctgac tgccacccac
3181 acgccctccc cagactccac cgtcagctgt aaccctcacc cacagcccct gctgggccca
3241 ccacctgtcc gtccctgtcc cctttcctgc tggcaggagc cggctgccta ccaggggcct
3301 tcctgtgtgg cctgccttca ccccactcag ctcacctctc cctccacctc ctctccacct
3361 gctggtgaga ggtgcaaaga ggcagatctt tgctgccagc cacttcatcc cctcccagat
3421 gttggaccaa cacccctccc tgccaccagg cactgcctgg agggcaggga gtgggagcca
3481 atgaacaggc atgcaagtga gagcttcctg agctttctcc tgtcggtttg gtctgttttg
3541 ccttcaccca taagcccctc gcactctggt ggcaggtgcc ttgtcctcag ggctacagca
3601 gtagggaggt cagtgcttcg tgcctcgatt gaaggtgacc tctgccccag ataggtggtg
3661 ccagtggctt attaattccg atactagttt gctttgctga ccaaatgcct ggtaccagag
3721 gatggtgagg cgaaggccag gttgggggca gtgttgtggc cctggggccc agccccaaac
3781 tgggggctct gtatatagct atgaagaaaa cacaaagtgt ataaatctga gtatatattt
3841 acatgtcttt ttaaaagggt cgttaccaga gatttaccca tcgggtaaga tgctcctggt
3901 ggctgggagg catcagttgc tatatattaa aaacaaaaaa gaaaaaaaag gaaaatgttt
3961 ttaaaaaggt catatatttt ttgctacttt tgctgtttta tttttttaaa ttatgttcta
4021 aacctatttt cagtttaggt ccctcaataa aaattgctgc tgcttcattt aaaaaaaaaa
4081 aaaaaa
//