LOCUS BC017183 1849 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens zyxin, mRNA (cDNA clone IMAGE:3347542), partial cds.
ACCESSION BC017183
VERSION BC017183.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1849)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1849)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (05-NOV-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC017183.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: h Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..1849
/db_xref="H-InvDB:HIT000089207"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3347542"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..1849
/gene="ZYX"
/db_xref="GeneID:7791"
/db_xref="MIM:602002"
CDS <1..1403
/gene="ZYX"
/codon_start=3
/product="ZYX protein"
/protein_id="AAH17183.2"
/db_xref="GeneID:7791"
/db_xref="MIM:602002"
/translation="RPLSSPSLLLPCVPPEEEGGPEAPIPPPPQPREKVSSIDLEIDS
LSSLLDDMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQP
LPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKF
SPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPR
VQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNE
LCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDT
LEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHK
QYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPL
DGHVLCRKCHTARAQT"
misc_feature 834..995
/gene="ZYX"
/note="LIM; Region: LIM domain. This family represents two
copies of the LIM structural domain"
/db_xref="CDD:pfam00412"
misc_feature 1011..1169
/gene="ZYX"
/note="LIM; Region: Zinc-binding domain present in Lin-11,
Isl-1, Mec-3. Zinc-binding domain family. Some LIM domains
bind protein partners via tyrosine-containing motifs. LIM
domains are found in many key regulators of developmental
pathways"
/db_xref="CDD:smart00132"
misc_feature 1191..1379
/gene="ZYX"
/note="LIM; Region: Zinc-binding domain present in Lin-11,
Isl-1, Mec-3. Zinc-binding domain family. Some LIM domains
bind protein partners via tyrosine-containing motifs. LIM
domains are found in many key regulators of developmental
pathways"
/db_xref="CDD:smart00132"
BASE COUNT 373 a 663 c 468 g 345 t
ORIGIN
1 cccgccccct ctcttctccc tccctcctcc ttccgtgtgt ccctccggag gaggagggag
61 ggcctgaggc ccccataccg cccccaccac agcccaggga gaaggtgagc agtattgatt
121 tggagatcga ctctctgtcc tcactgctgg atgacatgac caagaatgat cctttcaaag
181 cccgggtgtc atctggatat gtgcccccac cagtggccac tccattcagt tccaagtcca
241 gtaccaagcc tgcagccggg ggcacagcac ccctgcctcc ttggaagtcc ccttccagct
301 cccagcctct gccccaggtt ccggctccgg ctcagagcca gacacagttc catgttcagc
361 cccagcccca gcccaagcct caggtccaac tccatgtcca gtcccagacc cagcctgtgt
421 ctttggctaa cacccagccc cgagggcccc cagcctcatc tccggctcca gcccctaagt
481 tttctccagt gactcctaag tttactcctg tggcttccaa gttcagtcct ggagccccag
541 gtggatctgg gtcacaacca aatcaaaaat tggggcaccc cgaagctctt tctgctggca
601 caggctcccc tcaacctccc agcttcacct atgcccagca gagggagaag ccccgagtgc
661 aggagaagca gcaccccgtg cccccaccgg ctcagaacca aaaccaggtg cgctcccctg
721 gggccccagg gcccctgact ctgaaggagg tggaggagct ggagcagctg acccagcagc
781 taatgcagga catggagcat cctcagaggc agaatgtggc tgtcaacgaa ctctgcggcc
841 gatgccatca acccctggcc cgggcgcagc cagccgtccg cgctctaggg cagctgttcc
901 acatcgcctg cttcacctgc caccagtgtg cgcagcagct ccagggccag cagttctaca
961 gtctggaggg ggcgccgtac tgcgagggct gttacactga caccctggag aagtgtaaca
1021 cctgcggcga gcccatcact gaccgcatgc tgagggccac gggcaaggcc tatcacccgc
1081 actgcttcac ctgtgtggtc tgcgcccgcc ccctggaggg cacctccttc atcgtggacc
1141 aggccaaccg gccccactgt gtccccgact accacaagca gtacgccccg aggtgctccg
1201 tctgctctga gcccatcatg cctgagcctg gccgagatga gactgtgcga gtggtcgccc
1261 tggacaagaa cttccacatg aagtgttaca agtgtgagga ctgcgggaag cccctgtcga
1321 ttgaggcaga tgacaatggc tgcttccccc tggacggtca cgtgctctgt cggaagtgcc
1381 acactgctag agcccagacc tgagtgagga caggccctct tcagaccgca gtccatgccc
1441 cattgtggac cacccacact gagaccacct gcccccacct cagttattgt tttgatgtct
1501 agcccctccc atttccaacc cctccctagc atcccaggtg ccctgaccca ggacccaaca
1561 tggtctaggg atgcaggatc cccgccctgg ggtctggtcc tcgcccatcc tgcagggatt
1621 gcccaccgtc ttccagacac cccacctgag gggggcacca ggtttagtgc tgctgctttc
1681 actgctgcac ccgcgccctc ggccggcccc ccgagcagcc tttgtactct gcttgcggag
1741 ggctgggaga ccctccagga cattcccacc ctcccccatg ctgccaagtt gtagctatag
1801 ctacaaataa aaaaaaacct tgttttccag aaaaaaaaaa aaaaaaaaa
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