LOCUS BC014846 2138 bp mRNA linear HUM 24-JUL-2006
DEFINITION Homo sapiens polo-like kinase 1 (Drosophila), mRNA (cDNA clone
MGC:9748 IMAGE:3854860), complete cds.
ACCESSION BC014846
VERSION BC014846.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2138)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2138)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 13 Row: c Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34147632.
FEATURES Location/Qualifiers
source 1..2138
/db_xref="H-InvDB:HIT000036868"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9748 IMAGE:3854860"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_65"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2138
/gene="PLK1"
/gene_synonym="STPK13"
/db_xref="GeneID:5347"
/db_xref="HGNC:HGNC:9077"
/db_xref="MIM:602098"
CDS 7..1818
/gene="PLK1"
/gene_synonym="STPK13"
/codon_start=1
/product="polo-like kinase 1 (Drosophila)"
/protein_id="AAH14846.1"
/db_xref="GeneID:5347"
/db_xref="HGNC:HGNC:9077"
/db_xref="MIM:602098"
/translation="MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVL
VDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEI
SIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQI
VLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYI
APEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINP
VAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDP
SNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSER
GLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDS
LQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARL
PYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSL
LEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS"
BASE COUNT 479 a 634 c 574 g 451 t
ORIGIN
1 gggagcatga gtgctgcagt gactgcaggg aagctggcac gggcaccggc cgaccctggg
61 aaagccgggg tccccggagt tgcagctccc ggagctccgg cggcggctcc accggcgaaa
121 gagatcccgg aggtcctagt ggacccacgc agccggcggc gctatgtgcg gggccgcttt
181 ttgggcaagg gcggctttgc caagtgcttc gagatctcgg acgcggacac caaggaggtg
241 ttcgcgggca agattgtgcc taagtctctg ctgctcaagc cgcaccagag ggagaagatg
301 tccatggaaa tatccattca ccgcagcctc gcccaccagc acgtcgtagg attccacggc
361 tttttcgagg acaacgactt cgtgttcgtg gtgttggagc tctgccgccg gaggtctctc
421 ctggagctgc acaagaggag gaaagccctg actgagcctg aggcccgata ctacctacgg
481 caaattgtgc ttggctgcca gtacctgcac cgaaaccgag ttattcatcg agacctcaag
541 ctgggcaacc ttttcctgaa tgaagatctg gaggtgaaaa taggggattt tggactggca
601 accaaagtcg aatatgacgg ggagaggaag aagaccctgt gtgggactcc taattacata
661 gctcccgagg tgctgagcaa gaaagggcac agtttcgagg tggatgtgtg gtccattggg
721 tgtatcatgt ataccttgtt agtgggcaaa ccaccttttg agacttcttg cctaaaagag
781 acctacctcc ggatcaagaa gaatgaatac agtattccca agcacatcaa ccccgtggcc
841 gcctccctca tccagaagat gcttcagaca gatcccactg cccgcccaac cattaacgag
901 ctgcttaatg acgagttctt tacttctggc tatatccctg cccgtctccc catcacctgc
961 ctgaccattc caccaaggtt ttcgattgct cccagcagcc tggaccccag caaccggaag
1021 cccctcacag tcctcaataa aggcttggag aaccccctgc ctgagcgtcc ccgggaaaaa
1081 gaagaaccag tggttcgaga gacaggtgag gtggtcgact gccacctcag tgacatgctg
1141 cagcagctgc acagtgtcaa tgcctccaag ccctcggagc gtgggctggt caggcaagag
1201 gaggctgagg atcctgcctg catccccatc ttctgggtca gcaagtgggt ggactattcg
1261 gacaagtacg gccttgggta tcagctctgt gataacagcg tgggggtgct cttcaatgac
1321 tcaacacgcc tcatcctcta caatgatggt gacagcctgc agtacataga gcgtgacggc
1381 actgagtcct acctcaccgt gagttcccat cccaactcct tgatgaagaa gatcaccctc
1441 cttaaatatt tccgcaatta catgagcgag cacttgctga aggcaggtgc caacatcacg
1501 ccgcgcgaag gtgatgagct cgcccggctg ccctacctac ggacctggtt ccgcacccgc
1561 agcgccatca tcctgcacct cagcaacggc agcgtgcaga tcaacttctt ccaggatcac
1621 accaagctca tcttgtgccc actgatggca gccgtgacct acatcgacga gaagcgggac
1681 ttccgcacat accgcctgag tctcctggag gagtacggct gctgcaagga gctggccagc
1741 cggctccgct acgcccgcac tatggtggac aagctgctga gctcacgctc ggccagcaac
1801 cgtctcaagg cctcctaata gctgccctcc cctccggact ggtgccctcc tcactcccac
1861 ctgcatctgg ggcccatact ggttggctcc cgcggtgcca tgtctgcagt gtgcccccca
1921 gccccggtgg ctgggcagag ctgcatcatc cttgcaggtg ggggttgctg tataagttat
1981 ttttgtacat gttcgggtgt gggttctaca gccttgtccc cctccccctc aaccccacca
2041 tatgaattgt acagaatatt tctattgaat tcggaactgt cctttccttg gctttatgca
2101 cattaaacag atgtgaatat tcaaaaaaaa aaaaaaaa
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