LOCUS BC013400 3840 bp mRNA linear HUM 09-JUN-2008
DEFINITION Homo sapiens discoidin domain receptor tyrosine kinase 1, mRNA
(cDNA clone MGC:3909 IMAGE:2964574), complete cds.
ACCESSION BC013400
VERSION BC013400.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3840)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3840)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC013400.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 10 Row: f Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 38327631.
FEATURES Location/Qualifiers
source 1..3840
/db_xref="H-InvDB:HIT000036249_05"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3909 IMAGE:2964574"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3840
/gene="DDR1"
/gene_synonym="CD167"
/gene_synonym="DDR"
/gene_synonym="MCK10"
/gene_synonym="PTK3"
/gene_synonym="RTK6"
/gene_synonym="TRKE"
/db_xref="GeneID:780"
/db_xref="HGNC:HGNC:2730"
/db_xref="MIM:600408"
CDS 334..2964
/gene="DDR1"
/gene_synonym="CD167"
/gene_synonym="DDR"
/gene_synonym="MCK10"
/gene_synonym="PTK3"
/gene_synonym="RTK6"
/gene_synonym="TRKE"
/codon_start=1
/product="discoidin domain receptor tyrosine kinase 1"
/protein_id="AAH13400.1"
/db_xref="GeneID:780"
/db_xref="HGNC:HGNC:2730"
/db_xref="MIM:600408"
/translation="MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPD
SDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGT
QGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMV
ARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGH
TVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDR
LRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAV
SVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPP
TNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKA
ERRVLEEELTVHLSVPGDTILINNRPGPREPPPYQEPRPRGNPPHSAPCVPNGSAYSG
DYMEPEKPGAPLLPPPPQNSVPHYAEADIVTLQGVTGGNTYAVPALPPGAVGDGPPRV
DFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDA
TKNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLE
DKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGEN
FTIKIADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWE
VLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESE
QRPPFSQLHRFLAEDALNTV"
BASE COUNT 713 a 1179 c 1160 g 788 t
ORIGIN
1 gtcttcccct cgtgggccct gagcgggact gcagccagcc ccctggggcg ccagctttgg
61 aggcccccga cagctgctct cgggagccgc ctcccgacac ccgagccccg ccggcgcctc
121 ccgctcccgg ctcccggctc ctggctccct ccgcctcccc cgcccctcgc cccgccgccg
181 aagaggcccc gctcccgggt cggacgcctg ggtctgccgg gaagagcgat gagaggtgtc
241 tgaaggtggc tattcactga gcgatggggt tggacttgaa ggaatgccaa gagatgctgc
301 ccccaccccc ttaggcccga gggatcagga gctatgggac cagaggccct gtcatcttta
361 ctgctgctgc tcttggtggc aagtggagat gctgacatga agggacattt tgatcctgcc
421 aagtgccgct atgccctggg catgcaggac cggaccatcc cagacagtga catctctgct
481 tccagctcct ggtcagattc cactgccgcc cgccacagca ggttggagag cagtgacggg
541 gatggggcct ggtgccccgc agggtcggtg tttcccaagg aggaggagta cttgcaggtg
601 gatctacaac gactgcacct ggtggctctg gtgggcaccc agggacggca tgccgggggc
661 ctgggcaagg agttctcccg gagctaccgg ctgcgttact cccgggatgg tcgccgctgg
721 atgggctgga aggaccgctg gggtcaggag gtgatctcag gcaatgagga ccctgaggga
781 gtggtgctga aggaccttgg gccccccatg gttgcccgac tggttcgctt ctacccccgg
841 gctgaccggg tcatgagcgt ctgtctgcgg gtagagctct atggctgcct ctggagggat
901 ggactcctgt cttacactgc ccctgtgggg cagacaatgt atttatctga ggccgtgtac
961 ctcaacgact ccacctatga cggacatacc gtgggcggac tgcagtatgg gggtctgggc
1021 cagctggcag atggtgtggt ggggctggat gactttagga agagtcagga gctgcgggtc
1081 tggccaggct atgactatgt gggatggagc aaccacagct tctccagtgg ctatgtggag
1141 atggagtttg agtttgaccg gctgagggcc ttccaggcta tgcaggtcca ctgtaacaac
1201 atgcacacgc tgggagcccg tctgcctggc ggggtggaat gtcgcttccg gcgtggccct
1261 gccatggcct gggaggggga gcccatgcgc cacaacctag ggggcaacct gggggacccc
1321 agagcccggg ctgtctcagt gccccttggc ggccgtgtgg ctcgctttct gcagtgccgc
1381 ttcctctttg cggggccctg gttactcttc agcgaaatct ccttcatctc tgatgtggtg
1441 aacaattcct ctccggcact gggaggcacc ttcccgccag ccccctggtg gccgcctggc
1501 ccacctccca ccaacttcag cagcttggag ctggagccca gaggccagca gcccgtggcc
1561 aaggccgagg ggagcccgac cgccatcctc atcggctgcc tggtggccat catcctgctc
1621 ctgctgctca tcattgccct catgctctgg cggctgcact ggcgcaggct cctcagcaag
1681 gctgaacgga gggtgttgga agaggagctg acggttcacc tctctgtccc tggggacact
1741 atcctcatca acaaccgccc aggtcctaga gagccacccc cgtaccagga gccccggcct
1801 cgtgggaatc cgccccactc cgctccctgt gtccccaatg gctctgccta cagtggggac
1861 tatatggagc ctgagaagcc aggcgccccg cttctgcccc cacctcccca gaacagcgtc
1921 ccccattatg ccgaggctga cattgttacc ctgcagggcg tcaccggggg caacacctat
1981 gctgtgcctg cactgccccc aggggcagtc ggggatgggc cccccagagt ggatttccct
2041 cgatctcgac tccgcttcaa ggagaagctt ggcgagggcc agtttgggga ggtgcacctg
2101 tgtgaggtcg acagccctca agatctggtt agtcttgatt tcccccttaa tgtgcgtaag
2161 ggacaccctt tgctggtagc tgtcaagatc ttacggccag atgccaccaa gaatgccagg
2221 aatgatttcc tgaaagaggt gaagatcatg tcgaggctca aggacccaaa catcattcgg
2281 ctgctgggcg tgtgtgtgca ggacgacccc ctctgcatga ttactgacta catggagaac
2341 ggcgacctca accagttcct cagtgcccac cagctggagg acaaggcagc cgagggggcc
2401 cctggggacg ggcaggctgc gcaggggccc accatcagct acccaatgct gctgcatgtg
2461 gcagcccaga tcgcctccgg catgcgctat ctggccacac tcaactttgt acatcgggac
2521 ctggccacgc ggaactgcct agttggggaa aatttcacca tcaaaatcgc agactttggc
2581 atgagccgga acctctatgc tggggactat taccgtgtgc agggccgggc agtgctgccc
2641 atccgctgga tggcctggga gtgcatcctc atggggaagt tcacgactgc gagtgacgtg
2701 tgggcctttg gtgtgaccct gtgggaggtg ctgatgctct gtagggccca gccctttggg
2761 cagctcaccg acgagcaggt catcgagaac gcgggggagt tcttccggga ccagggccgg
2821 caggtgtacc tgtcccggcc gcctgcctgc ccgcagggcc tatatgagct gatgcttcgg
2881 tgctggagcc gggagtctga gcagcgacca cccttttccc agctgcatcg gttcctggca
2941 gaggatgcac tcaacacggt gtgaatcaca catccagctg cccctccctc agggagcgat
3001 ccaggggaag ccagtgacac taaaacaaga ggacacaatg gcacctctgc ccttcccctc
3061 ccgacagccc atcacctcta atagaggcag tgagactgca ggtgggctgg gcccacccag
3121 ggagctgatg ccccttctcc ccttcctgga cacactctca tgtccccttc ctgttcttcc
3181 ttcctagaag cccctgtcgc ccacccagct ggtcctgtgg atgggatcct ctccaccctc
3241 ctctagccat cccttgggga agggtgggga gaaatatagg atagacactg gacatggccc
3301 attggagcac ctgggcccca ctggacaaca ctgattcctg gagaggtggc tgcgccccca
3361 gcttctctct ccctgtcaca cactggaccc cactggctga gaatctgggg gtgaggagga
3421 caagaaggag aggaaaatgt ttccttgtgc ctgctcctgt acttgtcctc agcttgggct
3481 tcttcctcct ccatcacctg aaacactgga cctgggggta gccccgcccc agccctcagt
3541 cacccccact tcccacttgc agtcttgtag ctagaacttc tctaagccta tacgtttctg
3601 tggagtaaat attgggattg gggggaaaga gggagcaacg gcccatagcc ttggggttgg
3661 acatctctag tgtagctgcc acattgattt ttctataatc acttggggtt tgtacatttt
3721 tggggggaga gacacagatt tttacactaa tatatggacc tagcttgagg caattttaat
3781 cccctgcact aggcaggtaa taataaaggt tgagttttcc acaaaaaaaa aaaaaaaaaa
//