LOCUS BC009470 1843 bp mRNA linear HUM 15-JUL-2006 DEFINITION Homo sapiens protein kinase, interferon-inducible double stranded RNA dependent activator, mRNA (cDNA clone MGC:1978 IMAGE:3503747), complete cds. ACCESSION BC009470 VERSION BC009470.1 KEYWORDS MGC. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 1843) AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A. CONSRTM Mammalian Gene Collection Program Team TITLE Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002) PUBMED 12477932 REFERENCE 2 (bases 1 to 1843) CONSRTM NIH MGC Project TITLE Direct Submission JOURNAL Submitted (19-JUN-2001) National Institutes of Health, Mammalian Gene Collection (MGC), Bethesda, MD 20892-2590, USA REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov COMMENT Contact: MGC help desk Email: cgapbs-r@mail.nih.gov Tissue Procurement: ATCC cDNA Library Preparation: Rubin Laboratory cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL) DNA Sequencing by: Genome Sequence Centre, BC Cancer Agency, Vancouver, BC, Canada info@bcgsc.bc.ca Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao, Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra. Clone distribution: MGC clone distribution information can be found through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov Series: IRAL Plate: 6 Row: d Column: 22 This clone was selected for full length sequencing because it passed the following selection criteria: matched mRNA gi: 32261293. FEATURES Location/Qualifiers source 1..1843 /db_xref="H-InvDB:HIT000034386" /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /clone="MGC:1978 IMAGE:3503747" /tissue_type="Brain, neuroblastoma" /clone_lib="NIH_MGC_19" /lab_host="DH10B-R" /note="Vector: pOTB7" gene 1..1843 /gene="PRKRA" /gene_synonym="HSD14" /gene_synonym="PACT" /gene_synonym="RAX" /db_xref="GeneID:8575" /db_xref="HGNC:HGNC:9438" /db_xref="MIM:603424" CDS 108..1049 /gene="PRKRA" /gene_synonym="HSD14" /gene_synonym="PACT" /gene_synonym="RAX" /codon_start=1 /product="protein kinase, interferon-inducible double stranded RNA dependent activator" /protein_id="AAH09470.1" /db_xref="GeneID:8575" /db_xref="HGNC:HGNC:9438" /db_xref="MIM:603424" /translation="MSQSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGM KTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKAN ASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYT TICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSL RNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAEL STSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK" BASE COUNT 635 a 366 c 360 g 482 t ORIGIN 1 ggaggaggtg gcggcgctgg agctcctccc ggggaccagc gacccgggga gcgagcacgt 61 cgctccgcac cgctcttcct ccagccgctg agccgtccct tctcgccatg tcccagagca 121 ggcaccgcgc cgaggccccg ccgctggagc gcgaggacag tgggaccttc agtttgggga 181 agatgataac agctaagcca gggaaaacac cgattcaggt attacacgaa tacggcatga 241 agaccaagaa catcccagtt tatgaatgtg aaagatctga tgtgcaaata cacgtgccca 301 ctttcacctt cagagtaacc gttggtgaca taacctgcac aggtgaaggt acaagtaaga 361 agctggcgaa acatagagct gcagaggctg ccataaacat tttgaaagcc aatgcaagta 421 tttgctttgc agttcctgac cccttaatgc ctgacccttc caagcaacca aagaaccagc 481 ttaatcctat tggttcatta caggaattgg ctattcatca tggctggaga cttcctgaat 541 ataccctttc ccaggaggga ggacctgctc ataagagaga atatactaca atttgcaggc 601 tagagtcatt tatggaaact ggaaaggggg catcaaaaaa gcaagccaaa aggaatgctg 661 ctgagaaatt tcttgccaaa tttagtaata tttctccaga gaaccacatt tctttaacaa 721 atgtagtagg acattcttta ggatgtactt ggcattcctt gaggaattct cctggtgaaa 781 agatcaactt actgaaaaga agcctcctta gtattccaaa tacagattac atccagctgc 841 ttagtgaaat tgccaaggaa caaggtttta atataacata tttggatata gatgaactga 901 gcgccaatgg acaatatcaa tgtcttgctg aactgtccac cagccccatc acagtctgtc 961 atggctccgg tatctcctgt ggcaatgcac aaagtgatgc agctcacaat gctttgcagt 1021 atttaaagat aatagcagaa agaaagtaaa tctggagcaa cttaaaaaat ctttcagtag 1081 cacataaaaa gttcccctct ggccccttcc caagtaaaac ttttaccgta gtgtttatgt 1141 cttgtttcta aatctcttca tagattccat caacactcca gatttaatta tctcctcata 1201 gttgttatta agctcttttt aatggcttca actttgtatc agtatactgt atttataaac 1261 tttgtaccac aagagagagt gtagcaccca ttttacagtg ccatgcacat cagagaaaga 1321 aactgcatgt ttgttgttga tgatgaaata aaaatgctag cgacagtctt tcttactggt 1381 gcttaagctc ttctttgcac aaagctttat aaagggaatt caaaggaagc cctttagaat 1441 tagagtcttg agggacagca ctaacaggcc tttattaagt atgattgatt gttaaatttc 1501 agggaacatg attggtctgc tgtgtatttg aattcatgta acaaagaact gttacgatgg 1561 gattctgctc attttattaa aaagctactg acttgactgt catcctgttc ttgttagcca 1621 ttgtgaataa gattttaatg ttgataattc tgttatttac atatctctaa tttactttga 1681 aattcaaagg tgaaaataaa aaatgatggc ctaagtaaaa tttaaaaaaa aaaaaaaaaa 1741 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1801 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaccccc ggg //