LOCUS BC002323 2192 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens zyxin, mRNA (cDNA clone IMAGE:3504464), partial cds.
ACCESSION BC002323
VERSION BC002323.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2192)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2192)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-FEB-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC002323.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 7 Row: c Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21359838.
FEATURES Location/Qualifiers
source 1..2192
/db_xref="H-InvDB:HIT000086120"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3504464"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2192
/gene="ZYX"
/db_xref="GeneID:7791"
/db_xref="MIM:602002"
CDS <1..1746
/gene="ZYX"
/codon_start=1
/product="ZYX protein"
/protein_id="AAH02323.2"
/db_xref="GeneID:7791"
/db_xref="MIM:602002"
/translation="PSPPGWRLLRTGTQSLRTRRRGGHPRRGAHAPACARPGHGGPPP
VSRDLRFGLGSGFLRPAEEVRPCGGPKAQSESLPEDFPLPPPPLAGDGDDAEGALGGA
FPPPPPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEISL
SSLLDDMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPL
PQVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFS
PVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRV
QEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNEL
CGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTL
EKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQ
YAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLD
GHVLCRKCHTARAQT"
misc_feature 1177..1338
/gene="ZYX"
/note="LIM; Region: LIM domain. This family represents two
copies of the LIM structural domain"
/db_xref="CDD:pfam00412"
misc_feature 1354..1512
/gene="ZYX"
/note="LIM; Region: Zinc-binding domain present in Lin-11,
Isl-1, Mec-3. Zinc-binding domain family. Some LIM domains
bind protein partners via tyrosine-containing motifs. LIM
domains are found in many key regulators of developmental
pathways"
/db_xref="CDD:smart00132"
misc_feature 1534..1722
/gene="ZYX"
/note="LIM; Region: Zinc-binding domain present in Lin-11,
Isl-1, Mec-3. Zinc-binding domain family. Some LIM domains
bind protein partners via tyrosine-containing motifs. LIM
domains are found in many key regulators of developmental
pathways"
/db_xref="CDD:smart00132"
BASE COUNT 418 a 797 c 579 g 398 t
ORIGIN
1 ccctccccgc ccggctggag gctgctccgg accgggacgc agagtctgcg gacccggcgc
61 cgaggcggcc acccgagacg cggcgcgcac gctccggcct gcgcccggcc cggccatggc
121 ggccccccgc ccgtctcccg cgatctccgt ttcggtctcg gctccggctt tttacgcccc
181 gcagaagaag ttcggccctg tggtggcccc aaagcccaaa gtgaatccct tccggaagac
241 tttcccctgc ctccacctcc ccttgctggg gatggcgacg atgcagaggg tgctctggga
301 ggtgccttcc cgccgccccc tcccccgatc gaggaatcat ttccccctgc gcctctggag
361 gaggagatct tcccttcccc gccgcctcct ccggaggagg agggagggcc tgaggccccc
421 ataccgcccc caccacagcc cagggagaag gtgagcagta ttgatttgga gatctctctg
481 tcctcactgc tggatgacat gaccaagaat gatcctttca aagcccgggt gtcatctgga
541 tatgtgcccc caccagtggc cactccattc agttccaagt ccagtaccaa gcctgcagcc
601 gggggcacag cacccctgcc tccttggaag tccccttcca gctcccagcc tctgccccag
661 gttccggctc cggctcagag ccagacacag ttccatgttc agccccagcc ccagcccaag
721 cctcaggtcc aactccatgt ccagtcccag acccagcctg tgtctttggc taacacccag
781 ccccgagggc ccccagcctc atctccggct ccagccccta agttttctcc agtgactcct
841 aagtttactc ctgtggcttc caagttcagt cctggagccc caggtggatc tgggtcacaa
901 ccaaatcaaa aattggggca ccccgaagct ctttctgctg gcacaggctc ccctcaacct
961 cccagcttca cctatgccca gcagagggag aagccccgag tgcaggagaa gcagcacccc
1021 gtgcccccac cggctcagaa ccaaaaccag gtgcgctccc ctggggcccc agggcccctg
1081 actctgaagg aggtggagga gctggagcag ctgacccagc agctaatgca ggacatggag
1141 catcctcaga ggcagaatgt ggctgtcaac gaactctgcg gccgatgcca tcaacccctg
1201 gcccgggcgc agccagccgt ccgcgctcta gggcagctgt tccacatcgc ctgcttcacc
1261 tgccaccagt gtgcgcagca gctccagggc cagcagttct acagtctgga gggggcgccg
1321 tactgcgagg gctgttacac tgacaccctg gagaagtgta acacctgcgg ggagcccatc
1381 actgaccgca tgctgagggc cacgggcaag gcctatcacc cgcactgctt cacctgtgtg
1441 gtctgcgccc gccccctgga gggcacctcc ttcatcgtgg accaggccaa ccggccccac
1501 tgtgtccccg actaccacaa gcagtacgcc ccgaggtgct ccgtctgctc tgagcccatc
1561 atgcctgagc ctggccgaga tgagactgtg cgagtggtcg ccctggacaa gaacttccac
1621 atgaagtgtt acaagtgtga ggactgcggg aagcccctgt cgattgaggc agatgacaat
1681 ggctgcttcc ccctggacgg tcacgtgctc tgtcggaagt gccacactgc tagagcccag
1741 acctgagtga ggacaggccc tcttcagacc gcagtccatg ccccattgtg gaccacccac
1801 actgagacca cctgccccca cctcagttat tgttttgatg tctagcccct cccatttcca
1861 acccctccct agcatcccag gtgccctgac ccaggaccca acatggtcta gggatgcagg
1921 atccccgccc tggggtctgg tcctcgccca tcctgcaggg attgcccacc gtcttccaga
1981 caccccacct gaggggggca ccaggtttag tgctgctgct ttcactgctg cacccgcgcc
2041 ctcggctggc cccccgagca gcctttgtac tctgcttgcg gagggctggg agaccctcca
2101 ggacattccc accctccccc atgctgccaa gttgtagcta tagctacaaa taaaaaaaaa
2161 ccttgttttc cagaaaaaaa aaaaaaaaaa aa
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