LOCUS BC001596 2640 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens BRCA1 associated protein-1 (ubiquitin carboxy-terminal
hydrolase), mRNA (cDNA clone MGC:1530 IMAGE:3543914), complete cds.
ACCESSION BC001596
VERSION BC001596.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2640)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2640)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: m Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 19718752.
FEATURES Location/Qualifiers
source 1..2640
/db_xref="H-InvDB:HIT000030505"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1530 IMAGE:3543914"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2640
/gene="BAP1"
/gene_synonym="HUCEP-13"
/gene_synonym="hucep-6"
/gene_synonym="KIAA0272"
/db_xref="GeneID:8314"
/db_xref="HGNC:HGNC:950"
/db_xref="MIM:603089"
CDS 116..2305
/gene="BAP1"
/gene_synonym="HUCEP-13"
/gene_synonym="hucep-6"
/gene_synonym="KIAA0272"
/codon_start=1
/product="BRCA1 associated protein-1 (ubiquitin
carboxy-terminal hydrolase)"
/protein_id="AAH01596.1"
/db_xref="GeneID:8314"
/db_xref="HGNC:HGNC:950"
/db_xref="MIM:603089"
/translation="MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVY
GFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLN
CSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLS
AVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLAT
AGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKS
QESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKL
VVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQ
QYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAE
KLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLR
SPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAE
DGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSG
EKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISML
AQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ"
BASE COUNT 604 a 760 c 799 g 477 t
ORIGIN
1 gcccgttgtc tgtgtgtggg actgaggggc cccgggggcg gtgggggctc ccggtggggg
61 cagcggtggg gagggagggc ctggacatgg cgctgagggg ccgccccgcg ggaagatgaa
121 taagggctgg ctggagctgg agagcgaccc aggcctcttc accctgctcg tggaagattt
181 cggtgtcaag ggggtgcaag tggaggagat ctacgacctt cagagcaaat gtcagggccc
241 tgtatatgga tttatcttcc tgttcaaatg gatcgaagag cgccggtccc ggcgaaaggt
301 ctctaccttg gtggatgata cgtccgtgat tgatgatgat attgtgaata acatgttctt
361 tgcccaccag ctgataccca actcttgtgc aactcatgcc ttgctgagcg tgctcctgaa
421 ctgcagcagc gtggacctgg gacccaccct gagtcgcatg aaggacttca ccaagggttt
481 tagccctgag agcaaaggat atgcgattgg caatgccccg gagttggcca aggcccataa
541 tagccatgcc aggcccgagc cacgccacct ccctgagaag cagaatggcc ttagtgcagt
601 gcggaccatg gaggcgttcc actttgtcag ctatgtgcct atcacaggcc ggctctttga
661 gctggatggg ctgaaggtct accccattga ccatgggccc tggggggagg acgaggagtg
721 gacagacaag gcccggcggg tcatcatgga gcgtatcggc ctcgccactg caggggagcc
781 ctaccacgac atccgcttca acctgatggc agtggtgccc gaccgcagga tcaagtatga
841 ggccaggctg catgtgctga aggtgaaccg tcagacagta ctagaggctc tgcagcagct
901 gataagagta acacagccag agctgattca gacccacaag tctcaagagt cacagctgcc
961 tgaggagtcc aagtcagcca gcaacaagtc cccgctggtg ctggaagcaa acagggcccc
1021 tgcagcctct gagggcaacc acacagatgg tgcagaggag gcggctggtt catgcgcaca
1081 agccccatcc cacagccctc ccaacaaacc caagctagtg gtgaagcctc caggcagcag
1141 cctcaatggg gttcacccca accccactcc cattgtccag cggctgccgg cctttctaga
1201 caatcacaat tatgccaagt cccccatgca ggaggaagaa gacctggcgg caggtgtggg
1261 ccgcagccga gttccagtcc gcccacccca gcagtactca gatgatgagg atgactatga
1321 ggatgacgag gaggatgacg tgcagaacac caactctgcc cttaggtata aggggaaggg
1381 aacagggaag ccaggggcat tgagcggttc tgctgatggg caactgtcag tgctgcagcc
1441 caacaccatc aacgtcttgg ctgagaagct caaagagtcc cagaaggacc tctcaattcc
1501 tctgtccatc aagactagca gcggggctgg gagtccggct gtggcagtgc ccacacactc
1561 gcagccctca cccaccccca gcaatgagag tacagacacg gcctctgaga tcggcagtgc
1621 tttcaactcg ccactgcgct cgcctatccg ctcagccaac ccgacgcggc cctccagccc
1681 tgtcacctcc cacatctcca aggtgctttt tggagaggat gacagcctgc tgcgtgttga
1741 ctgcatacgc tacaaccgtg ctgtccgtga tctgggtcct gtcatcagca caggcctgct
1801 gcacctggct gaggatgggg tgctgagtcc cctggcgctg acagagggtg ggaagggttc
1861 ctcgccctcc atcagaccaa tccaaggcag ccaggggtcc agcagcccag tggagaagga
1921 ggtcgtggaa gccacggaca gcagagagaa gacggggatg gtgaggcctg gcgagccctt
1981 gagtggggag aaatactcac ccaaggagct gctggcactg ctgaagtgtg tggaggctga
2041 gattgcaaac tatgaggcgt gcctcaagga ggaggtagag aagaggaaga agttcaagat
2101 tgatgaccag agaaggaccc acaactacga tgagttcatc tgcaccttta tctccatgct
2161 ggctcaggaa ggcatgctgg ccaacctagt ggagcagaac atctccgtgc ggcggcgcca
2221 aggggtcagc atcggccggc tccacaagca gcggaagcct gaccggcgga aacgctctcg
2281 cccctacaag gccaagcgcc agtgaggact gctggccctg actctgcagc ccactcttgc
2341 cgtgtggccc tcaccagggt ccttccctgc cccacttccc cttttcccag tattactgaa
2401 tagtcccagc tggagagtcc aggccctggg aatgggagga accaggccac attccttcca
2461 tcgtgccctg aggcctgaca cggcagatca gccccatagt gctcaggagg cagcatctgg
2521 agttggggca cagcgaggta ctgcagcttc ctccacagcc ggctgtggag cagcaggacc
2581 tggcccttct gcctgggcag cagaatatat attttaccta tcaaaaaaaa aaaaaaaaaa
//