LOCUS       AY293285                 921 bp    mRNA    linear   ROD 18-JUN-2003
DEFINITION  Mus musculus B and T lymphocyte attenuator (Btla) mRNA, complete
            cds.
ACCESSION   AY293285
VERSION     AY293285.1
KEYWORDS    .
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 921)
  AUTHORS   Watanabe,N., Gavrieli,M., Sedy,J.R., Yang,J., Fallarino,F.,
            Loftin,S.K., Hurchla,M.A., Zimmerman,N., Sim,J., Zang,X.,
            Murphy,T.L., Russell,J.H., Allison,J.P. and Murphy,K.M.
  TITLE     BTLA is a lymphocyte inhibitory receptor with similarities to
            CTLA-4 and PD-1
  JOURNAL   Nat. Immunol. 4 (7), 670-679 (2003)
   PUBMED   12796776
REFERENCE   2  (bases 1 to 921)
  AUTHORS   Murphy,K.M., Watanabe,N., Yang,J. and Murphy,T.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-MAY-2003) Pathology, Washington University, 660 S.
            Euclid, St. Louis, MO 63110, USA
FEATURES             Location/Qualifiers
     source          1..921
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="129/SvEv"
                     /db_xref="taxon:10090"
     gene            1..921
                     /gene="Btla"
     CDS             1..921
                     /gene="Btla"
                     /note="immunoregulatory inhibitory receptor; similar to
                     CTLA-4 and PD-1"
                     /codon_start=1
                     /product="B and T lymphocyte attenuator"
                     /protein_id="AAP44002.1"
                     /translation="MKTVPAMLGTPRLFREFFILHLGLWSILCEKATKRNDEECEVQL
                     NIKRNSKHSAWTGELFKIECPVKYCVHRPNVTWCKHNGTIWVPLEVGPQLYTSWEENR
                     SVPVFVLHFKPIHLSDNGSYSCSTNFNSQVINSHSVTIHVRERTQNSSEHPLITVSDI
                     PDATNASGPSTMEERPGRTWLLYTLLPLGALLLLLACVCLLCFLKRIQGKEKKPSDLA
                     GRDTNLVDIPASSRTNHQALPSGTGIYDNDPWSSMQDESELTISLQSERNNQGIVYAS
                     LNHCVIGRNPRQENNMQEAPTEYASICVRS"
BASE COUNT          273 a          200 c          203 g          245 t
ORIGIN      
        1 atgaagacag tgcctgccat gcttgggact cctcggttat ttagggaatt cttcatcctc
       61 catctgggcc tctggagcat cctttgtgag aaagctacta agaggaatga tgaagagtgt
      121 gaagtgcaac ttaatattaa gaggaattcc aaacactctg cctggacagg agagttattt
      181 aaaattgaat gtcctgtgaa atactgtgtt catagaccta atgtgacttg gtgtaagcac
      241 aatggaacaa tctgggtacc ccttgaagtt ggtcctcagc tatacactag ttgggaagaa
      301 aatcgatcag ttccggtttt tgttctccat tttaaaccaa tacatctcag tgataacggg
      361 tcgtatagct gttctacaaa cttcaattct caagttatta atagccattc agtaaccatc
      421 catgtgagag aaaggactca aaactcttca gaacacccac taataacagt atctgacatc
      481 ccagatgcca ccaatgcctc aggaccatcc accatggaag agaggccagg caggacttgg
      541 ctgctttaca ccttgcttcc tttgggggca ttgcttctgc tccttgcctg tgtctgcctg
      601 ctctgctttc tgaaaaggat ccaagggaaa gaaaagaagc cttctgactt ggcaggaagg
      661 gacactaacc tggttgatat tccagccagt tccaggacaa atcaccaagc actgccatca
      721 ggaactggaa tttatgataa tgatccctgg tctagcatgc aggatgaatc tgaattgaca
      781 attagcttgc aatcagagag aaacaaccag ggcattgttt atgcttcttt gaaccattgt
      841 gttattggaa ggaatccaag acaggaaaac aacatgcagg aggcacccac agaatatgca
      901 tccatttgtg tgagaagtta a
//