LOCUS AY112984 3410 bp mRNA linear HUM 19-NOV-2003
DEFINITION Homo sapiens ubiquitin ligase NEDD4g (NEDD4L) mRNA, complete cds;
alternatively spliced.
ACCESSION AY112984
VERSION AY112984.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3410)
AUTHORS Qi,H., Grenier,J., Fournier,A. and Labrie,C.
TITLE Androgens differentially regulate the expression of NEDD4L
transcripts in LNCaP human prostate cancer cells
JOURNAL Mol. Cell. Endocrinol. 210 (1-2), 51-62 (2003)
PUBMED 14615060
REFERENCE 2 (bases 1 to 3410)
AUTHORS Qi,H. and Labrie,C.
TITLE Direct Submission
JOURNAL Submitted (16-MAY-2002) Oncology and Molecular Endocrinology
Research Center, Laval University, 2705, Boul. Laurier, Quebec G1V
4G2, Canada
COMMENT On Jul 15, 2003 this sequence version replaced AY112984.1.
FEATURES Location/Qualifiers
source 1..3410
/db_xref="H-InvDB:HIT000250709"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18q21.31"
gene 1..3410
/gene="NEDD4L"
/note="NEDD4-2"
CDS 204..3107
/gene="NEDD4L"
/note="alternatively spliced"
/codon_start=1
/product="ubiquitin ligase NEDD4g"
/protein_id="AAM76729.1"
/translation="MRRLAFEQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVP
DENRELALVQTKTIKKTLNPKWNEEFYFRVNPSNHRLLFEVFDENRLTRDDFLGQVDV
PLSHLPTEDPTMERPYTFKDFLLRPRSHKSRVKGFLRLKMAYMPKNGGQDEENSDQRD
DMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSL
MDVSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAG
DSLGLALPPPPASPGSRTSPQELSEELSRRLQITPDSNGEQFSSLIQREPSSRLRSCS
VTDAVAEQGHLPPPSAPAGRARSSTVTGGEEPTPSVAYVHTTPGLPSGWEERKDAKGR
TYYVNHNNRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPL
EGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFI
DHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKIT
QWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESY
RRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDN
YTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLND
MESVDSEYYNSLKWILENDPTELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKRE
YIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGDVDVNDWR
QHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGP
QLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD"
BASE COUNT 959 a 842 c 787 g 822 t
ORIGIN
1 gccatttcca gagaggaaca accgtgtaga ctgctttcct gggagtcaag ttaaaacttc
61 tctcctgtga ccttgtcacc cggcagtgga aagttaccct tggctgcagc cacgacttcc
121 gcatactctt cagaacttgc tctgcccttg agttttccag ctttccttta atgcactaaa
181 cctttaatat tgtattctcc taaatgagac gtctcgcatt tgagcaggga gagtcccgta
241 ttctcagagt aaaagttgtt tctggaattg atctcgccaa aaaggacatc tttggagcca
301 gtgatccgta tgtgaaactt tcattgtacg taccggatga gaatagagaa cttgctttgg
361 tccagacaaa aacaattaaa aagacactga acccaaaatg gaatgaagaa ttttatttca
421 gggtaaaccc atctaatcac agactcctat ttgaagtatt tgacgaaaat agactgacac
481 gagacgactt cctgggccag gtggacgtgc cccttagtca ccttccgaca gaagatccaa
541 ccatggagcg accctataca tttaaggact ttctcctcag accaagaagt cataagtctc
601 gagttaaggg atttttgcga ttgaaaatgg cctatatgcc aaaaaatgga ggtcaagatg
661 aagaaaacag tgaccagagg gatgacatgg agcatggatg ggaagttgtt gactcaaatg
721 actcggcttc tcagcaccaa gaggaacttc ctcctcctcc tctgcctccc gggtgggaag
781 aaaaagtgga caatttaggc cgaacttact atgtcaacca caacaaccgg accactcagt
841 ggcacagacc aagcctgatg gacgtgtcct cggagtcgga caataacatc agacagatca
901 accaggaggc agcacaccgg cgcttccgct cccgcaggca catcagcgaa gacttggagc
961 ccgagccctc ggagggcggg gatgtccccg agccttggga gaccatttca gaggaagtga
1021 atatcgctgg agactctctc ggtctggctc tgcccccacc accggcctcc ccaggatctc
1081 ggaccagccc tcaggagctg tcagaggaac taagcagaag gcttcagatc actccagact
1141 ccaatgggga acagttcagc tctttgattc aaagagaacc ctcctcaagg ttgaggtcat
1201 gcagtgtcac cgacgcagtt gcagaacagg gccatctacc accgcccagt gccccagctg
1261 ggagagcgcg ttcatcaact gtcacgggtg gtgaggaacc aacgccatca gtggcctatg
1321 tacataccac gccgggtctg ccttcaggct gggaagaaag aaaagatgct aaggggcgca
1381 catactatgt caatcataac aatcgaacca caacttggac tcgacctatc atgcagcttg
1441 cagaagatgg tgcgtccgga tcagccacaa acagtaacaa ccatctaatc gagcctcaga
1501 tccgccggcc tcgtagcctc agctcgccaa cagtaacttt atctgccccg ctggagggtg
1561 ccaaggactc acccgtacgt cgggctgtga aagacaccct ttccaaccca cagtccccac
1621 agccatcacc ttacaactcc cccaaaccac aacacaaagt cacacagagc ttcttgccac
1681 ccggctggga aatgaggata gcgccaaacg gccggccctt cttcattgat cataacacaa
1741 agactacaac ctgggaagat ccacgtttga aatttccagt acatatgcgg tcaaagacat
1801 ctttaaaccc caatgacctt ggcccccttc ctcctggctg ggaagaaaga attcacttgg
1861 atggccgaac gttttatatt gatcataata gcaaaattac tcagtgggaa gacccaagac
1921 tgcagaaccc agctattact ggtccggctg tcccttactc cagagaattt aagcagaaat
1981 atgactactt caggaagaaa ttaaagaaac ctgctgatat ccccaatagg tttgaaatga
2041 aacttcacag aaataacata tttgaagagt cctatcggag aattatgtcc gtgaaaagac
2101 cagatgtcct aaaagctaga ctgtggattg agtttgaatc agagaaaggt cttgactatg
2161 ggggtgtggc cagagaatgg ttcttcttac tgtccaaaga gatgttcaac ccctactacg
2221 gcctctttga gtactctgcc acggacaact acacccttca gatcaaccct aattcaggcc
2281 tctgtaatga ggatcatttg tcctacttca cttttattgg aagagttgct ggtctggccg
2341 tatttcatgg gaagctctta gatggtttct tcattagacc attttacaag atgatgttgg
2401 gaaagcagat aaccctgaat gacatggaat ctgtggatag tgaatattac aactctttga
2461 aatggatcct ggagaatgac cctactgagc tggacctcat gttctgcata gacgaagaaa
2521 actttggaca gacatatcaa gtggatttga agcccaatgg gtcagaaata atggtcacaa
2581 atgaaaacaa aagggaatat atcgacttag tcatccagtg gagatttgtg aacagggtcc
2641 agaagcagat gaacgccttc ttggagggat tcacagaact acttcctatt gatttgatta
2701 aaatttttga tgaaaatgag ctggagttgc tcatgtgcgg cctcggtgat gtggatgtga
2761 atgactggag acagcattct atttacaaga acggctactg cccaaaccac cccgtcattc
2821 agtggttctg gaaggctgtg ctactcatgg acgccgaaaa gcgtatccgg ttactgcagt
2881 ttgtcacagg gacatcgcga gtacctatga atggatttgc cgaactttat ggttccaatg
2941 gtcctcagct gtttacaata gagcaatggg gcagtcctga gaaactgccc agagctcaca
3001 catgctttaa tcgccttgac ttacctccat atgaaacctt tgaagattta cgagagaaac
3061 ttctcatggc cgtggaaaat gctcaaggat ttgaaggggt ggattaagca ccctgtgcct
3121 cgggggtggt tgttcttcaa gcaagttctg cttgcacttt tgcatttgcc taacagactt
3181 ttgcagaggc gatggcagag agcagctgca ggcatggtcc ctggagccga gccttcacca
3241 cgcactcgtc caagttcgga tgcgggaacc tggtcccagc ttgagttcct gcctttccca
3301 ccacaaatta tcaactggtt gatgtgtaca ctaattacat ttcaggagga cttaatgcta
3361 tttatgttgt gcctctgcag caaagccctt aataaatatt ttacatcctt
//