LOCUS AY081842 1646 bp mRNA linear HUM 23-AUG-2002
DEFINITION Homo sapiens transmembrane inner ear protein (TMIE) mRNA, complete
cds.
ACCESSION AY081842
VERSION AY081842.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1646)
AUTHORS Naz,S., Giguere,C.M., Kohrman,D.C., Mitchem,K.L., Riazuddin,S.,
Morell,R.J., Ramesh,A., Srisailpathy,S., Deshmukh,D., Riazuddin,S.,
Griffith,A.J., Friedman,T.B., Smith,R.J. and Wilcox,E.R.
TITLE Mutations in a novel gene, TMIE, are associated with hearing loss
linked to the DFNB6 locus
JOURNAL Am. J. Hum. Genet. 71 (3), 632-636 (2002)
PUBMED 12145746
REFERENCE 2 (bases 1 to 1646)
AUTHORS Naz,S., Giguere,C.M., Kohrman,D.C., Mitchem,K., Riazuddin,S.,
Morell,R., Ramesh,A., Srisailpaatahy,S., Deshmukh,D., Riazuddin,S.,
Griffith,A.J., Friedman,T.B., Smith,R.J.H. and Wilcox,E.R.
TITLE Direct Submission
JOURNAL Submitted (04-MAR-2002) NIDCD, NIH, 5-Research Court, Research
Boulevard, Rockville, MD 20850, USA
FEATURES Location/Qualifiers
source 1..1646
/db_xref="H-InvDB:HIT000084245"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p21"
gene 1..1646
/gene="TMIE"
CDS 156..623
/gene="TMIE"
/codon_start=1
/product="transmembrane inner ear protein"
/protein_id="AAL89820.1"
/translation="MAGWPGAGPLCVLGGAALGVCLAGVAGQLVEPSTAPPKPKPPPL
TKETVVFWDMRLWHVVGIFSLFVLSIIITLCCVFNCRVPRTRKEIEARYLQRKAAKMY
TDKLETVPPLNELTEVPGEDKKKKKKKKDSVDTVAIKVEEDEKNEAKKKKGEK"
BASE COUNT 358 a 457 c 545 g 286 t
ORIGIN
1 ggcggcgcgg gaacctgaca ccgaggatga ataaatgatg ctcgctgact acccgtggcc
61 aaagcccgtg gccaccgagc gccggctggc aggggcagtg accggcggcc ggcccgttcg
121 tccctgggct ccgcaagcgg cgcggtggca cgaagatggc ggggtggccg ggcgcgggtc
181 ccctctgcgt gctgggcggc gccgcactcg gggtgtgcct cgcgggggtt gccgggcagc
241 tggtggagcc cagcacggcc ccacccaagc ccaagccgcc tccgctgacc aaggagacag
301 tggtgttctg ggacatgcgc ctgtggcacg tggtgggcat cttttcgctc ttcgtgttgt
361 ccatcatcat cacgctgtgc tgtgtcttca actgtcgtgt gccacggacc cggaaggaga
421 tcgaagcccg gtacctgcag cgaaaggcag ccaagatgta cacagacaag ctggagactg
481 tgccacccct caatgagctc acagaagtcc caggagagga taagaagaag aagaagaaga
541 agaaggacag tgtggacaca gtggccatca aagtagagga ggatgagaag aatgaggcca
601 agaagaagaa aggagagaaa tgaagacatc ctgggcagct tgggctggcg ggccctggag
661 ctcaagccgt ggccggggtc caggcatgtt ggactctgag ctcatttggg gaccacagag
721 gctgtggtca gagagggaag ctgaggccca tggccacatc ctcatggccc atcaggggca
781 ggaaccagac aatctcgtag gtgtcctgcc ccccagccta ggcttggctc ctttcacccc
841 atccacatgg gtactgtctc ggcagaggtg gtctggtgcc accgtccctc tgcagataca
901 ctgctctccc cacccagacc tgcctgtctc ccaccctttc tgccagggat ggcagtggct
961 gtgaaggagt aatgggatat ggggttactt cagccaccct ttctggcacg aaatggctga
1021 agtgcatggg tcagggtgtg aggccacacc cagagtagcc atgaggaggc agagagggtc
1081 actgggggac actgtggcag caggagggac tctgtctggc cagggaggag ccccagtggt
1141 gagaagactt ccccaagcct ggcaggggat ccagctcaag ggagtaagta gaggtggctt
1201 cagaaatgga acccccagcc cagcagacat caagctcaag gcaatgggct accctcattt
1261 cacacgttgt gatgaagctg aggctgctgc caggcccggc atgaggcccc gaggctcgag
1321 ctcggggctg ggggctgcag ggctgggtca ggggtacaca gagctaaggc caatgggcta
1381 gagggtgccg gaaagagagc tggagtctgg gctcctcttg ggaatcagag tatatttaag
1441 aagccaaggg ggacctcggg ctgttctggt ggccccttct atgcccagct gtgctgggag
1501 gtcccagggc cctagaagat cacagcaggg ccttctgcct gctgaccata acagtgccag
1561 cttctttgca gcttcctctt ctaccatttc ccactacggg cacctaaaag aagcatctct
1621 gaccagaaga caaaggccca aatagc
//